Pharmacogenomic Effect/ADR for Perphenazine (DBSNPE004706)

Identifier
DBSNPE004706
Drug
Perphenazine (DB00850)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
1758G>Trs5030865
Allele Name
CYP2D6*8
Genotype(s)
Not Available
Type(s)
ADR Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer, more side effects.
References
  1. Trilafon® (perphenazine) tablets[package insert]. Kenilworth, New Jersey: Schering Corporation; 2002. [Link]