Glucose-1-phosphate cytidylyltransferase
Details
- Name
- Glucose-1-phosphate cytidylyltransferase
- Synonyms
- 2.7.7.33
- CDP-glucose pyrophosphorylase
- Gene Name
- rfbF
- Organism
- Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
- Amino acid sequence
>lcl|BSEQ0011932|Glucose-1-phosphate cytidylyltransferase MKAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVHGIKDFIICCGYKGYVI KEYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGDSSMTGGRLKRVAEYVKDD EAFLFTYGDGVADLDIKATIDFHKAHGKKATLTATFPPGRFGALDIRAGQVRSFQEKPKG DGAMINGGFFVLNPSVIDLIDNDATTWEQEPLMTLAQQGELMAFEHPGFWQPMDTLRDKV YLEGLWEKGKAPWKTWE
- Number of residues
- 257
- Molecular Weight
- 29035.34
- Theoretical pI
- 6.61
- GO Classification
- Functionsglucose-1-phosphate cytidylyltransferase activity / metal ion binding / nucleotide bindingProcessesO antigen biosynthetic process
- General Function
- Nucleotide binding
- Specific Function
- Involved in the biosynthesis of the tyvelose, a 3,6-dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate (By similarity).
- Pfam Domain Function
- NTP_transferase (PF00483)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0011933|Glucose-1-phosphate cytidylyltransferase (rfbF) ATGAAAGCGGTCATCCTGGCTGGTGGACTTGGTACCAGACTAAGTGAAGAAACAATTGTA AAACCAAAACCGATGGTAGAAATTGGTGGCAAGCCTATTCTTTGGCACATTATGAAAATG TATTCTGTGCATGGTATCAAGGATTTTATTATCTGCTGTGGTTATAAAGGATATGTGATT AAAGAATATTTTGCGAACTACTTCCTTCACATGTCAGATGTAACATTCCATATGGCTGAA AACCGTATGGAAGTTCACCATAAACGTGTTGAACCATGGAATGTCACATTGGTTGATACG GGTGATTCTTCAATGACTGGTGGTCGTCTGAAACGTGTTGCTGAATACGTAAAAGATGAC GAGGCTTTCCTGTTTACTTATGGTGATGGCGTTGCCGACCTTGATATCAAAGCGACTATC GATTTCCATAAGGCTCACGGTAAGAAAGCGACTTTAACAGCTACTTTTCCACCAGGACGC TTTGGCGCATTAGATATCCGAGCTGGTCAGGTCCGGTCATTCCAGGAAAAACCGAAAGGC GATGGGGCAATGATCAATGGTGGTTTCTTTGTGTTGAATCCATCGGTTATCGATCTCATC GATAACGATGCAACAACCTGGGAACAAGAGCCATTAATGACATTGGCACAACAGGGGGAG TTAATGGCTTTTGAACACCCAGGTTTCTGGCAGCCGATGGATACCCTACGTGATAAAGTT TACCTCGAAGGGCTGTGGGAAAAAGGTAAAGCTCCGTGGAAAACCTGGGAGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P26396 UniProtKB Entry Name RFBF_SALTY GenBank Gene ID X56793 - General References
- Jiang XM, Neal B, Santiago F, Lee SJ, Romana LK, Reeves PR: Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2). Mol Microbiol. 1991 Mar;5(3):695-713. [Article]
- McClelland M, Sanderson KE, Spieth J, Clifton SW, Latreille P, Courtney L, Porwollik S, Ali J, Dante M, Du F, Hou S, Layman D, Leonard S, Nguyen C, Scott K, Holmes A, Grewal N, Mulvaney E, Ryan E, Sun H, Florea L, Miller W, Stoneking T, Nhan M, Waterston R, Wilson RK: Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature. 2001 Oct 25;413(6858):852-6. [Article]