Impaired kidney function

Also known as: Kidney impairment / Renal Impairment / Renal Impairments / Renal Insufficiency / Impaired Renal Function / Insufficiency renal / Renal impairment NOS

DrugDrug NameDrug Description
DB08898GlucarpidaseA carboxypeptidase enzyme used to treat toxic plasma methotrexate concentrations by providing an alternate elimination pathway for methotrexate in patients who have impaired renal function.
DrugDrug NameTargetType
DB08898GlucarpidaseMethotrexatetarget
DrugDrug NamePhaseStatusCount
DB12597ABL-0011Recruiting1
DB11804AZD-56721Completed1
DB05812Abiraterone1Completed1
DB14973Abrocitinib1Completed1
DB14906Adafosbuvir1Completed1
DB08916Afatinib1Completed1
DB06594Agomelatine1Completed1
DB09043Albiglutide1Completed1
DB01076Atorvastatin1Completed1
DB14857Avadomide1Completed1
DB00928Azacitidine1Recruiting1
DB06681Belatacept1Active Not Recruiting1
DB09258Bemiparin1Completed1
DB12364Betrixaban1Completed1
DB12464Bevenopran1Terminated1
DB11666Buparlisib1Completed1
DB05153Cabozantinib1Completed1
DB08875Cabozantinib1Completed1
DB08907Canagliflozin1Completed1
DB09061Cannabidiol1Withdrawn1
DB06634Casopitant1Completed2
DB01413Cefepime1Completed2
DB11777Cenderitide1Withdrawn1
DB01432Cholestyramine1Completed1
DB11890Cilengitide1Completed1
DB00515Cisplatin1Completed1
DB15194Cotadutide1Completed1
DB08865Crizotinib1Completed1
DB00531Cyclophosphamide1Completed1
DB01914D-glucose1Withdrawn1
DB14726Dabigatran1Completed1
DB06695Dabigatran etexilate1Completed1
DB08912Dabrafenib1Recruiting1
DB06637Dalfampridine1Completed1
DB13120Deferitazole1Completed1
DB11921Deflazacort1Completed1
DB14850Deleobuvir1Terminated1
DB06643Denosumab1Completed1
DB01234Dexamethasone1Active Not Recruiting1
DB11807Dexmecamylamine1Completed1
DB15130Dexpramipexole1Completed1
DB12301Doravirine1Completed1
DB00470Dronabinol1Withdrawn1
DB15080ELX-021Completed1
DB12243Edaravone1Completed1
DB05187Elafibranor1Recruiting1
DB11574Elbasvir1Completed1
DB06350Elinogrel1Terminated1
DB06210Eltrombopag1Completed1
DB05408Emricasan1Completed1
DB11726Encenicline1Completed1
DB11841Entinostat1Completed1
DB11827Ertugliflozin1Completed1
DB00199Erythromycin1Completed1
DB11823Esketamine1Completed1
DB15170Evobrutinib1Completed1
DB12625Evogliptin1Completed1
DB01276Exenatide1Completed1
DB11808Faldaprevir1Terminated1
DB12500Fedratinib1Completed1
DB12011Fevipiprant1Completed1
DB09279Fimasartan1Completed1
DB08868Fingolimod1Completed1
DB00569Fondaparinux1Completed1
DB12010Fostamatinib1Completed1
DB11796Fostemsavir1Completed1
DB00695Furosemide1Terminated1
DB15097Gefapixant1Completed1
DB11978Glasdegib1Completed1
DB13879Glecaprevir1Completed1
DB14794Glepaglutide1Not Yet Recruiting1
DB06583Glycopyrronium1Completed1
DB11575Grazoprevir1Completed1
DB00956Hydrocodone1Completed2
DB12105Imagabalin1Terminated1
DB14901Inclisiran1Completed1
DB01362Iohexol1Withdrawn1
DB06218Lacosamide1Completed1
DB14814Lanabecestat1Withdrawn1
DB11951Lemborexant1Completed1
DB09078Lenvatinib1Completed1
DB08882Linagliptin1Completed1
DB09198Lobeglitazone1Completed1
DB04871Lorcaserin1Completed1
DB12130Lorlatinib1Recruiting1
DB14808Lumicitabine1Completed1
DB11968MK-71451Terminated1
DB11968MK-71451Withdrawn1
DB06800Methylnaltrexone1Completed1
DB00683Midazolam1Completed1
DB08893Mirabegron1Completed1
DB11792Mirodenafil1Completed1
DB14777Murepavadin1Completed1
DB14011Nabiximols1Withdrawn1
DB15353Nacubactam1Completed1
DB06230Nalmefene1Completed1
DB09049Naloxegol1Completed1
DB15031Nemorexant1Recruiting1
