Bacitracin transport permease protein BcrC

Details

Name
Bacitracin transport permease protein BcrC
Synonyms
Not Available
Gene Name
bcrC
Organism
Bacillus licheniformis
Amino acid sequence
>lcl|BSEQ0052066|Bacitracin transport permease protein BcrC
MSFSELNIDAFRFINDLGKEYSMLNPVVYFLAEYMMYFLALGLVVYWLTRTTKNRLMVIY
AVIAFVVAEILGKIMGSLHSNYQPFATLPNVNKLIEHEIDNSFPSDHTILFFSIGFLIFL
FHKKTGWLWLVLAFAVGISRIWSGVHYPLDVAAGALLGVLSALFVFWTAPKLSFIHQMLS
LYEKVEQRIVPSKNKSNDKSKNF
Number of residues
203
Molecular Weight
23274.21
Theoretical pI
Not Available
GO Classification
Functions
undecaprenyl-diphosphatase activity
Processes
response to antibiotic
Components
integral component of membrane / plasma membrane
General Function
Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic; probably responsible for the translocation of the substrate across the membrane.
Specific Function
Undecaprenyl-diphosphatase activity
Pfam Domain Function
Transmembrane Regions
27-47 56-76 103-121 126-143 149-169
Cellular Location
Cell membrane
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP42334
UniProtKB Entry NameBCRC_BACLI
General References
  1. Podlesek Z, Comino A, Herzog-Velikonja B, Zgur-Bertok D, Komel R, Grabnar M: Bacillus licheniformis bacitracin-resistance ABC transporter: relationship to mammalian multidrug resistance. Mol Microbiol. 1995 Jun;16(5):969-76. doi: 10.1111/j.1365-2958.1995.tb02322.x. [Article]
  2. Konz D, Klens A, Schorgendorfer K, Marahiel MA: The bacitracin biosynthesis operon of Bacillus licheniformis ATCC 10716: molecular characterization of three multi-modular peptide synthetases. Chem Biol. 1997 Dec;4(12):927-37. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00626Bacitracinapproved, vet_approvedunknownsubstrateDetails