Nicotinate-nucleotide adenylyltransferase
Details
- Name
- Nicotinate-nucleotide adenylyltransferase
- Synonyms
- 2.7.7.18
- Deamido-NAD(+) diphosphorylase
- Deamido-NAD(+) pyrophosphorylase
- NaMN adenylyltransferase
- Nicotinate mononucleotide adenylyltransferase
- yqeJ
- Gene Name
- nadD
- Organism
- Bacillus subtilis (strain 168)
- Amino acid sequence
>lcl|BSEQ0016528|Nicotinate-nucleotide adenylyltransferase MKKIGIFGGTFDPPHNGHLLMANEVLYQAGLDEIWFMPNQIPPHKQNEDYTDSFHRVEML KLAIQSNPSFKLELVEMEREGPSYTFDTVSLLKQRYPNDQLFFIIGADMIEYLPKWYKLD ELLNLIQFIGVKRPGFHVETPYPLLFADVPEFEVSSTMIRERFKSKKPTDYLIPDKVKKY VEENGLYES
- Number of residues
- 189
- Molecular Weight
- 22156.34
- Theoretical pI
- 5.11
- GO Classification
- FunctionsATP binding / nicotinate-nucleotide adenylyltransferase activityProcessesNAD biosynthetic process
- General Function
- Nicotinate-nucleotide adenylyltransferase activity
- Specific Function
- Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
- Pfam Domain Function
- CTP_transf_like (PF01467)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0016529|Nicotinate-nucleotide adenylyltransferase (nadD) ATGAAGAAAATCGGAATTTTCGGAGGCACGTTTGACCCTCCGCATAATGGTCACCTCTTA ATGGCGAATGAGGTGCTGTACCAGGCGGGGCTTGATGAAATTTGGTTTATGCCTAATCAA ATTCCGCCGCATAAACAGAACGAAGACTATACCGACAGCTTTCATCGCGTGGAAATGCTA AAGCTTGCAATTCAATCTAATCCGTCCTTTAAGCTGGAGCTTGTTGAAATGGAAAGAGAA GGGCCATCATATACCTTTGATACCGTTTCTTTACTGAAGCAGCGTTATCCAAATGATCAG CTGTTCTTTATTATCGGCGCTGATATGATTGAATATTTGCCGAAATGGTATAAGCTGGAC GAGCTGCTGAACCTCATTCAATTTATTGGAGTAAAGCGCCCCGGTTTTCATGTTGAAACC CCTTATCCGCTTCTCTTTGCAGACGTTCCGGAATTTGAGGTATCATCAACTATGATAAGG GAACGGTTTAAAAGCAAGAAGCCCACTGACTACTTAATCCCTGATAAAGTGAAGAAGTAT GTAGAGGAGAATGGTTTATATGAATCGTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P54455 UniProtKB Entry Name NADD_BACSU GenBank Protein ID 1303791 GenBank Gene ID D84432 - General References
- Mizuno M, Masuda S, Takemaru K, Hosono S, Sato T, Takeuchi M, Kobayashi Y: Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the Bacillus subtilis genome containing the skin element and many sporulation genes. Microbiology. 1996 Nov;142 ( Pt 11):3103-11. [Article]
- Kunst F, Ogasawara N, Moszer I, Albertini AM, Alloni G, Azevedo V, Bertero MG, Bessieres P, Bolotin A, Borchert S, Borriss R, Boursier L, Brans A, Braun M, Brignell SC, Bron S, Brouillet S, Bruschi CV, Caldwell B, Capuano V, Carter NM, Choi SK, Cordani JJ, Connerton IF, Cummings NJ, Daniel RA, Denziot F, Devine KM, Dusterhoft A, Ehrlich SD, Emmerson PT, Entian KD, Errington J, Fabret C, Ferrari E, Foulger D, Fritz C, Fujita M, Fujita Y, Fuma S, Galizzi A, Galleron N, Ghim SY, Glaser P, Goffeau A, Golightly EJ, Grandi G, Guiseppi G, Guy BJ, Haga K, Haiech J, Harwood CR, Henaut A, Hilbert H, Holsappel S, Hosono S, Hullo MF, Itaya M, Jones L, Joris B, Karamata D, Kasahara Y, Klaerr-Blanchard M, Klein C, Kobayashi Y, Koetter P, Koningstein G, Krogh S, Kumano M, Kurita K, Lapidus A, Lardinois S, Lauber J, Lazarevic V, Lee SM, Levine A, Liu H, Masuda S, Mauel C, Medigue C, Medina N, Mellado RP, Mizuno M, Moestl D, Nakai S, Noback M, Noone D, O'Reilly M, Ogawa K, Ogiwara A, Oudega B, Park SH, Parro V, Pohl TM, Portelle D, Porwollik S, Prescott AM, Presecan E, Pujic P, Purnelle B, Rapoport G, Rey M, Reynolds S, Rieger M, Rivolta C, Rocha E, Roche B, Rose M, Sadaie Y, Sato T, Scanlan E, Schleich S, Schroeter R, Scoffone F, Sekiguchi J, Sekowska A, Seror SJ, Serror P, Shin BS, Soldo B, Sorokin A, Tacconi E, Takagi T, Takahashi H, Takemaru K, Takeuchi M, Tamakoshi A, Tanaka T, Terpstra P, Togoni A, Tosato V, Uchiyama S, Vandebol M, Vannier F, Vassarotti A, Viari A, Wambutt R, Wedler H, Weitzenegger T, Winters P, Wipat A, Yamamoto H, Yamane K, Yasumoto K, Yata K, Yoshida K, Yoshikawa HF, Zumstein E, Yoshikawa H, Danchin A: The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature. 1997 Nov 20;390(6657):249-56. [Article]
- Olland AM, Underwood KW, Czerwinski RM, Lo MC, Aulabaugh A, Bard J, Stahl ML, Somers WS, Sullivan FX, Chopra R: Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase. J Biol Chem. 2002 Feb 1;277(5):3698-707. Epub 2001 Nov 9. [Article]