Endoglucanase C
Details
- Name
- Endoglucanase C
- Synonyms
- 3.2.1.4
- Cellulase C
- Endo-1,4-beta-glucanase C
- Gene Name
- cenC
- Organism
- Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547)
- Amino acid sequence
>lcl|BSEQ0011930|Endoglucanase C MVSRRSSQARGALTAVVATLALALAGSGTALAASPIGEGTFDDGPEGWVAYGTDGPLDTS TGALCVAVPAGSAQYGVGVVLNGVAIEEGTTYTLRYTATASTDVTVRALVGQNGAPYGTV LDTSPALTSEPRQVTETFTASATYPATPAADDPEGQIAFQLGGFSADAWTFCLDDVALDS EVELLPHTSFAESLGPWSLYGTSEPVFADGRMCVDLPGGQGNPWDAGLVYNGVPVGEGES YVLSFTASATPDMPVRVLVGEGGGAYRTAFEQGSAPLTGEPATREYAFTSNLTFPPDGDA PGQVAFHLGKAGAYEFCISQVSLTTSATPPPGYEPDTGPRVRVNQVGYLPFGPKRATLVT DAAEPVAWELRDADGVVVADGTSEPRGVEPSAAQAVHVLDFSDVTTQGAGYTLVADGETS RPFDIDGDLYQQLRYDALNYFYLARSGTEIEADVVGEEYAREAGHVGVAPNQGDTDVPCI GPRDYYDGWTCDYRLDVSGGWYDAGDHGKYVVNGGIAVGQLLQTYERALHAGTADALADG TLDVPEHGNDVPDVLDEARWELEWMLSMIVPEGEYAGMVHHKVHDEGWTGLPLLPADDPQ ARSLHRPSTAATLNLSAVAAQGARLLEPYDPQLAQTLLEAARTTWAAAQEHPALYAPGEA GADGGGAYNDSQVADEFYWAAAELYLTTGEDAFATAVTTSPLHTADVFTADGFGWGSVAA LGRLDLATVPNELPGLDAVQSSVVEGAQEYLAAQAGQGFGSLYSPPGGEYVWGSSSQVAN NLVVVATAYDLTGDERFRAATLEGLDYLFGRNALNQSYVTGWGEVASHQQHSRWFAHQLD PSLPSPPPGSLAGGPNSQAATWDPTTKAAFPDGCAPSACYVDEIQAWSTNELTVNWNSAL SWVASWVADQGSAEPVPTAPVVTRQPVDATVALGADATFTAEASGVPAPTVRWQVRAGRG WKDVAGATGTTLTVRATARTDGTRYRAVFTNAAGSVESAVVRLTVERAAPVVTQHPADVR ARVGTRAVFRAAADGYPTPCVVWQVRWGGGSWRPIPWATSTTLSVPVTVLAAGTEYRAVF TNAVGTAATEPAELAVQRPRS
- Number of residues
- 1101
- Molecular Weight
- 115215.07
- Theoretical pI
- 4.11
- GO Classification
- Functionscellulase activityProcessescellulose catabolic process
- General Function
- Cellulase activity
- Specific Function
- The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0011931|Endoglucanase C (cenC) GTGGTTTCTCGCAGGTCATCACAGGCGCGCGGCGCGCTCACGGCCGTCGTCGCGACGCTC GCCCTCGCGCTCGCCGGGAGCGGCACCGCGCTCGCCGCGTCGCCGATCGGGGAGGGAACG TTCGACGACGGGCCCGAGGGGTGGGTCGCGTACGGCACCGACGGCCCCCTCGACACGAGC ACGGGCGCGCTGTGCGTCGCCGTGCCGGCCGGATCCGCGCAGTACGGCGTCGGCGTCGTG CTCAACGGCGTCGCGATCGAGGAAGGGACCACCTACACGCTCCGGTACACCGCGACGGCC TCGACCGACGTCACCGTGCGGGCGCTCGTCGGGCAGAACGGCGCCCCCTACGGCACCGTG CTCGACACGAGCCCGGCCCTGACGTCCGAGCCGCGGCAGGTGACCGAGACGTTCACGGCC