Pharmacogenomic Effect/ADR for Zuclopenthixol (DBSNPE007247)

Identifier
DBSNPE007247
Drug
Zuclopenthixol (DB01624)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
-1426C>TNot Available
-1235A>GNot Available
-1000G>ANot Available
100C>TNot Available
310G>TNot Available
843T>GNot Available
1039C>TNot Available
1661G>CNot Available
2097A>GNot Available
2927_2945delGATCCTACATCCGGATGTGNot Available
3384A>CNot Available
3582A>GNot Available
4180G>CNot Available
4401C>TNot Available
Allele Name
CYP2D6*101
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer.
References
  1. Swen JJ, Nijenhuis M, de Boer A, Grandia L, Maitland-van der Zee AH, Mulder H, Rongen GA, van Schaik RH, Schalekamp T, Touw DJ, van der Weide J, Wilffert B, Deneer VH, Guchelaar HJ: Pharmacogenetics: from bench to byte--an update of guidelines. Clin Pharmacol Ther. 2011 May;89(5):662-73. doi: 10.1038/clpt.2011.34. Epub 2011 Mar 16. [PubMed:21412232]