Pharmacogenomic Effect/ADR for Tetrabenazine (DBSNPE004827)

Identifier
DBSNPE004827
Drug
Tetrabenazine (DB04844)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
100C>Trs1065852
-1426C>TNot Available
-1235A>GNot Available
-1000G>ANot Available
73C<TNot Available
1039C>TNot Available
1661G>CNot Available
4180G>CNot Available
Allele Name
CYP2D6*47
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer, lower dose requirement.
References
  1. Xenazine® (tetrabenazine) tablets[package insert]. Deerfield, Illinois: Lundbeck; 2015. [Link]