Solute carrier family 10 member 6
Details
- Name
- Solute carrier family 10 member 6
- Synonyms
- SOAT
- Sodium-dependent organic anion transporter
- Gene Name
- SLC10A6
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0013274|Solute carrier family 10 member 6 MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWS HIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVD GDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGV YVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVT GFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLID GFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGP MDCHRALEPVGHITSCE
- Number of residues
- 377
- Molecular Weight
- 41258.24
- Theoretical pI
- Not Available
- GO Classification
- Functionsbile acid / sodium-dependent organic anion transmembrane transporter activityProcessesbile acid and bile salt transport / sodium-dependent organic anion transport / transmembrane transportComponentsintegral component of plasma membrane / plasma membrane
- General Function
- Sodium-dependent organic anion transmembrane transporter activity
- Specific Function
- Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner.
- Pfam Domain Function
- SBF (PF01758)
- Transmembrane Regions
- 30-50 68-88 98-118 134-154 160-180 196-216 227-247 267-285 291-311
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0013275|Solute carrier family 10 member 6 (SLC10A6) ATGAGAGCCAATTGTTCCAGCAGCTCAGCCTGCCCTGCCAACAGTTCAGAGGAGGAGCTG CCAGTGGGACTGGAGGTGCATGGAAACCTGGAGCTCGTTTTCACAGTGGTGTCCACTGTG ATGATGGGGCTGCTCATGTTCTCTTTGGGATGTTCCGTGGAGATCCGGAAGCTGTGGTCG CACATCAGGAGACCCTGGGGCATTGCTGTGGGACTGCTCTGCCAGTTTGGGCTCATGCCT TTTACAGCTTATCTCCTGGCCATTAGCTTTTCTCTGAAGCCAGTCCAAGCTATTGCTGTT CTCATCATGGGCTGCTGCCCGGGGGGCACCATCTCTAACATTTTCACCTTCTGGGTTGAT GGAGATATGGATCTCAGCATCAGTATGACAACCTGTTCCACCGTGGCCGCCCTGGGAATG ATGCCACTCTGCATTTATCTCTACACCTGGTCCTGGAGTCTTCAGCAGAATCTCACCATT CCTTATCAGAACATAGGAATTACCCTTGTGTGCCTGACCATTCCTGTGGCCTTTGGTGTC TATGTGAATTACAGATGGCCAAAACAATCCAAAATCATTCTCAAGATTGGGGCCGTTGTT GGTGGGGTCCTCCTTCTGGTGGTCGCAGTTGCTGGTGTGGTCCTGGCGAAAGGATCTTGG AATTCAGACATCACCCTTCTGACCATCAGTTTCATCTTTCCTTTGATTGGCCATGTCACG GGTTTTCTGCTGGCACTTTTTACCCACCAGTCTTGGCAAAGGTGCAGGACAATTTCCTTA GAAACTGGAGCTCAGAATATTCAGATGTGCATCACCATGCTCCAGTTATCTTTCACTGCT GAGCACTTGGTCCAGATGTTGAGTTTCCCACTGGCCTATGGACTCTTCCAGCTGATAGAT GGATTTCTTATTGTTGCAGCATATCAGACGTACAAGAGGAGATTGAAGAACAAACATGGA AAAAAGAACTCAGGTTGCACAGAAGTCTGCCATACGAGGAAATCGACTTCTTCCAGAGAG ACCAATGCCTTCTTGGAGGTGAATGAAGAAGGTGCCATCACTCCTGGGCCACCAGGGCCA ATGGATTGCCACAGGGCTCTCGAGCCAGTTGGCCACATCACTTCATGTGAATAG
- Chromosome Location
- 4
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q3KNW5 UniProtKB Entry Name SOAT_HUMAN HGNC ID HGNC:30603 - General References
- Geyer J, Doring B, Meerkamp K, Ugele B, Bakhiya N, Fernandes CF, Godoy JR, Glatt H, Petzinger E: Cloning and functional characterization of human sodium-dependent organic anion transporter (SLC10A6). J Biol Chem. 2007 Jul 6;282(27):19728-41. Epub 2007 May 9. [Article]
- Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [Article]