Pharmacogenomic Effect/ADR for Fentanyl (DBSNPE007009)

Identifier
DBSNPE007009
Drug
Fentanyl (DB00813)
Interacting Gene/Enzyme
Cytochrome P450 3A4
Gene Name
CYP3A4
UniProt ID
P08684
Defining Change(s)
1461_1462insArs67666821
Allele Name
CYP3A4*20
Genotype(s)
Not Available
Type(s)
ADR Inferred
Groups
Non-functional CYP3A4
Description
Poor drug metabolizer, increased adverse drug effects, risk of potentially fatal respiratory depression.
References
  1. FDA Approved Drug Products: Duragesic Transdermal System [Link]