Pharmacogenomic Effect/ADR for Cevimeline (DBSNPE004600)

Identifier
DBSNPE004600
Drug
Cevimeline (DB00185)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
-1426C>TNot Available
-1235A>GNot Available
-1000G>ANot Available
100C>TNot Available
310G>TNot Available
CYP2D7 sequence from intron 1 onwardsNot Available
Allele Name
CYP2D6*68A
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor metabolizer, more adverse reactions.
References
  1. Evoxac® capsules (cevimeline hydrochloride)[package insert]. Montvale, New Jersey: Daiichi Pharmaceutical Corporation; 2006. [Link]