Glycine cleavage system H protein, mitochondrial
Details
- Name
- Glycine cleavage system H protein, mitochondrial
- Synonyms
- Lipoic acid-containing protein
- Gene Name
- GCSH
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0011658|Glycine cleavage system H protein, mitochondrial MALRVVRSVRALLCTLRAVPSPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWV TTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEV TEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE
- Number of residues
- 173
- Molecular Weight
- 18884.37
- Theoretical pI
- 4.56
- GO Classification
- Functionsaminomethyltransferase activityProcessescellular nitrogen compound metabolic process / glycine catabolic process / glycine decarboxylation via glycine cleavage system / glyoxylate metabolic process / methylation / small molecule metabolic processComponentsglycine cleavage complex / mitochondrial matrix / mitochondrion
- General Function
- Aminomethyltransferase activity
- Specific Function
- The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
- Pfam Domain Function
- GCV_H (PF01597)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion
- Gene sequence
>lcl|BSEQ0011659|Glycine cleavage system H protein, mitochondrial (GCSH) ATGGCGCTGCGAGTGGTGCGGAGCGTGCGGGCCCTGCTCTGCACCCTGCGCGCGGTCCCG TCACCCGCCGCGCCCTGCCCGCCGAGGCCCTGGCAGCTGGGGGTGGGCGCCGTCCGTACG CTGCGCACTGGACCCGCTCTGCTCTCGGTGCGTAAATTCACAGAGAAACACGAATGGGTA ACAACAGAAAATGGCATTGGAACAGTGGGAATCAGCAATTTTGCACAGGAAGCGTTGGGA GATGTTGTTTATTGTAGTCTCCCTGAAGTTGGGACAAAATTGAACAAACAAGATGAGTTT GGTGCTTTGGAAAGTGTGAAAGCTGCTAGTGAACTCTATTCTCCTTTATCAGGAGAAGTA ACTGAAATTAATGAAGCTCTTGCAGAAAATCCAGGACTTGTAAACAAATCTTGTTATGAA GATGGTTGGCTGATCAAGATGACACTGAGTAACCCTTCAGAACTAGATGAACTTATGAGT GAAGAAGCATATGAGAAATACATAAAATCTATTGAGGAGTGA
- Chromosome Location
- 16
- Locus
- 16q23.2
- External Identifiers
Resource Link UniProtKB ID P23434 UniProtKB Entry Name GCSH_HUMAN GenBank Protein ID 184348 GenBank Gene ID M69175 GenAtlas ID GCSH HGNC ID HGNC:4208 - General References
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