Pharmacogenomic Effect/ADR for Dapsone (DBSNPE006176)

Identifier
DBSNPE006176
Drug
Dapsone (DB00250)
Interacting Gene/Enzyme
Glucose-6-phosphate 1-dehydrogenase
Gene Name
G6PD
UniProt ID
P11413
Defining Change(s)
826C->TNot Available
Allele Name
Sugao
Genotype(s)
Not Available
Type(s)
ADR Inferred
Groups
G6PD deficiency
Description
Risk of mild hemolysis and hemolytic anemia.
References
  1. Luzzatto L, Seneca E: G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications. Br J Haematol. 2014 Feb;164(4):469-80. doi: 10.1111/bjh.12665. Epub 2013 Dec 28. [PubMed:24372186]
  2. Aczone® (dapsone) Gel[package insert]. Irvine, California: Allergan, Inc.; 2016. [Link]