TCGGCGACGTACCCCGCGACACCCGCCGCCGACGACCCCGAGGGGCAGATCGCCTTCCAG CTCGGCGGGTTCAGCGCCGACGCGTGGACGTTCTGCCTCGACGACGTCGCGCTCGACTCC GAGGTCGAGCTCCTGCCGCACACGTCGTTCGCCGAGTCGCTCGGCCCGTGGTCCCTGTAC GGCACGAGCGAGCCGGTGTTCGCCGACGGCCGGATGTGCGTCGACCTGCCCGGCGGGCAG GGCAACCCCTGGGACGCGGGCCTCGTCTACAACGGCGTTCCCGTCGGCGAGGGCGAGAGC TACGTCCTGTCGTTCACCGCGAGCGCGACGCCCGACATGCCGGTGCGCGTGCTCGTCGGC GAGGGCGGCGGCGCCTACCGGACCGCCTTCGAGCAGGGGTCGGCACCGCTGACCGGCGAG CCCGCGACCCGCGAGTACGCGTTCACCTCGAACCTGACGTTCCCGCCCGACGGCGACGCA CCCGGCCAGGTCGCGTTCCACCTCGGCAAGGCCGGTGCGTACGAGTTCTGCATCTCGCAG GTGTCGCTCACCACCTCGGCGACGCCGCCGCCCGGGTACGAGCCCGACACCGGCCCGCGC GTGCGGGTCAACCAGGTGGGCTACCTGCCGTTCGGGCCGAAGCGCGCCACCCTCGTCACC GACGCGGCCGAGCCGGTCGCGTGGGAGCTGCGCGACGCCGACGGCGTGGTCGTCGCCGAC GGGACCAGCGAGCCGCGCGGCGTCGAGCCGTCGGCCGCGCAGGCGGTGCACGTGCTCGAC TTCTCCGACGTCACGACGCAGGGCGCGGGGTACACGCTCGTCGCCGACGGCGAGACGAGC CGCCCCTTCGACATCGACGGCGACCTGTACCAGCAGCTCCGGTACGACGCGCTCAACTAC TTCTACCTCGCGCGCTCCGGCACCGAGATCGAGGCGGACGTGGTCGGCGAGGAGTACGCC CGCGAGGCGGGCCACGTCGGCGTCGCGCCCAACCAGGGCGACACCGACGTGCCGTGCATC GGCCCGCGCGACTACTACGACGGCTGGACGTGCGACTACCGGCTCGACGTGAGCGGCGGC TGGTACGACGCCGGCGACCACGGCAAGTACGTCGTCAACGGCGGCATCGCGGTCGGGCAG CTCCTGCAGACGTACGAGCGGGCGCTGCACGCGGGCACCGCCGACGCGCTCGCGGACGGC ACCCTCGACGTGCCCGAGCACGGCAACGACGTGCCCGACGTCCTGGACGAGGCGCGCTGG GAGCTCGAGTGGATGCTCTCGATGATCGTGCCCGAGGGGGAGTACGCGGGGATGGTGCAC CACAAGGTGCACGACGAGGGCTGGACCGGGCTGCCGCTGCTGCCGGCCGACGACCCGCAG GCGCGCTCGCTGCACCGGCCGTCGACCGCGGCGACGCTCAACCTGTCCGCCGTCGCGGCG CAGGGGGCGCGCCTGCTCGAGCCGTACGACCCGCAGCTCGCGCAGACGCTGCTGGAGGCG GCACGCACGACCTGGGCTGCGGCCCAGGAGCACCCGGCGCTGTACGCCCCGGGCGAGGCC GGCGCGGACGGCGGTGGCGCGTACAACGACTCCCAGGTGGCCGACGAGTTCTACTGGGCG GCCGCCGAGCTCTACCTGACGACGGGCGAGGACGCGTTCGCCACCGCGGTGACGACCTCG CCGCTGCACACCGCGGACGTGTTCACCGCGGACGGGTTCGGCTGGGGGAGCGTCGCCGCG CTGGGTCGCCTCGACCTCGCGACGGTGCCGAACGAGCTGCCGGGTCTCGACGCGGTGCAA TCGTCGGTCGTCGAGGGGGCGCAGGAGTACCTCGCGGCGCAGGCGGGGCAGGGATTCGGC TCGCTGTACTCCCCGCCCGGCGGCGAGTACGTCTGGGGCTCGAGCTCGCAGGTCGCGAAC AACCTCGTCGTCGTCGCGACCGCGTACGACCTCACGGGCGACGAGCGGTTCCGGGCGGCG ACGCTCGAGGGGCTCGACTACCTGTTCGGCCGCAACGCGCTCAACCAGTCGTACGTGACG