60S ribosomal protein L23

Details

Name
60S ribosomal protein L23
Synonyms
  • 60S ribosomal protein L17
Gene Name
RPL23
Organism
Humans
Amino acid sequence
>lcl|BSEQ0020709|60S ribosomal protein L23
MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDM
VMATVKKGKPELRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGP
VAKECADLWPRIASNAGSIA
Number of residues
140
Molecular Weight
14865.335
Theoretical pI
11.2
GO Classification
Functions
large ribosomal subunit rRNA binding / poly(A) RNA binding / structural constituent of ribosome
Processes
cellular protein metabolic process / gene expression / nuclear-transcribed mRNA catabolic process, nonsense-mediated decay / ribosomal protein import into nucleus / SRP-dependent cotranslational protein targeting to membrane / translation / translational elongation / translational initiation / translational termination / viral life cycle / viral process / viral transcription
Components
cytoplasm / cytosol / cytosolic large ribosomal subunit / extracellular exosome / focal adhesion / membrane / nucleolus / ribosome
General Function
Structural constituent of ribosome
Specific Function
Not Available
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0020710|60S ribosomal protein L23 (RPL23)
ATGTCGAAGCGAGGACGTGGTGGGTCCTCTGGTGCGAAATTCCGGATTTCCTTGGGTCTT
CCGGTAGGAGCTGTAATCAATTGTGCTGACAACACAGGAGCCAAAAACCTGTATATCATC
TCCGTGAAGGGGATCAAGGGACGGCTGAACAGACTTCCCGCTGCTGGTGTGGGTGACATG
GTGATGGCCACAGTCAAGAAAGGCAAACCAGAGCTCAGAAAAAAGGTACATCCAGCAGTG
GTCATTCGACAACGAAAGTCATACCGTAGAAAAGATGGCGTGTTTCTTTATTTTGAAGAT
AATGCAGGAGTCATAGTGAACAATAAAGGCGAGATGAAAGGTTCTGCCATTACAGGACCA
GTAGCAAAGGAGTGTGCAGACTTGTGGCCCCGGATTGCATCCAATGCTGGCAGCATTGCA
TGA
Chromosome Location
17
Locus
17q
External Identifiers
ResourceLink
UniProtKB IDP62829
UniProtKB Entry NameRL23_HUMAN
GenBank Protein ID36126
GenBank Gene IDX52839
HGNC IDHGNC:10316
General References
  1. Herault Y, Michel D, Chatelain G, Brun G: cDNA and predicted amino acid sequences of the human ribosomal protein genes rpS12 and rpL17. Nucleic Acids Res. 1991 Jul 25;19(14):4001. [Article]
  2. Berchtold MW, Berger MC: Isolation and analysis of a human cDNA highly homologous to the yeast gene encoding L17A ribosomal protein. Gene. 1991 Jun 30;102(2):283-8. [Article]
  3. Yoshihama M, Uechi T, Asakawa S, Kawasaki K, Kato S, Higa S, Maeda N, Minoshima S, Tanaka T, Shimizu N, Kenmochi N: The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. Genome Res. 2002 Mar;12(3):379-90. [Article]
  4. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [Article]
  5. Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Nat Biotechnol. 2005 Jan;23(1):94-101. Epub 2004 Dec 12. [Article]
  6. Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell. 2008 Aug 8;31(3):438-48. doi: 10.1016/j.molcel.2008.07.007. [Article]
  7. Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J: Initial characterization of the human central proteome. BMC Syst Biol. 2011 Jan 26;5:17. doi: 10.1186/1752-0509-5-17. [Article]
  8. Bian Y, Song C, Cheng K, Dong M, Wang F, Huang J, Sun D, Wang L, Ye M, Zou H: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics. 2014 Jan 16;96:253-62. doi: 10.1016/j.jprot.2013.11.014. Epub 2013 Nov 22. [Article]
  9. Vaca Jacome AS, Rabilloud T, Schaeffer-Reiss C, Rompais M, Ayoub D, Lane L, Bairoch A, Van Dorsselaer A, Carapito C: N-terminome analysis of the human mitochondrial proteome. Proteomics. 2015 Jul;15(14):2519-24. doi: 10.1002/pmic.201400617. Epub 2015 Jun 8. [Article]
  10. Anger AM, Armache JP, Berninghausen O, Habeck M, Subklewe M, Wilson DN, Beckmann R: Structures of the human and Drosophila 80S ribosome. Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB07374AnisomycinexperimentalunknownDetails
DB02494(S)-3-phenyllactic acidexperimentalunknownDetails
DB08437PuromycinexperimentalunknownDetails