DB00238Nevirapine1Completed1
DB13041Odalasvir1Completed1
DB06670Odanacatib1Completed1
DB11837Osilodrostat1Completed1
DB06635Otamixaban1Completed1
DB14955PF-046348171Completed1
DB14924PF-066516001Recruiting1
DB01229Paclitaxel1Completed1
DB09073Palbociclib1Completed1
DB01267Paliperidone1Completed1
DB06663Pasireotide1Completed1
DB00022Peginterferon alfa-2b1Completed1
DB09122Peginterferon beta-1a1Completed1
DB11759Pevonedistat1Recruiting1
DB00191Phentermine1Completed1
DB13878Pibrentasvir1Completed1
DB04951Pirfenidone1Recruiting1
DB08860Pitavastatin1Completed1
DB11642Pitolisant1Completed1
DB12615Plazomicin1Completed1
DB06809Plerixafor1Completed1
DB08910Pomalidomide1Active Not Recruiting1
DB05154Pretomanid1Recruiting1
DB00468Quinine1Terminated1
DB12935Remogliflozin etabonate1Completed1
DB14898Retagliptin1Completed1
DB11855Revefenacin1Completed1
DB11730Ribociclib1Completed1
DB01045Rifampicin1Completed1
DB00073Rituximab1Active Not Recruiting1
DB06228Rivaroxaban1Completed1
DB12544Rivipansel1Completed1
DB12778Rivipansel1Completed1
DB01098Rosuvastatin1Completed1
DB04847Roxadustat1Completed2
DB06654Safinamide1Completed1
DB13928Semaglutide1Completed1
DB12371Siponimod1Completed1
DB01261Sitagliptin1Completed1
DB11159Sodium sulfide1Terminated1
DB12713Sotagliflozin1Completed1
DB06206Sugammadex1Completed1
DB00864Tacrolimus1Completed1
DB05359Tasimelteon1Completed1
DB09071Tasimelteon1Completed1
DB01606Tazobactam1Completed1
DB14569Tedizolid1Completed1
DB08900Teduglutide1Completed1
DB12095Telotristat ethyl1Completed1
DB14925Tenofovir exalidex1Completed1
DB08880Teriflunomide1Completed1
DB04902Ticagrelor1Completed1
DB08816Ticagrelor1Completed1
DB01409Tiotropium1Completed1
DB00775Tirofiban1Completed1
DB15171Tirzepatide1Completed1
DB08895Tofacitinib1Completed1
DB00214Torasemide1Terminated1
DB12056Trebananib1Completed1
DB06267Udenafil1Completed1
DB12164Varespladib methyl1Terminated1
DB14975Voxelotor1Completed1
DB13090Zidebactam1Completed1
DB11777Cenderitide1 / 2Completed1
DB09261Certoparin1 / 2Completed1
DB00820Tadalafil1 / 2Completed1
DB00820Tadalafil1 / 2Recruiting1
DB05253Telapristone acetate1 / 2Terminated1
DB04876Vildagliptin1 / 2Completed1
DB06151Acetylcysteine2Completed1
DB00640Adenosine2Terminated1
DB08889Carfilzomib2Completed1
DB00565Cisatracurium2Recruiting1
DB15194Cotadutide2Completed1
DB09102Daclatasvir2Withdrawn1
DB01234Dexamethasone2Recruiting1
DB00841Dobutamine2Terminated1
DB12625Evogliptin2Completed1
DB04854Febuxostat2Completed1
DB05059ILY1012Unknown Status1
DB00480Lenalidomide2Completed1
DB15048Licogliflozin2Completed1
DB08882Linagliptin2Completed1
DB00235Milrinone2Terminated1
DB01400Neostigmine2Recruiting1
DB04899Nesiritide2Completed1
DB04899Nesiritide2Terminated1
DB00728Rocuronium2Recruiting1
DB12670Rolofylline2Completed1
DB06290Simeprevir2Withdrawn1
DB01390Sodium bicarbonate2Completed1
DB09153Sodium chloride2Completed1
DB09153Sodium chloride2Terminated1
DB06206Sugammadex2Recruiting1
DB12569Tonapofylline2Terminated1
DB12353Ulodesine2Completed1
DB06779Dalteparin2 / 3Completed1
DB01590Everolimus2 / 3Unknown Status1
DB14901Inclisiran2 / 3Recruiting1
DB05640Tonapofylline2 / 3Completed1
DB12569Tonapofylline2 / 3Completed1
DB06605Apixaban3Recruiting1
DB01076Atorvastatin3Completed2
DB00074Basiliximab3Completed1
DB15200Bixalomer3Completed5
DB08907Canagliflozin3Completed1
DB11723Dutogliptin3Terminated1
DB09038Empagliflozin3Completed1
DB08917Ferric carboxymaltose3Completed1
DB00695Furosemide3Completed2
DB01109Heparin3Recruiting1
