Pharmacogenomic Effect/ADR for Aripiprazole (DBSNPE004511)

Identifier
DBSNPE004511
Drug
Aripiprazole (DB01238)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
-1426C>TNot Available
-1235A>GNot Available
-1109C>TNot Available
-1000G>ANot Available
100C>TNot Available
310G>TNot Available
843T>GNot Available
1039C>TNot Available
1661G>CNot Available
2097A>GNot Available
2828delCNot Available
3384A>CNot Available
3582A>GNot Available
4180G>CNot Available
4401C>TNot Available
Allele Name
CYP2D6*100
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer, lower dose requirement.
References
  1. Abilify® (aripiprazole) Tablets[package insert]. Rockville, Maryland: Otsuka America Pharmaceutical, Inc.; 2017. [Link]