Cold Agglutinin Disease (CAD)
Also known as: Agglutinin Disease, Cold / Cold Agglutinin Disease / Cold type haemolytic anaemia / Cold autoimmune hemolytic anemia / Cold antibody haemolytic anaemia / Cold antibody hemolytic anemia / Cold autoimmune hemolytic anemia (disorder) / Cold type hemolytic anemia
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB14996 | Sutimlimab | A monoclonal antibody directed towards complement subunit C1s used to reduce the need for blood transfusion due to hemolysis in patients with cold agglutinin disease. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB14996 | Sutimlimab | Complement C1s subcomponent | target |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB06769 | Bendamustine | 2 | Completed | 1 |
| DB01257 | Eculizumab | 2 | Completed | 1 |
| DB01073 | Fludarabine | 2 | Completed | 1 |
| DB16200 | Iptacopan | 2 | Active Not Recruiting | 1 |
| DB16694 | Pegcetacoplan | 2 | Completed | 1 |
| DB00073 | Rituximab | 2 | Completed | 2 |
| DB16694 | Pegcetacoplan | 3 | Suspended | 1 |
| DB14996 | Sutimlimab | 3 | Completed | 3 |
| DB00016 | Erythropoietin | Not Available | Recruiting | 1 |
| DB00099 | Filgrastim | Not Available | Recruiting | 1 |
| DB12281 | Luspatercept | Not Available | Recruiting | 1 |
| DB00073 | Rituximab | Not Available | Completed | 1 |
| DB14996 | Sutimlimab | Not Available | Recruiting | 1 |
| DB06534 | Thrombopoietin | Not Available | Recruiting | 1 |