Transcobalamin-1
Details
- Name
- Transcobalamin-1
- Synonyms
- Haptocorrin
- HC
- Protein R
- TC I
- TC-1
- TC1
- TCI
- Transcobalamin I
- Gene Name
- TCN1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0016043|Transcobalamin-1 MRQSHQLPLVGLLLFSFIPSQLCEICEVSEENYIRLKPLLNTMIQSNYNRGTSAVNVVLS LKLVGIQIQTLMQKMIQQIKYNVKSRLSDVSSGELALIILALGVCRNAEENLIYDYHLID KLENKFQAEIENMEAHNGTPLTNYYQLSLDVLALCLFNGNYSTAEVVNHFTPENKNYYFG SQFSVDTGAMAVLALTCVKKSLINGQIKADEGSLKNISIYTKSLVEKILSEKKENGLIGN TFSTGEAMQALFVSSDYYNENDWNCQQTLNTVLTEISQGAFSNPNAAAQVLPALMGKTFL DINKDSSCVSASGNFNISADEPITVTPPDSQSYISVNYSVRINETYFTNVTVLNGSVFLS VMEKAQKMNDTIFGFTMEERSWGPYITCIQGLCANNNDRTYWELLSGGEPLSQGAGSYVV RNGENLEVRWSKY
- Number of residues
- 433
- Molecular Weight
- 48206.32
- Theoretical pI
- 4.68
- GO Classification
- Functionscobalamin bindingProcessescobalamin metabolic process / cobalamin transport / cobalt ion transport / small molecule metabolic process / vitamin metabolic process / water-soluble vitamin metabolic processComponentsextracellular region / extracellular space
- General Function
- Cobalamin binding
- Specific Function
- Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0016044|Transcobalamin-1 (TCN1) ATGAGACAGTCACACCAGCTGCCCCTAGTGGGGCTCTTACTGTTTTCTTTTATTCCAAGC CAACTATGCGAGATTTGTGAGGTAAGTGAAGAAAACTACATCCGCCTAAAACCTCTGTTG AATACAATGATCCAGTCAAACTATAACAGGGGAACCAGCGCTGTCAATGTTGTGTTGTCC CTCAAACTTGTTGGAATCCAGATCCAAACCCTGATGCAAAAGATGATCCAACAAATCAAA TACAATGTGAAAAGCAGATTGTCAGATGTAAGCTCGGGAGAGCTTGCCTTGATTATACTG GCTTTGGGAGTATGTCGTAACGCTGAGGAAAACTTAATATATGATTACCACCTGATCGAC AAGCTAGAAAATAAATTCCAAGCAGAAATTGAAAATATGGAAGCACACAATGGCACTCCC CTGACTAACTACTACCAGCTCAGCCTGGACGTTTTGGCCTTGTGTCTGTTCAATGGGAAC TACTCAACCGCCGAAGTTGTCAACCACTTCACTCCTGAAAATAAAAACTATTATTTTGGT AGCCAGTTCTCAGTAGATACTGGTGCAATGGCTGTCCTGGCTCTGACCTGTGTGAAGAAG AGTCTAATAAATGGGCAGATCAAAGCAGATGAAGGCAGTTTAAAGAACATCAGTATTTAT ACAAAGTCACTGGTAGAAAAGATTCTGTCTGAGAAAAAAGAAAATGGTCTCATTGGAAAC ACATTTAGCACAGGAGAAGCCATGCAGGCCCTCTTTGTATCATCAGACTATTATAATGAA AATGACTGGAATTGCCAACAAACTCTGAATACAGTGCTCACGGAAATTTCTCAAGGAGCA TTCAGCAATCCAAACGCTGCAGCCCAGGTCTTACCTGCCCTGATGGGAAAGACCTTCTTG GATATTAACAAAGACTCTTCTTGCGTCTCTGCTTCAGGTAACTTCAACATCTCCGCTGAT GAGCCTATAACTGTGACACCTCCTGACTCACAATCATATATCTCCGTCAATTACTCTGTG AGAATCAATGAAACATATTTCACCAATGTCACTGTGCTAAATGGTTCTGTCTTCCTCAGT GTGATGGAGAAAGCCCAGAAAATGAATGATACTATATTTGGTTTCACAATGGAGGAGCGC TCATGGGGGCCCTATATCACCTGTATTCAGGGCCTATGTGCCAACAATAATGACAGAACC TACTGGGAACTTCTGAGTGGAGGCGAACCACTGAGCCAAGGAGCTGGTAGTTACGTTGTC CGCAATGGAGAAAACTTGGAGGTTCGCTGGAGCAAATACTAA
- Chromosome Location
- 11
- Locus
- 11q11-q12
- External Identifiers
Resource Link UniProtKB ID P20061 UniProtKB Entry Name TCO1_HUMAN GenBank Protein ID 307479 GenBank Gene ID J05068 GenAtlas ID TCN1 HGNC ID HGNC:11652 - General References
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