GGCTGGGGCGAGGTCGCCTCGCACCAGCAGCACAGCCGGTGGTTCGCGCACCAGCTCGAC CCGTCGCTCCCGAGCCCGCCGCCCGGCTCGCTCGCGGGCGGCCCGAACTCGCAGGCCGCG ACGTGGGACCCGACGACGAAGGCGGCGTTCCCCGACGGCTGCGCGCCGTCCGCGTGCTAC GTCGACGAGATCCAGGCGTGGTCGACGAACGAGCTCACCGTCAACTGGAACTCCGCGCTG TCCTGGGTCGCCTCGTGGGTGGCCGACCAGGGCTCGGCCGAGCCGGTGCCGACGGCGCCG GTGGTGACGCGGCAGCCCGTCGACGCGACCGTCGCGCTCGGTGCCGACGCCACGTTCACC GCGGAGGCGAGCGGCGTGCCCGCGCCGACCGTCCGGTGGCAGGTGCGGGCCGGCCGCGGC TGGAAGGACGTCGCCGGCGCGACCGGGACCACGCTCACGGTCCGCGCGACCGCCCGCACC GACGGCACGCGGTACCGGGCGGTGTTCACCAACGCGGCCGGCTCGGTCGAGAGCGCCGTC GTGCGGCTCACCGTCGAGCGCGCGGCACCCGTCGTGACGCAGCACCCGGCCGACGTCCGG GCACGGGTCGGCACGCGTGCCGTGTTCCGCGCGGCCGCCGACGGGTACCCCACGCCCTGC GTCGTGTGGCAGGTGCGGTGGGGCGGCGGGAGCTGGCGGCCGATCCCGTGGGCCACCTCG ACGACGCTCTCCGTGCCGGTCACGGTGCTCGCGGCGGGCACGGAGTACCGCGCGGTGTTC ACCAACGCCGTCGGCACCGCGGCGACCGAGCCTGCCGAGCTCGCCGTGCAGCGTCCGCGC AGCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P14090 UniProtKB Entry Name GUNC_CELFA GenBank Gene ID X57858 - General References
- Coutinho JB, Moser B, Kilburn DG, Warren RA, Miller RC Jr: Nucleotide sequence of the endoglucanase C gene (cenC) of Cellulomonas fimi, its high-level expression in Escherichia coli, and characterization of its products. Mol Microbiol. 1991 May;5(5):1221-33. [Article]
- Moser B, Gilkes NR, Kilburn DG, Warren RA, Miller RC Jr: Purification and characterization of endoglucanase C of Cellulomonas fimi, cloning of the gene, and analysis of in vivo transcripts of the gene. Appl Environ Microbiol. 1989 Oct;55(10):2480-7. [Article]
- Coutinho JB, Gilkes NR, Warren RA, Kilburn DG, Miller RC Jr: The binding of Cellulomonas fimi endoglucanase C (CenC) to cellulose and Sephadex is mediated by the N-terminal repeats. Mol Microbiol. 1992 May;6(9):1243-52. [Article]
- Bateman A, Eddy SR, Chothia C: Members of the immunoglobulin superfamily in bacteria. Protein Sci. 1996 Sep;5(9):1939-41. [Article]
- Johnson PE, Joshi MD, Tomme P, Kilburn DG, McIntosh LP: Structure of the N-terminal cellulose-binding domain of Cellulomonas fimi CenC determined by nuclear magnetic resonance spectroscopy. Biochemistry. 1996 Nov 12;35(45):14381-94. [Article]