Amicyanin

Details

Name
Amicyanin
Synonyms
  • ami
Gene Name
mauC
Organism
Paracoccus denitrificans
Amino acid sequence
>lcl|BSEQ0011934|Amicyanin
MISATKIRSCLAACVLAAFGATGALADKATIPSESPFAAAEVADGAIVVDIAKMKYETPE
LHVKVGDTVTWINREAMPHNVHFVAGVLGEAALKGPMMKKEQAYSLTFTEAGTYDYHCTP
HPFMRGKVVVE
Number of residues
131
Molecular Weight
13983.11
Theoretical pI
6.67
GO Classification
Functions
copper ion binding / electron carrier activity
Processes
oxidation-reduction process
Components
periplasmic space
General Function
Electron carrier activity
Specific Function
Primary acceptor of electrons from methylamine dehydrogenase. Passes those electrons on either a soluble cytochrome c or to pseudoazurin.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Periplasm
Gene sequence
>lcl|BSEQ0005382|396 bp
ATGATTTCTGCGACCAAGATCCGCTCGTGCCTGGCGGCCTGCGTCCTGGCGGCATTCGGC
GCGACGGGCGCCCTGGCCGACAAGGCGACGATCCCCTCGGAAAGCCCCTTTGCCGCCGCC
GAGGTGGCCGATGGCGCCATCGTCGTCGACATCGCCAAGATGAAATACGAAACCCCCGAA
CTTCATGTGAAGGTCGGCGACACCGTCACCTGGATCAACCGCGAGGCGATGCCGCACAAT
GTCCATTTCGTCGCCGGCGTGCTGGGCGAGGCGGCGTTGAAAGGCCCGATGATGAAGAAG
GAGCAGGCCTATTCCCTGACCTTCACCGAGGCCGGCACCTATGACTATCACTGCACCCCG
CATCCCTTCATGCGCGGCAAGGTCGTCGTCGAGTAG
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP22364
UniProtKB Entry NameAMCY_PARDE
GenBank Gene IDX55665
General References
  1. van Spanning RJ, Wansell CW, Reijnders WN, Oltmann LF, Stouthamer AH: Mutagenesis of the gene encoding amicyanin of Paracoccus denitrificans and the resultant effect on methylamine oxidation. FEBS Lett. 1990 Nov 26;275(1-2):217-20. [Article]
  2. Husain M, Davidson VL, Smith AJ: Properties of Paracoccus denitrificans amicyanin. Biochemistry. 1986 May 6;25(9):2431-6. [Article]
  3. Chen L, Durley R, Poliks BJ, Hamada K, Chen Z, Mathews FS, Davidson VL, Satow Y, Huizinga E, Vellieux FM, et al.: Crystal structure of an electron-transfer complex between methylamine dehydrogenase and amicyanin. Biochemistry. 1992 Jun 2;31(21):4959-64. [Article]
  4. Chen L, Durley RC, Mathews FS, Davidson VL: Structure of an electron transfer complex: methylamine dehydrogenase, amicyanin, and cytochrome c551i. Science. 1994 Apr 1;264(5155):86-90. [Article]
  5. Cunane LM, Chen ZW, Durley RC, Mathews FS: X-ray structure of the cupredoxin amicyanin, from Paracoccus denitrificans, refined at 1.31 A resolution. Acta Crystallogr D Biol Crystallogr. 1996 Jul 1;52(Pt 4):676-86. [Article]
  6. Zhu Z, Cunane LM, Chen Z, Durley RC, Mathews FS, Davidson VL: Molecular basis for interprotein complex-dependent effects on the redox properties of amicyanin. Biochemistry. 1998 Dec 8;37(49):17128-36. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB02467L-methionine (S)-S-oxideexperimentalunknownDetails
DB08646TRW3-(2-AMINO-3-HYDROXY-PROPYL)-6-(N'-CYCLOHEXYL-HYDRAZINO)OCTAHYDRO-INDOL-7-OLexperimentalunknownDetails