Pharmacogenomic Effect/ADR for Gefitinib (DBSNPE004647)

Identifier
DBSNPE004647
Drug
Gefitinib (DB00317)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
CYP2D7/2D6 hybrid gene structureNot Available
Allele Name
CYP2D6*13
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer.
References
  1. Iressa® (gefitinib) tablets[package insert]. Wilmington, Delaware: AstraZeneca Pharmaceuticals LP; 2015. [Link]