Pharmacogenomic Effect/ADR for Chloroquine (DBSNPE000730)

Identifier
DBSNPE000730
Drug
Chloroquine (DB00608)
Interacting Gene/Enzyme
Glucose-6-phosphate 1-dehydrogenase
Gene Name
G6PD
UniProt ID
P11413
Defining Change(s)
1138A->GNot Available
Allele Name
Calvo Mackenna
Genotype(s)
Not Available
Type(s)
ADR Inferred
Groups
G6PD deficiency
Description
Increased risk of hematological effects.
References
  1. Bancone G, Chu CS, Somsakchaicharoen R, Chowwiwat N, Parker DM, Charunwatthana P, White NJ, Nosten FH: Characterization of G6PD genotypes and phenotypes on the northwestern Thailand-Myanmar border. PLoS One. 2014 Dec 23;9(12):e116063. doi: 10.1371/journal.pone.0116063. eCollection 2014. [PubMed:25536053]