Pharmacogenomic Effect/ADR for Citalopram (DBSNPE000047)

Identifier
DBSNPE000047
Drug
Citalopram (DB00215)
Interacting Gene/Enzyme
Glutamate receptor 3
Gene Name
GRIA3
UniProt ID
P42263
Defining Change(s)
G allelers4825476
Allele Name
Not Available
Genotype(s)
(G;A) / (G;G)
Type(s)
ADR Directly Studied
Groups
Not Available
Description
Patients with this genotype have increased frequency of suicidal ideation with citalopram
References
  1. Laje G, Paddock S, Manji H, Rush AJ, Wilson AF, Charney D, McMahon FJ: Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. Am J Psychiatry. 2007 Oct;164(10):1530-8. [PubMed:17898344]