CYP2B protein
Details
- Name
- CYP2B protein
- Synonyms
- CYP2B7
- Cytochrome P450 2B7 short isoform
- Gene Name
- CYP2B
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0010738|CYP2B protein MELSVLLFLALLTGLLLLLVQRHPNSHGTLPPGPRPLPLLGNLLQMDRRGLLKSFLRFRE KYGDVFTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNR WKVLRRFSVTTMRDFGMGKRSVEERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIIC SIIFGKRFHYQDQEFLKTLNLFCQSFLLISSISSQLFELFSGFLKYFPGAHRQVYKNLQE INAYIGHSVEKHRETLDPSAPRDLIDTYLLHMEKEKSNPHSEFSHQNLIINTLSLFFAGT ETTSTTLRYGFLLMLKYPHVAERVYKEIEQVVGPHRPPALDDRAKMPYTEAVIREIQRFA DLLPMGVPHIVTQHTSF
- Number of residues
- 377
- Molecular Weight
- 43147.81
- Theoretical pI
- 9.03
- GO Classification
- Functionsheme binding / iron ion binding / oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- General Function
- Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- Specific Function
- Not Available
- Pfam Domain Function
- p450 (PF00067)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0002094|1134 bp ATGGAGCTCAGCGTCCTCCTCTTCCTTGCACTCCTCACAGGCCTCTTGCTACTCCTGGTT CAGCGTCACCCTAACTCCCATGGCACCCTCCCACCAGGGCCCCGCCCTCTGCCCCTTTTG GGGAACCTTCTGCAGATGGACAGAAGAGGCCTACTCAAATCCTTTCTGAGGTTCCGAGAG AAATATGGGGACGTCTTCACGGTACACCTGGGACCGAGGCCCGTGGTCATGCTGTGTGGA GTAGAGGCCATACGGGAGGCCCTGGTGGACAACGCTGAGGCCTTCTCTGGCCGGGGAAAA ATCGTCATCATGGACCCAGTCTACCAGGGATATGGCATGCTCTTTGCCAATGGAAACCGC TGGAAGGTGCTTCGGCGATTCTCTGTGACCACCATGAGGGACTTCGGGATGGGAAAGCGG AGTGTGGAGGAGCGGATTCAGGACGAGGCTCAGTGTCTGATAGAGGAACTTCGGAAATCC AAGGGAGCCCTCGTGGACCCCACCTTCCTCTTCCATTCCATTACCGCCAACATCATCTGC TCCATCATCTTTGGAAAACGCTTCCACTACCAAGATCAAGAGTTCCTGAAGACGCTGAAC TTGTTCTGCCAGAGTTTCTTACTCATCAGCTCTATATCCAGCCAGCTGTTTGAGCTCTTC TCTGGCTTCTTGAAATACTTTCCTGGGGCACACAGGCAAGTTTACAAAAACCTACAGGAA ATCAATGCTTACATTGGCCACAGTGTGGAGAAGCACCGTGAAACCCTGGACCCCAGCGCC CCCAGGGACCTCATCGACACCTACCTGCTCCACATGGAAAAAGAGAAATCCAACCCACAC AGTGAATTCAGCCACCAGAACCTCATCATCAACACGCTCTCGCTCTTCTTTGCTGGCACT GAGACCACCAGCACCACTCTCCGCTACGGCTTCCTGCTCATGCTCAAATACCCTCATGTC GCAGAGAGAGTCTACAAGGAGATTGAACAGGTGGTTGGCCCACATCGCCCTCCAGCGCTT GATGACCGAGCCAAAATGCCATACACAGAGGCAGTCATCCGTGAGATTCAGAGATTTGCT GACCTTCTCCCCATGGGTGTGCCCCACATTGTCACCCAACACACCAGCTTCTGA
- Chromosome Location
- Not Available
- Locus
- 19q13.2
- External Identifiers
Resource Link UniProtKB ID Q14097 UniProtKB Entry Name Q14097_HUMAN GenBank Protein ID 181294 GenBank Gene ID M29873 - General References
- Yamano S, Nhamburo PT, Aoyama T, Meyer UA, Inaba T, Kalow W, Gelboin HV, McBride OW, Gonzalez FJ: cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver. Biochemistry. 1989 Sep 5;28(18):7340-8. [Article]
Drug Relations
- Drug Relations
DrugBank ID Name Drug group Pharmacological action? Actions Details DB01149 Nefazodone approved, withdrawn unknown inhibitor Details DB01104 Sertraline approved unknown inducer Details DB00472 Fluoxetine approved, vet_approved unknown inducer Details DB00366 Doxylamine approved, vet_approved unknown inducer Details DB11431 Moxidectin approved, investigational, vet_approved no substrate Details