40S ribosomal protein S19

Details

Name
40S ribosomal protein S19
Synonyms
  • Small ribosomal subunit protein eS19
Gene Name
RPS19
Organism
Humans
Amino acid sequence
>lcl|BSEQ0049932|40S ribosomal protein S19
MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAAST
ARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGG
RKLTPQGQRDLDRIAGQVAAANKKH
Number of residues
145
Molecular Weight
16060.44
Theoretical pI
Not Available
GO Classification
Functions
fibroblast growth factor binding / protein homodimerization activity / protein kinase binding / RNA binding / structural constituent of ribosome
Processes
erythrocyte differentiation / maturation of SSU-rRNA / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / monocyte chemotaxis / negative regulation of respiratory burst involved in inflammatory response / Notch signaling pathway / nuclear-transcribed mRNA catabolic process, nonsense-mediated decay / nucleolus organization / positive regulation of cellular component movement / positive regulation of respiratory burst involved in inflammatory response / protein tetramerization / response to extracellular stimulus / ribosomal small subunit assembly / ribosomal small subunit biogenesis / rRNA processing / SRP-dependent cotranslational protein targeting to membrane / translation / translational initiation / viral transcription
Components
cytoplasm / cytosol / cytosolic small ribosomal subunit / extracellular exosome / extracellular matrix / focal adhesion / membrane / nucleolus / nucleoplasm / ribosome
General Function
Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
Specific Function
Fibroblast growth factor binding
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Nucleus
Gene sequence
>lcl|BSEQ0049933|40S ribosomal protein S19 (RPS19)
ATGCCTGGAGTTACTGTAAAAGACGTGAACCAGCAGGAGTTCGTCAGAGCTCTGGCAGCC
TTCCTCAAAAAGTCCGGGAAGCTGAAAGTCCCCGAATGGGTGGATACCGTCAAGCTGGCC
AAGCACAAAGAGCTTGCTCCCTACGATGAGAACTGGTTCTACACGCGAGCTGCTTCCACA
GCGCGGCACCTGTACCTCCGGGGTGGCGCTGGGGTTGGCTCCATGACCAAGATCTATGGG
GGACGTCAGAGAAACGGCGTCATGCCCAGCCACTTCAGCCGAGGCTCCAAGAGTGTGGCC
CGCCGGGTCCTCCAAGCCCTGGAGGGGCTGAAAATGGTGGAAAAGGACCAAGATGGCGGC
CGCAAACTGACACCTCAGGGACAAAGAGATCTGGACAGAATCGCCGGACAGGTGGCAGCT
GCCAACAAGAAGCATTAG
Chromosome Location
19
Locus
19q13.2
External Identifiers
ResourceLink
UniProtKB IDP39019
UniProtKB Entry NameRS19_HUMAN
HGNC IDHGNC:10402
General References
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB11638Artenimolapproved, experimental, investigationalunknownligandDetails