Anemia Associated With Chronic Kidney Disease

Also known as: Anemia in Chronic Kidney Disease / Anaemia in Chronic Kidney Disease / Anemia in Chronic Kidney Diseases / Anemia Associated With Chronic Kidney Disease (CKD) / Anemia caused by Chronic Kidney Disease (CKD) / Anemia co-occurrent and due to chronic kidney disease (disorder)

Drug	Drug Name	Drug Description
DB12255	Vadadustat	An oral hypoxia-inducible factor prolyl-hydroxylase inhibitor used to treat symptomatic anemia associated with chronic kidney disease in adults on chronic maintenance dialysis.

Drug	Drug Name	Target	Type
DB12255	Vadadustat	Egl nine homolog 2	target
DB12255	Vadadustat	Egl nine homolog 3	target
DB12255	Vadadustat	Egl nine homolog 1	target
DB12255	Vadadustat	Hypoxia-inducible factor 1-alpha	target
DB12255	Vadadustat	Endothelial PAS domain-containing protein 1	target
DB12255	Vadadustat	UDP-glucuronosyltransferase 1-1	enzyme
DB12255	Vadadustat	UDP-glucuronosyltransferase 1-7	enzyme
DB12255	Vadadustat	UDP-glucuronosyltransferase 1-8	enzyme
DB12255	Vadadustat	UDP-glucuronosyltransferase 1-9	enzyme
DB12255	Vadadustat	UDP-glucuronosyltransferase 2B7	enzyme
DB12255	Vadadustat	Cytochrome P450 2B6	enzyme
DB12255	Vadadustat	Cytochrome P450 2C8	enzyme
DB12255	Vadadustat	Cytochrome P450 3A4	enzyme
DB12255	Vadadustat	ATP-binding cassette sub-family G member 2	transporter
DB12255	Vadadustat	Solute carrier family 22 member 8	transporter
DB12255	Vadadustat	Solute carrier family 22 member 6	transporter
DB12255	Vadadustat	Serum albumin	carrier
DB12255	Vadadustat	Cytochrome P450 2C9	enzyme

Drug	Drug Name	Phase	Status	Count
DB00012	Darbepoetin alfa	1	Completed	1
DB14985	Enarodustat	1	Completed	1
DB00016	Erythropoietin	1	Completed	1
DB12255	Vadadustat	1	Completed	1
DB04847	Roxadustat	2	Completed	1
DB09107	Methoxy polyethylene glycol-epoetin beta	3	Completed	1
DB04847	Roxadustat	3	Recruiting	1
DB04847	Roxadustat	3	Withdrawn	1
DB12255	Vadadustat	3	Completed	1
DB12208	Iron isomaltoside 1000	Not Available	Completed	1