Cathepsin L1

Details

Name
Cathepsin L1
Synonyms
  • 3.4.22.15
Gene Name
Not Available
Organism
Fasciola hepatica
Amino acid sequence
>lcl|BSEQ0052092|Cathepsin L1
AVPDKIDPRESGYVTGVKDQ
Number of residues
20
Molecular Weight
2174.385
Theoretical pI
Not Available
GO Classification
Functions
cysteine-type peptidase activity
Components
lysosome
General Function
Thiol protease that assists the parasite in burrowing through the gut wall and liver of its mammalian host.
Specific Function
Cysteine-type peptidase activity
Pfam Domain Function
Not Available
Transmembrane Regions
Not Available
Cellular Location
Lysosome
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ09093
UniProtKB Entry NameCATL1_FASHE
General References
  1. Smith AM, Dowd AJ, McGonigle S, Keegan PS, Brennan G, Trudgett A, Dalton JP: Purification of a cathepsin L-like proteinase secreted by adult Fasciola hepatica. Mol Biochem Parasitol. 1993 Nov;62(1):1-8. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB12245Triclabendazoleapproved, investigationalunknowninhibitorDetails