DB05059ILY1013Completed3
DB01592Iron3Completed1
DB06792Lanthanum carbonate3Completed1
DB00583Levocarnitine3Terminated1
DB00678Losartan3Completed1
DB00688Mycophenolate mofetil3Completed1
DB00275Olmesartan3Completed1
DB01022Phylloquinone3Recruiting1
DB06228Rivaroxaban3Recruiting1
DB00658Sevelamer3Completed1
DB00877Sirolimus3Completed1
DB01261Sitagliptin3Completed1
DB01261Sitagliptin3Terminated1
DB01390Sodium bicarbonate3Terminated1
DB09153Sodium chloride3Terminated1
DB00864Tacrolimus3Active Not Recruiting1
DB14520Tetraferric tricitrate decahydrate3Completed1
DB04876Vildagliptin3Completed2
DB00437Allopurinol4Completed1
DB00770Alprostadil4Unknown Status1
DB00098Antithymocyte immunoglobulin (rabbit)4Terminated1
DB01053Benzylpenicillin4Terminated1
DB01164Calcium Chloride4Active Not Recruiting1
DB00169Cholecalciferol4Active Not Recruiting1
DB01147Cloxacillin4Terminated1
DB00531Cyclophosphamide4Recruiting1
DB00080Daptomycin4Terminated1
DB08826Deferiprone4Completed1
DB09038Empagliflozin4Completed1
DB01225Enoxaparin4Completed1
DB01590Everolimus4Terminated1
DB00973Ezetimibe4Completed1
DB00569Fondaparinux4Terminated1
DB11728Fondaparinux4Terminated1
DB00996Gabapentin4Terminated1
DB06703Gadobutrol4Completed1
DB00225Gadodiamide4Completed1
DB00789Gadopentetic acid4Completed1
DB09132Gadoteric acid4Completed1
DB00999Hydrochlorothiazide4Completed1
DB01050Ibuprofen4Completed1
DB00702Icodextrin4Active Not Recruiting1
DB00808Indapamide4Completed1
DB01309Insulin Glulisine4Completed1
DB00047Insulin glargine4Completed1
DB01249Iodixanol4Completed1
DB01249Iodixanol4Terminated2
DB01249Iodixanol4Withdrawn1
DB08947Iopamidol4Terminated1
DB09156Iopromide4Withdrawn1
DB09134Ioversol4Terminated1
DB09134Ioversol4Withdrawn1
DB01221Ketamine4Recruiting1
DB06218Lacosamide4Recruiting1
DB04398Lactic acid4Active Not Recruiting1
DB01202Levetiracetam4Completed1
DB01202Levetiracetam4Recruiting1
DB00922Levosimendan4Unknown Status1
DB08882Linagliptin4Active Not Recruiting1
DB09407Magnesium chloride4Active Not Recruiting1
DB00295Morphine4Terminated1
DB00688Mycophenolate mofetil4Terminated1
DB01024Mycophenolic acid4Completed1
DB00607Nafcillin4Terminated1
DB00713Oxacillin4Terminated1
DB00497Oxycodone4Completed1
DB00497Oxycodone4Terminated1
DB01174Phenobarbital4Recruiting1
DB00252Phenytoin4Recruiting1
DB00860Prednisolone4Completed1
DB00073Rituximab4Terminated1
DB00641Simvastatin4Completed1
DB09153Sodium chloride4Active Not Recruiting1
DB00421Spironolactone4Unknown Status1
DB00864Tacrolimus4Completed1
DB00864Tacrolimus4Terminated1
DB00313Valproic acid4Recruiting1
DB00512Vancomycin4Terminated1
DB00945Acetylsalicylic acidNot AvailableRecruiting1
DB00630Alendronic acidNot AvailableCompleted1
DB00125ArginineNot AvailableRecruiting1
DB00612BisoprololNot AvailableRecruiting1
DB01373CalciumNot AvailableCompleted1
DB11093Calcium CitrateNot AvailableCompleted1
DB06724Calcium carbonateNot AvailableCompleted1
DB14733Ceftobiprole medocarilNot AvailableNot Yet Recruiting1
DB00148CreatineNot AvailableCompleted1
DB00016ErythropoietinNot AvailableCompleted1
DB09106Hydroxyethyl StarchNot AvailableCompleted1
DB01362IohexolNot AvailableCompleted1
DB00601LinezolidNot AvailableCompleted1
DB09107Methoxy polyethylene glycol-epoetin betaNot AvailableCompleted1
DB00727NitroglycerinNot AvailableRecruiting1
DB06228RivaroxabanNot AvailableNot Yet Recruiting1
DB01001SalbutamolNot AvailableRecruiting1
DB11094Vitamin DNot AvailableCompleted1
DB00399Zoledronic acidNot AvailableCompleted1