AppA protein
Details
- Name
- AppA protein
- Synonyms
- Not Available
- Gene Name
- appA
- Organism
- Rhodobacter sphaeroides
- Amino acid sequence
>lcl|BSEQ0017296|AppA protein MQHDLEADVTMTGSDLVSCCYRSLAAPDLTLRDLLDIVETSQAHNARAQLTGALFYSQGV FFQWLEGRPAAVAEVMTHIQRDRRHSNVEILAEEPIAKRRFAGWHMQLSCSEADMRSLGL AESRQIVTVGRSLVADNTNIFSFDRIAAVRRFLSDVCAARTLAPDTPVEADTFALYALTE AQAGRSGRAKAVARLSDLLSTDPLGRLTEVEELLRAHAPTAADFARLFEACAERLTRALA EDRISRMQVTLAYSALQMALRRIHHLPDPQKSVGAVLVAGVPGHKPILEAALAAEMLRAV GWSTSVVHPESVAALAARLKTSRTSTLVVAPSLLEGTEQEADTLRFVSALRARTDLPGLS ILVGGRLAQLPPSKLKDSGADAGFAHLALLPAALARVACPANADCCSMRACRMPASQCCD KRINPEFLLANVMPSVLTRISSRQDRRRSA
- Number of residues
- 450
- Molecular Weight
- 48747.305
- Theoretical pI
- 8.08
- GO Classification
- Functionsblue light photoreceptor activity / FAD binding
- General Function
- Fad binding
- Specific Function
- Not Available
- Pfam Domain Function
- BLUF (PF04940)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0007674|1353 bp ATGCAACACGACCTCGAGGCGGACGTCACGATGACGGGCTCGGATCTGGTTTCCTGCTGC TACCGCAGCCTGGCGGCCCCGGATCTGACGCTGCGCGACCTCCTCGACATCGTCGAGACC TCGCAGGCGCACAATGCCCGGGCGCAGCTGACCGGCGCGCTCTTCTACAGCCAGGGCGTC TTCTTCCAGTGGCTCGAAGGCCGCCCCGCCGCCGTGGCGGAGGTCATGACCCACATCCAG CGGGACCGGCGCCACAGCAACGTCGAGATCCTCGCAGAGGAACCGATCGCCAAGCGCCGC TTTGCGGGATGGCACATGCAGCTCTCCTGCTCGGAGGCCGACATGCGCAGCCTCGGGCTG GCCGAGAGCCGGCAGATCGTGACCGTGGGCCGCAGCCTGGTGGCCGACAACACCAACATC TTCTCTTTCGATAGGATCGCCGCCGTGCGCCGTTTCCTCTCCGACGTCTGCGCAGCGCGG ACTCTCGCCCCCGATACCCCCGTCGAGGCGGACACCTTCGCCCTTTATGCCCTGACCGAG GCGCAGGCGGGCCGCTCCGGCCGTGCCAAGGCCGTGGCGCGGCTCTCCGATCTGCTGAGC ACCGATCCGCTCGGTCGCCTGACCGAGGTCGAGGAGCTGCTGCGCGCCCATGCGCCGACC GCCGCCGATTTCGCGCGGCTGTTCGAGGCCTGCGCCGAGCGCCTGACGCGCGCGCTGGCC GAGGATCGCATCTCGCGGATGCAGGTGACGCTGGCCTATTCGGCCCTGCAGATGGCGCTG CGCCGGATCCATCACCTGCCCGACCCGCAGAAGAGCGTGGGCGCCGTGCTGGTCGCCGGC GTGCCGGGTCACAAGCCGATCCTCGAGGCGGCCCTCGCGGCCGAGATGCTGCGCGCCGTG GGCTGGTCGACCTCGGTCGTGCATCCCGAGAGCGTCGCGGCCCTGGCCGCGCGGCTGAAG ACCTCGCGCACCTCGACGCTGGTCGTGGCGCCGAGCCTTCTGGAGGGAACCGAGCAGGAG GCCGACACGCTGCGGTTCGTCTCCGCGCTCAGGGCGCGGACCGATCTTCCCGGCCTGAGC ATCCTGGTCGGGGGCCGGCTGGCGCAACTTCCCCCCTCGAAGCTGAAGGACTCCGGCGCC GATGCCGGGTTCGCACATCTTGCGCTGCTTCCGGCCGCCCTCGCCCGTGTGGCCTGCCCG GCCAATGCCGACTGCTGCTCGATGCGCGCCTGCCGGATGCCCGCGTCCCAATGCTGCGAC AAGCGCATCAACCCCGAATTCCTGCTGGCGAACGTCATGCCGAGCGTGCTGACCCGCATC TCCTCGCGCCAGGACCGCCGCCGCAGCGCCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q53119 UniProtKB Entry Name Q53119_RHOSH GenBank Protein ID 940301 GenBank Gene ID L42555 - General References
- Anderson S, Dragnea V, Masuda S, Ybe J, Moffat K, Bauer C: Structure of a novel photoreceptor, the BLUF domain of AppA from Rhodobacter sphaeroides. Biochemistry. 2005 Jun 7;44(22):7998-8005. [Article]
- Grinstead JS, Hsu ST, Laan W, Bonvin AM, Hellingwerf KJ, Boelens R, Kaptein R: The solution structure of the AppA BLUF domain: insight into the mechanism of light-induced signaling. Chembiochem. 2006 Jan;7(1):187-93. [Article]
- Yin L, Dragnea V, Feldman G, Hammad LA, Karty JA, Dann CE 3rd, Bauer CE: Redox and light control the heme-sensing activity of AppA. MBio. 2013 Aug 27;4(5):e00563-13. doi: 10.1128/mBio.00563-13. [Article]
- Winkler A, Heintz U, Lindner R, Reinstein J, Shoeman RL, Schlichting I: A ternary AppA-PpsR-DNA complex mediates light regulation of photosynthesis-related gene expression. Nat Struct Mol Biol. 2013 Jul;20(7):859-67. doi: 10.1038/nsmb.2597. Epub 2013 Jun 2. [Article]