NH(3)-dependent NAD(+) synthetase

Details

Name

NH(3)-dependent NAD(+) synthetase

Synonyms

• 6.3.1.5

Gene Name

nadE

Organism

Helicobacter pylori (strain ATCC 700392 / 26695)

Amino acid sequence

>lcl|BSEQ0011262|NH(3)-dependent NAD(+) synthetase
MQKDYQKLIVYLCDFLEKEVQKRGFKKVVYGLSGGLDSAVVGVLCQKVFKENAHALLMPS
SVSMPENKTDALNLCEKFSIPYTEYSIAPYDAIFSSHFKDASLTRKGNFCARLRMAFLYD
YSLKSDSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELARRLNIPKKILNK
PPSADLFVGQSDEKDLGYPYSVIDPLLKDIEALFQTKPIDTETLAQLGYDEILVKNITSR
IQKNAFKLELPAIAKRFNPE

Number of residues

260

Molecular Weight

29268.575

Theoretical pI

8.16

GO Classification

Functions

ATP binding / NAD+ synthase (glutamine-hydrolyzing) activity / NAD+ synthase activity

Processes

NAD biosynthetic process

General Function

Nad+ synthase activity

Specific Function

Not Available

Pfam Domain Function

• NAD_synthase (PF02540)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0011263|NH(3)-dependent NAD(+) synthetase (nadE)
ATGCAAAAAGATTACCAAAAACTCATCGTTTATTTATGCGATTTTTTAGAAAAAGAAGTG
CAAAAACGCGGCTTTAAAAAAGTCGTTTACGGGCTGAGCGGGGGGCTAGATAGCGCGGTC
GTTGGGGTGCTGTGTCAAAAAGTTTTTAAAGAAAACGCTCATGCCCTTTTAATGCCCTCT
TCAGTCTCTATGCCAGAAAATAAAACAGACGCCCTAAATTTGTGCGAAAAATTTTCTATC
CCTTATACAGAATATTCTATCGCTCCCTATGACGCCATCTTTAGCTCTCACTTTAAAGAC
GCAAGCCTTACTAGGAAGGGGAATTTTTGCGCAAGATTGCGCATGGCTTTTTTATACGAT
TATTCTTTAAAAAGCGATTCTTTAGTCATTGGCACGAGCAATAAAAGCGAAAGAATGCTA
GGCTATGGCACTTTATTTGGGGATTTGGCGTGCGCGATTAACCCGATTGGGGAATTATTT
AAAACCGAAGTTTATGAACTCGCTCGCCGTTTAAATATCCCTAAAAAGATTTTAAATAAG
CCCCCTAGCGCAGATTTATTTGTGGGGCAAAGCGATGAAAAAGATTTGGGCTATCCTTAT
AGCGTGATCGATCCTTTATTGAAGGATATTGAAGCGTTGTTTCAAACAAAGCCCATTGAT
ACAGAAACGCTCGCTCAATTAGGCTATGATGAAATTTTAGTGAAAAACATCACAAGCCGT
ATCCAAAAAAACGCTTTTAAATTAGAATTACCCGCCATCGCCAAACGATTTAACCCTGAA
TGA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	O25096
UniProtKB Entry Name	NADE_HELPY
GenBank Protein ID	2313426
GenBank Gene ID	AE000511

General References

1. Tomb JF, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA, Nelson K, Quackenbush J, Zhou L, Kirkness EF, Peterson S, Loftus B, Richardson D, Dodson R, Khalak HG, Glodek A, McKenney K, Fitzegerald LM, Lee N, Adams MD, Hickey EK, Berg DE, Gocayne JD, Utterback TR, Peterson JD, Kelley JM, Cotton MD, Weidman JM, Fujii C, Bowman C, Watthey L, Wallin E, Hayes WS, Borodovsky M, Karp PD, Smith HO, Fraser CM, Venter JC: The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature. 1997 Aug 7;388(6642):539-47. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB04099	Deamido-Nad+	experimental	unknown		Details