60S ribosomal protein L37

Details

Name
60S ribosomal protein L37
Synonyms
  • G1.16
Gene Name
RPL37
Organism
Humans
Amino acid sequence
>lcl|BSEQ0012673|60S ribosomal protein L37
MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTG
TGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS
Number of residues
97
Molecular Weight
11077.81
Theoretical pI
12.26
GO Classification
Functions
metal ion binding / RNA binding / rRNA binding / structural constituent of ribosome
Processes
cellular protein metabolic process / gene expression / nuclear-transcribed mRNA catabolic process, nonsense-mediated decay / SRP-dependent cotranslational protein targeting to membrane / translation / translational elongation / translational initiation / translational termination / viral life cycle / viral process / viral transcription
Components
cytosol / cytosolic large ribosomal subunit
General Function
Structural constituent of ribosome
Specific Function
Binds to the 23S rRNA.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0012674|60S ribosomal protein L37 (RPL37)
ATGACGAAGGGAACGTCATCGTTTGGAAAGCGTCGCAATAAGACGCACACGTTGTGCCGC
CGCTGTGGCTCTAAGGCCTACCACCTTCAGAAGTCGACCTGTGGCAAATGTGGCTACCCT
GCCAAGCGCAAGAGAAAGTATAACTGGAGTGCCAAGGCTAAAAGACGAAATACCACCGGA
ACTGGTCGAATGAGGCACCTAAAAATTGTATACCGCAGATTCAGGCATGGATTCCGTGAA
GGAACAACACCTAAACCCAAGAGGGCAGCTGTTGCAGCATCCAGTTCATCTTAA
Chromosome Location
5
Locus
5p13
External Identifiers
ResourceLink
UniProtKB IDP61927
UniProtKB Entry NameRL37_HUMAN
GenBank Protein ID461232
GenBank Gene IDD23661
HGNC IDHGNC:10347
General References
  1. Barnard GF, Staniunas RJ, Puder M, Steele GD Jr, Chen LB: Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain. Biochim Biophys Acta. 1994 Aug 2;1218(3):425-8. [Article]
  2. Su S, Bird RC: Cell cycle, differentiation and tissue-independent expression of ribosomal protein L37. Eur J Biochem. 1995 Sep 15;232(3):789-97. [Article]
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  6. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC: A map of 75 human ribosomal protein genes. Genome Res. 1998 May;8(5):509-23. [Article]
  7. Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell. 2008 Aug 8;31(3):438-48. doi: 10.1016/j.molcel.2008.07.007. [Article]
  8. Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal. 2009 Aug 18;2(84):ra46. doi: 10.1126/scisignal.2000007. [Article]
  9. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M: Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science. 2009 Aug 14;325(5942):834-40. doi: 10.1126/science.1175371. Epub 2009 Jul 16. [Article]
  10. Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal. 2010 Jan 12;3(104):ra3. doi: 10.1126/scisignal.2000475. [Article]
  11. Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J: Initial characterization of the human central proteome. BMC Syst Biol. 2011 Jan 26;5:17. doi: 10.1186/1752-0509-5-17. [Article]
  12. Rigbolt KT, Prokhorova TA, Akimov V, Henningsen J, Johansen PT, Kratchmarova I, Kassem M, Mann M, Olsen JV, Blagoev B: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal. 2011 Mar 15;4(164):rs3. doi: 10.1126/scisignal.2001570. [Article]
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB04602PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATEexperimentalunknownDetails
DB04805Virginiamycin S1experimentalunknownDetails
DB07374AnisomycinexperimentalunknownDetails
DB02494(S)-3-phenyllactic acidexperimentalunknownDetails
DB08437PuromycinexperimentalunknownDetails