Pharmacogenomic Effect/ADR for Morphine (DBSNPE000078)

Identifier
DBSNPE000078
Drug
Morphine (DB00295)
Interacting Gene/Enzyme
Multidrug resistance protein 1
Gene Name
ABCB1
UniProt ID
P08183
Defining Change(s)
T Allelers1045642
Allele Name
Not Available
Genotype(s)
(C;T) / (T;T)
Type(s)
Effect Directly Studied
Groups
Not Available
Description
Patients with this genotype may have an increased analgesic response to morphine.
References
  1. Campa D, Gioia A, Tomei A, Poli P, Barale R: Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin Pharmacol Ther. 2008 Apr;83(4):559-66. Epub 2007 Sep 26. [PubMed:17898703]