Pharmacogenomic Effect/ADR for Aripiprazole (DBSNPE004491)

Identifier
DBSNPE004491
Drug
Aripiprazole (DB01238)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
1758G>Ars5030865
Allele Name
CYP2D6*14A
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer, lower dose requirement.
References
  1. Abilify® (aripiprazole) Tablets[package insert]. Rockville, Maryland: Otsuka America Pharmaceutical, Inc.; 2017. [Link]