Tryptophan synthase alpha chain
Details
- Name
- Tryptophan synthase alpha chain
- Synonyms
- 4.2.1.20
- Gene Name
- trpA
- Organism
- Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
- Amino acid sequence
>lcl|BSEQ0011224|Tryptophan synthase alpha chain MTTLEAFAKARSEGRAALIPYLTAGFPSREGFLQAVEEVLPYADLLEIGLPYSDPLGDGP VIQRASELALRKGMSVQGALELVREVRALTEKPLFLMTYLNPVLAWGPERFFGLFKQAGA TGVILPDLPPDEDPGLVRLAQEIGLETVFLLAPTSTDARIATVVRHATGFVYAVSVTGVT GMRERLPEEVKDLVRRIKARTALPVAVGFGVSGKATAAQAAVADGVVVGSALVRALEEGR SLAPLLQEIRQGLQRLEANPGLKESSKKPLS
- Number of residues
- 271
- Molecular Weight
- 28936.25
- Theoretical pI
- 6.09
- GO Classification
- Functionstryptophan synthase activity
- General Function
- Tryptophan synthase activity
- Specific Function
- The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
- Pfam Domain Function
- Trp_syntA (PF00290)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0011225|Tryptophan synthase alpha chain (trpA) GTGACCACCCTCGAGGCCTTCGCCAAGGCCCGGTCCGAGGGCCGGGCCGCCCTCATCCCT TACCTCACCGCGGGCTTCCCCAGCCGGGAGGGCTTTTTGCAGGCGGTGGAGGAGGTCCTC CCCTATGCCGACCTTCTGGAGATCGGCCTCCCCTACTCCGACCCCCTGGGGGACGGCCCC GTGATCCAGCGGGCAAGCGAACTGGCCCTGAGGAAGGGGATGAGCGTCCAAGGCGCTTTG GAGCTCGTCCGCGAGGTGCGCGCCCTCACGGAGAAACCCCTCTTCCTCATGACCTACCTG AACCCCGTCCTGGCCTGGGGGCCGGAGCGCTTCTTCGGCCTCTTCAAGCAGGCGGGGGCC ACGGGGGTGATCCTTCCCGACCTTCCCCCCGACGAGGACCCAGGCCTCGTGCGCCTCGCC CAGGAGATCGGCCTGGAGACGGTCTTCCTTCTCGCCCCCACCTCCACGGACGCCCGCATC GCCACCGTGGTCCGCCACGCCACGGGCTTCGTCTACGCCGTCTCCGTCACCGGGGTCACG GGGATGCGGGAAAGGCTTCCCGAGGAGGTCAAGGACCTGGTGCGGCGCATCAAGGCCAGG ACCGCCCTCCCCGTGGCCGTGGGCTTCGGGGTTTCCGGCAAGGCCACGGCCGCGCAGGCG GCGGTGGCGGACGGGGTGGTGGTGGGAAGCGCCTTGGTCCGGGCCTTGGAGGAGGGGAGG TCCCTTGCGCCCCTTCTCCAGGAGATCCGCCAGGGCCTCCAGCGCCTCGAGGCCAACCCC GGCCTGAAGGAAAGCTCAAAGAAGCCGTTGTCCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P16608 UniProtKB Entry Name TRPA_THET2 GenBank Protein ID 155133 GenBank Gene ID M32108 - General References
- Koyama Y, Furukawa K: Cloning and sequence analysis of tryptophan synthetase genes of an extreme thermophile, Thermus thermophilus HB27: plasmid transfer from replica-plated Escherichia coli recombinant colonies to competent T. thermophilus cells. J Bacteriol. 1990 Jun;172(6):3490-5. [Article]
- Henne A, Bruggemann H, Raasch C, Wiezer A, Hartsch T, Liesegang H, Johann A, Lienard T, Gohl O, Martinez-Arias R, Jacobi C, Starkuviene V, Schlenczeck S, Dencker S, Huber R, Klenk HP, Kramer W, Merkl R, Gottschalk G, Fritz HJ: The genome sequence of the extreme thermophile Thermus thermophilus. Nat Biotechnol. 2004 May;22(5):547-53. Epub 2004 Apr 4. [Article]