Actin, alpha skeletal muscle
Details
- Name
- Actin, alpha skeletal muscle
- Synonyms
- ACTA
- Alpha-actin-1
- Gene Name
- ACTA1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0016680|Actin, alpha skeletal muscle MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEA QSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREK MTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRL DLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEK SYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNV MSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWIT KQEYDEAGPSIVHRKCF
- Number of residues
- 377
- Molecular Weight
- 42050.67
- Theoretical pI
- 5.05
- GO Classification
- FunctionsADP binding / ATP binding / myosin binding / structural constituent of cytoskeletonProcessescell growth / mesenchyme migration / muscle contraction / muscle filament sliding / positive regulation of gene expression / response to extracellular stimulus / response to lithium ion / response to mechanical stimulus / response to steroid hormone / skeletal muscle fiber adaptation / skeletal muscle fiber development / skeletal muscle thin filament assemblyComponentsactin cytoskeleton / actin filament / blood microparticle / cell body / cytosol / extracellular exosome / extracellular space / filopodium / lamellipodium / sarcomere / stress fiber / striated muscle thin filament
- General Function
- Structural constituent of cytoskeleton
- Specific Function
- Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
- Pfam Domain Function
- Actin (PF00022)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0016681|Actin, alpha skeletal muscle (ACTA1) ATGTGCGACGAAGACGAGACCACCGCCCTCGTGTGCGACAATGGCTCCGGCCTGGTGAAA GCCGGCTTCGCCGGGGATGACGCCCCTAGGGCCGTGTTCCCGTCCATCGTGGGCCGCCCC CGACACCAGGGCGTCATGGTCGGTATGGGTCAGAAAGATTCCTACGTGGGCGACGAGGCT CAGAGCAAGAGAGGTATCCTGACCCTGAAGTACCCTATCGAGCACGGCATCATCACCAAC TGGGATGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTTCGCGTGGCTCCC GAGGAGCACCCCACCCTGCTCACCGAGGCCCCCCTCAATCCCAAGGCCAACCGCGAGAAG ATGACCCAGATCATGTTTGAGACCTTCAACGTGCCCGCCATGTACGTGGCCATCCAGGCC GTGCTGTCCCTCTACGCCTCCGGCAGGACCACCGGCATCGTGCTGGACTCCGGCGACGGC GTCACCCACAACGTGCCCATTTATGAGGGCTACGCGCTGCCGCACGCCATCATGCGCCTG GACCTGGCGGGCCGCGATCTCACCGACTACCTGATGAAGATCCTCACTGAGCGTGGCTAC TCCTTCGTGACCACAGCTGAGCGCGAGATCGTGCGCGACATCAAGGAGAAGCTGTGCTAC GTGGCCCTGGACTTCGAGAACGAGATGGCGACGGCCGCCTCCTCCTCCTCCCTGGAAAAG AGCTACGAGCTGCCAGACGGGCAGGTCATCACCATCGGCAACGAGCGCTTCCGCTGCCCG GAGACGCTCTTCCAGCCCTCCTTCATCGGTATGGAGTCGGCGGGCATTCACGAGACCACC TACAACAGCATCATGAAGTGTGACATCGACATCAGGAAGGACCTGTATGCCAACAACGTC ATGTCGGGGGGCACCACGATGTACCCTGGGATCGCTGACCGCATGCAGAAAGAGATCACC GCGCTGGCACCCAGCACCATGAAGATCAAGATCATCGCCCCGCCGGAGCGCAAATACTCG GTGTGGATCGGCGGCTCCATCCTGGCCTCGCTGTCCACCTTCCAGCAGATGTGGATCACC AAGCAGGAGTACGACGAGGCCGGCCCTTCCATCGTCCACCGCAAATGCTTCTAG
- Chromosome Location
- 1
- Locus
- 1q42.13-q42.2
- External Identifiers
Resource Link UniProtKB ID P68133 UniProtKB Entry Name ACTS_HUMAN GenBank Protein ID 178029 GenBank Gene ID J00068 GenAtlas ID ACTA1 HGNC ID HGNC:129 - General References
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Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details DB02772 Sucrose approved, experimental, investigational unknown Details DB03021 Ulapualide A experimental unknown Details DB03616 Kabiramide C experimental unknown Details DB03850 Jaspisamide A experimental unknown Details DB03903 Tmr experimental unknown Details DB04151 1-Methylhistidine experimental unknown Details DB04395 Phosphoaminophosphonic Acid-Adenylate Ester experimental unknown Details DB04629 Aplyronine A experimental unknown Details DB04774 Reidispongiolide A experimental unknown Details DB04775 Reidispongiolide C experimental unknown Details DB04783 Sphinxolide B experimental unknown Details DB08080 Latrunculin B experimental unknown Details DB02621 Latrunculin A experimental unknown inhibitor Details