Knob-associated histidine-rich protein

Details

Name
Knob-associated histidine-rich protein
Synonyms
  • HRPI
Gene Name
Not Available
Organism
Plasmodium falciparum
Amino acid sequence
>lcl|BSEQ0051390|Knob-associated histidine-rich protein
MKSFKNKNTLRRKKAFPVFTKILLVSFLVWVLKCSNNCNNGNGSGDSFDFRNKRTLAQKQ
HEHHHHHHHQHQHQHQAPHQAHHHHHHGEVNHQAPQVHQQVHGQDQAHHHHHHHHHQLQP
QQLQGTVANPPSNEPVVKTQVFREARPGGGFKAYEEKYESKHYKLKENVVDGKKDCDEKY
EAANYAFSEECPYTVNDYSQENGPNIFALRKRFPLGMNDEDEEGKEALAIKDKLPGGLDE
YQNQLYGICNETCTTCGPAAIDYVPADAPNGYAYGGSAHDGSHGNLRGHGNKGSEGYGYE
APYNPGFNGAPGSNGMQNYVPPHGAGYSAPYGVPHGAAHGSRYSSFSSVNKYGKHGDEKH
HSSKKHEGNDGEGEKKKKSKKHKDHDGEKKKSKKHKDNEDAESVKSKKHKSHDCEKKKSK
KHKDNEDAESVKSKKSVKEKGEKHNGKKPCSKKTNEENKNKEKTNNLKSDGSK
Number of residues
473
Molecular Weight
53191.4
Theoretical pI
Not Available
GO Classification
Components
extracellular region
General Function
KAHRP might mimick human histidine-rich glycoproteins to anchor host thrombospondin or a parasite analog in a binding complex with the endothelial cell receptor.
Specific Function
Not Available
Pfam Domain Function
Not Available
Transmembrane Regions
Not Available
Cellular Location
Secreted
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP13817
UniProtKB Entry NameKNOB_PLAFA
General References
  1. Ellis J, Irving DO, Wellems TE, Howard RJ, Cross GA: Structure and expression of the knob-associated histidine-rich protein of Plasmodium falciparum. Mol Biochem Parasitol. 1987 Nov;26(1-2):203-14. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB11638Artenimolapproved, experimental, investigationalunknownligandDetails