Pharmacogenomic Effect/ADR for Morphine (DBSNPE000079)

Identifier
DBSNPE000079
Drug
Morphine (DB00295)
Interacting Gene/Enzyme
Mu-type opioid receptor
Gene Name
OPRM1
UniProt ID
P35372
Defining Change(s)
A Allelers1799971
Allele Name
Not Available
Genotype(s)
(A;A)
Type(s)
Effect Directly Studied
Groups
Not Available
Description
Patients with this genotype may have an increased analgesic response to morphine.
References
  1. Campa D, Gioia A, Tomei A, Poli P, Barale R: Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin Pharmacol Ther. 2008 Apr;83(4):559-66. Epub 2007 Sep 26. [PubMed:17898703]