ESR1 Gene Mutation

Drug	Drug Name	Drug Description
DB06374	Elacestrant	An estrogen receptor antagonist used to treat ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.

Drug	Drug Name	Target	Type
DB06374	Elacestrant	Estrogen receptor alpha	target
DB06374	Elacestrant	Cytochrome P450 3A4	enzyme
DB06374	Elacestrant	Cytochrome P450 2A6	enzyme
DB06374	Elacestrant	Cytochrome P450 2C9	enzyme
DB06374	Elacestrant	Solute carrier organic anion transporter family member 2B1	transporter
DB06374	Elacestrant	P-glycoprotein 1	transporter
DB06374	Elacestrant	ATP-binding cassette sub-family G member 2	transporter

Drug	Drug Name	Phase	Status	Count
DB00675	Tamoxifen	0	Recruiting	1