Metabolite Uridine
- Name
- Uridine
- Description
- Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond. It is one of the five standard nucleosides which make up nucleic acids, the others being adenosine, thymidine, cytidine and guanosine.
- Structure
- Synonyms
- Not Available
- UNII
- Not Available
- CAS number
- 58-96-8
- Weight
- Average: 244.2014
Monoisotopic: 244.069536126 - Chemical Formula
- C9H12N2O6
- InChI Key
- DRTQHJPVMGBUCF-XVFCMESISA-N
- InChI
- InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
- IUPAC Name
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
- SMILES
- OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O
- Reactions
- Uridine triacetate Uridine
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 162.1483971 predictedDarkChem Lite v0.1.0 [M-H]- 162.0889971 predictedDarkChem Lite v0.1.0 [M-H]- 154.5408 predictedDeepCCS 1.0 (2019) [M-H]- 162.1483971 predictedDarkChem Lite v0.1.0 [M-H]- 162.0889971 predictedDarkChem Lite v0.1.0 [M-H]- 154.5408 predictedDeepCCS 1.0 (2019) [M+H]+ 166.2140971 predictedDarkChem Lite v0.1.0 [M+H]+ 163.4639971 predictedDarkChem Lite v0.1.0 [M+H]+ 156.9369 predictedDeepCCS 1.0 (2019) [M+H]+ 166.2140971 predictedDarkChem Lite v0.1.0 [M+H]+ 163.4639971 predictedDarkChem Lite v0.1.0 [M+H]+ 156.9369 predictedDeepCCS 1.0 (2019) [M+Na]+ 162.6416971 predictedDarkChem Lite v0.1.0 [M+Na]+ 162.1919971 predictedDarkChem Lite v0.1.0 [M+Na]+ 162.84947 predictedDeepCCS 1.0 (2019) [M+Na]+ 162.6416971 predictedDarkChem Lite v0.1.0 [M+Na]+ 162.1919971 predictedDarkChem Lite v0.1.0 [M+Na]+ 162.84947 predictedDeepCCS 1.0 (2019) - External Links
- Human Metabolome Database
- HMDB0000296
- KEGG Compound
- C00299
- ChemSpider
- 5807
- BindingDB
- 50088517
- ChEBI
- 16704
- ChEMBL
- CHEMBL100259
- ZINC
- ZINC000002583633
- PharmGKB
- PA130230921
- PDBe Ligand
- URI
- Wikipedia
- Uridine
- Predicted Properties
Property Value Source Water Solubility 135.0 mg/mL ALOGPS logP -1.8 ALOGPS logP -2.4 Chemaxon logS -0.26 ALOGPS pKa (Strongest Acidic) 9.7 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 119.33 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 52.57 m3·mol-1 Chemaxon Polarizability 21.81 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon