Enolase

Details

Name

Enolase

Synonyms

2-phospho-D-glycerate hydro-lyase
2-phosphoglycerate dehydratase
4.2.1.11

Gene Name

eno

Organism

Lactobacillus casei (strain BL23)

Amino acid sequence

>lcl|BSEQ0052059|Enolase
MSIITDVLAREVLDSRGNPTVEVELYTEDGGFGRALVPSGASTGEHEAVELRDGDKDRFG
GKGVLKAVGHVNNEIAKAVIGHDVTEQRLIDQTMIDLDGTPNKGKFGANAILGVSLAAAR
AAADEVGLPLYQYLGGPNAHVLPTPMMNVLNGGAHSTNTVDFQEFMIMPVGAKSVREAVR
MGSETFHALQALLKSKGDITAVGDEGGFAPNLKDNEEAFELLVEAIKKAGYKPGDDIALA
FDVAASEMYDAESKTYTTKWSNPDKKYTTEEWTDMIDGYINKYPIVSVEDPIDENDWEGW
QTFTKKMGDKVQIVGDDLFVTNTDYLKKGIDMGVANSILIKLNQIGTLTETFEAIEMAKE
AGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEDQLGAQSL
YKGRKSFYNVKAID

Number of residues

434

Molecular Weight

47110.665

Theoretical pI

Not Available

GO Classification

Functions

magnesium ion binding / phosphopyruvate hydratase activity

Processes

glycolytic process

Components

cell surface / extracellular region / phosphopyruvate hydratase complex

General Function

Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.

Specific Function

Magnesium ion binding

Pfam Domain Function

Enolase_C (PF00113)
Enolase_N (PF03952)

Transmembrane Regions

Not Available

Cellular Location

Cytoplasm

Gene sequence

>lcl|BSEQ0052060|Enolase (eno)
ATGTCTATCATTACTGATGTATTGGCACGCGAAGTCTTAGACTCCCGTGGCAACCCTACT
GTTGAAGTTGAATTGTACACTGAAGACGGCGGCTTTGGCCGTGCGTTGGTACCATCAGGT
GCTTCAACCGGTGAACACGAAGCCGTTGAACTTCGTGATGGTGACAAGGATCGTTTTGGC
GGCAAGGGTGTTTTGAAGGCCGTTGGTCATGTGAACAACGAAATCGCTAAGGCGGTTATT
GGCCATGACGTGACTGAACAACGCCTGATTGACCAAACCATGATTGACCTTGACGGTACC
CCGAACAAGGGCAAGTTTGGCGCCAATGCTATCTTGGGTGTTTCCTTGGCTGCAGCCCGT
GCTGCTGCTGATGAAGTTGGCCTGCCATTGTATCAATATCTTGGCGGCCCGAATGCCCAC
GTTCTGCCAACGCCAATGATGAACGTCCTCAATGGTGGTGCACACTCAACTAACACCGTT
GACTTCCAGGAATTCATGATCATGCCTGTTGGCGCTAAGAGCGTTCGTGAAGCTGTTCGG
ATGGGTTCAGAAACCTTCCATGCTTTACAGGCACTGTTGAAGAGTAAAGGCGACATCACC
GCTGTTGGTGATGAAGGCGGCTTTGCCCCGAACTTGAAGGATAACGAAGAAGCCTTCGAA
CTTCTTGTTGAAGCAATCAAGAAAGCTGGCTACAAGCCAGGCGACGACATTGCTTTGGCC
TTTGACGTTGCTGCTTCAGAAATGTACGATGCCGAGAGCAAGACATACACAACCAAGTGG
TCTAACCCTGACAAGAAGTACACCACTGAAGAATGGACCGACATGATTGATGGTTACATT
AACAAGTACCCAATCGTTTCTGTTGAAGATCCTATCGACGAAAACGACTGGGAAGGCTGG
CAGACATTCACCAAGAAGATGGGCGACAAAGTCCAAATCGTTGGTGATGATCTGTTTGTT
ACCAACACCGACTACCTGAAGAAGGGTATCGATATGGGTGTTGCTAACTCCATCCTGATC
AAGCTGAACCAGATCGGTACATTGACCGAAACCTTCGAAGCCATCGAAATGGCTAAAGAA
GCTGGTTACACAGCTGTTGTTTCACATCGTTCCGGTGAAACTGAAGATACAACGATTGCT
GACTTGGTTGTTGCAACCAACGCTGGCCAGATCAAGACTGGTTCAATGAGCCGGACAGAT
CGTATCGCTAAGTACAACCAGTTAATGCGGATCGAAGATCAACTGGGTGCACAATCCTTG
TACAAGGGCCGCAAGTCCTTCTACAATGTGAAAGCAATCGACTAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	B3WCW7
UniProtKB Entry Name	ENO_LACCB

General References

Not Available

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB09325	Sodium fluoride	approved	unknown	inhibitor	Details