L-rhamnose isomerase
Details
- Name
- L-rhamnose isomerase
- Synonyms
- 5.3.1.14
- Gene Name
- rhaA
- Organism
- Escherichia coli (strain K12)
- Amino acid sequence
>lcl|BSEQ0011347|L-rhamnose isomerase MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQ ATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVE WAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPS VMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVG SNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVL LDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAEL RKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLESVRAYEKEILSRRG
- Number of residues
- 419
- Molecular Weight
- 47198.95
- Theoretical pI
- 5.57
- GO Classification
- Functionsidentical protein binding / L-rhamnose isomerase activity / manganese ion bindingProcessesL-lyxose metabolic process / rhamnose catabolic processComponentscytoplasm
- General Function
- Manganese ion binding
- Specific Function
- Not Available
- Pfam Domain Function
- RhaA (PF06134)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0011348|L-rhamnose isomerase (rhaA) ATGACCACTCAACTGGAACAGGCCTGGGAGCTAGCGAAACAGCGTTTCGCGGCGGTGGGG ATTGATGTCGAGGAGGCGCTGCGCCAACTTGATCGTTTACCCGTTTCAATGCACTGCTGG CAGGGCGATGATGTTTCCGGTTTTGAAAACCCGGAAGGTTCGCTGACCGGGGGGATTCAG GCCACAGGCAATTATCCGGGCAAAGCGCGTAATGCCAGTGAGCTACGTGCCGATCTGGAA CAGGCTATGCGGCTGATTCCGGGGCCGAAACGGCTTAATTTACATGCCATCTATCTGGAA TCAGATACGCCAGTCTCGCGCGACCAGATCAAACCAGAGCACTTCAAAAACTGGGTTGAA TGGGCGAAAGCCAATCAGCTCGGTCTGGATTTTAACCCCTCCTGCTTTTCGCATCCGCTA AGCGCCGATGGCTTTACGCTTTCCCATGCCGACGACAGCATTCGCCAGTTCTGGATTGAT CACTGCAAAGCCAGCCGTCGCGTTTCGGCCTATTTTGGCGAGCAACTCGGCACACCATCG GTGATGAACATCTGGATCCCGGATGGTATGAAAGATATCACCGTTGACCGTCTCGCCCCG CGTCAGCGTCTGCTGGCAGCACTGGATGAGGTGATCAGCGAGAAGCTAAACCCTGCGCAC CATATCGACGCCGTTGAGAGCAAATTGTTTGGCATTGGCGCAGAGAGCTACACGGTTGGC TCCAATGAGTTTTACATGGGGTATGCCACCAGCCGCCAGACTGCGCTGTGCCTGGACGCC GGGCACTTCCACCCGACTGAAGTGATTTCCGACAAGATTTCCGCCGCCATGCTGTATGTG CCGCAGTTGCTGCTGCACGTCAGCCGTCCGGTTCGCTGGGACAGCGATCACGTAGTGCTG CTGGATGATGAAACCCAGGCAATTGCCAGTGAGATTGTGCGTCACGATCTGTTTGACCGG GTGCATATCGGCCTTGACTTCTTCGATGCCTCTATCAACCGCATTGCCGCGTGGGTCATT GGTACACGCAATATGAAAAAAGCCCTGCTGCGTGCGTTGCTGGAACCTACCGCTGAGCTG CGCAAGCTGGAAGCGGCGGGCGATTACACTGCGCGTCTGGCACTGCTGGAAGAGCAGAAA TCGTTGCCGTGGCAGGCGGTCTGGGAAATGTATTGCCAACGTCACGATACGCCAGCAGGT AGCGAATGGCTGGAGAGCGTGCGGGCTTATGAGAAAGAAATTTTGAGTCGCCGCGGGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P32170 UniProtKB Entry Name RHAA_ECOLI GenBank Protein ID 396680 GenBank Gene ID X60472 - General References
- Moralejo P, Egan SM, Hidalgo E, Aguilar J: Sequencing and characterization of a gene cluster encoding the enzymes for L-rhamnose metabolism in Escherichia coli. J Bacteriol. 1993 Sep;175(17):5585-94. [Article]
- Plunkett G 3rd, Burland V, Daniels DL, Blattner FR: Analysis of the Escherichia coli genome. III. DNA sequence of the region from 87.2 to 89.2 minutes. Nucleic Acids Res. 1993 Jul 25;21(15):3391-8. [Article]
- Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y: The complete genome sequence of Escherichia coli K-12. Science. 1997 Sep 5;277(5331):1453-62. [Article]
- Riley M, Abe T, Arnaud MB, Berlyn MK, Blattner FR, Chaudhuri RR, Glasner JD, Horiuchi T, Keseler IM, Kosuge T, Mori H, Perna NT, Plunkett G 3rd, Rudd KE, Serres MH, Thomas GH, Thomson NR, Wishart D, Wanner BL: Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. 2006 Jan 5;34(1):1-9. Print 2006. [Article]
- Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T: Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol Syst Biol. 2006;2:2006.0007. Epub 2006 Feb 21. [Article]
- Egan SM, Schleif RF: A regulatory cascade in the induction of rhaBAD. J Mol Biol. 1993 Nov 5;234(1):87-98. [Article]
- Holcroft CC, Egan SM: Roles of cyclic AMP receptor protein and the carboxyl-terminal domain of the alpha subunit in transcription activation of the Escherichia coli rhaBAD operon. J Bacteriol. 2000 Jun;182(12):3529-35. [Article]
- Korndorfer IP, Fessner WD, Matthews BW: The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution. J Mol Biol. 2000 Jul 21;300(4):917-33. [Article]