Pharmacogenomic Effect/ADR for Valproic acid (DBSNPE000272)

Identifier
DBSNPE000272
Drug
Valproic acid (DB00313)
Interacting Gene/Enzyme
DNA polymerase subunit gamma-1
Gene Name
POLG
UniProt ID
P54098
Defining Change(s)
G > Ars113994095
Allele Name
A467T
Genotype(s)
(A;A) / (A;G)
Type(s)
ADR Directly Studied
Groups
Not Available
Description
The presence of this polymorphism in POLG may indicate an increased risk of liver failure and death when treated with valproic acid.
References
Not Available