Glucanase
Details
- Name
- Glucanase
- Synonyms
- 3.2.1.-
- Gene Name
- cbhA
- Organism
- Clostridium thermocellum
- Amino acid sequence
>lcl|BSEQ0011984|Glucanase MKFRRSICTAVLLAVLLTLLVPTSVFALEDNSSTLPPYKNDLLYERTFDEGLCYPWHTCE DSGGKCSFDVVDVPGQPGNKAFAVTVLDKGQNRWRVQMRHRGLTLEQGHTYRVRLKIWAD ASCKVYIKIGQMAEPYAEYWNNKWSPYTLTAGKVLEIDETFVMDKPTDDTCEFTFHLGGE LAATPPYTVYLDDVSLYDPEYTKPVEYILPQPDVRVNQVGYLPEGKKVATVVCNSTQPVK WQLKNAAGVVVLEGYTEPKGLDKDSQDYVHWLDFSDFATEGIGYYFELPTVNSPTNYSHP FDIRKDIYTQMKYDALAFFYHKRSGIPIEMPYAGGEQWTRPAGHIGIEPNKGDTNVPTWP QDDEYAGIPQKNYTKDVTGGWYDAGDHGKYVVNGGIAVWTLMNMYERAKIRGLDNWGPYR DGGMNIPEQNNGYPDILDEARWEIEFFKKMQVTEKEDPSIAGMVHHKIHDFRWTALGMLP HEDPQPRYLRPVSTAATLNFAATLAQSARLWKDYDPTFAADCLEKAEIAWQAALKHPDIY AEYTPGSGGPGGGPYNDDYVGDEFYWAACELYVTTGKDEYKNYLMNSPHYLEMPAKMGEN GGANGEDNGLWGCFTWGTTQGLGTITLALVENGLPATDIQKARNNIAKAADRWLENIEEQ GYRLPIKRAEDERAGYPWGSNSLHFEPDDLVMGYAYDFTGDSNISMECLTGISYLLGRNA MDQSYVTGYGERPLQNPHDRFWTPQTSKRFPAPPPGIISGRPNSRFEDPTINAAVKKDTP PQKCFIDHTDSWSTNEITVNWNAPFAWVTAYLDEQYTDSETDKVTIDSPVAGERFEAGKD INIRTVKSKTPVSKVEFYNGDTLISSDTTAPYTAKITGAAVGAYNLKAVAVLSDGRRIES PVTPVLVKVIVKPTVKLTAPKSNVVAYGNEFLKITATASDSDGKISRVDFLVDGEVIGSD REAPYEYEWKAVEGNHEISVIAYDDDDAASTPDSVKIFVKQARDVKVQYLCENTQTSTQE IKGKFNIVNTGNRDYSLKDIVLRYYFTKEHNSQLQFICYYTPIGSGNLIPSFGGSGDEHY LQLEFKDVKLPAGGQTGEIQFVIRYADNSFHDQSNDYSFDPTIKAFQDYGKVTLYKNGEL VWGTPPGGTEPEEPEEPEEPEEPAIVYGDCNDDGKVNSTDVAVMKRYLKKENVNINLDNA DVNADGKVNSTDFSILKRYVMKNIEELPYR
- Number of residues
- 1230
- Molecular Weight
- 138077.365
- Theoretical pI
- 4.62
- GO Classification
- Functionscellulase activity / cellulose binding / metal ion bindingProcessespolysaccharide catabolic process
- General Function
- Metal ion binding
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0005518|3693 bp ATGAAATTTAGAAGGTCAATTTGTACTGCTGTTTTGTTGGCGGTTTTATTGACACTTCTG GTACCGACATCCGTGTTTGCCTTAGAAGATAATTCTTCGACTTTGCCGCCGTATAAAAAC GACCTTTTGTATGAGAGGACTTTTGATGAGGGACTTTGTTATCCATGGCATACCTGTGAA GACAGCGGAGGAAAATGCTCCTTTGATGTGGTCGATGTTCCGGGGCAGCCCGGTAATAAA GCATTTGCCGTTACTGTTCTTGACAAAGGGCAAAACAGATGGAGAGTTCAGATGAGACAC CGTGGTCTTACTCTTGAACAGGGACATACATATAGAGTACGGCTTAAGATTTGGGCAGAT GCGTCCTGTAAAGTTTATATAAAAATAGGACAAATGGCGGAGCCCTATGCTGAATATTGG AACAACAAGTGGAGTCCATACACACTGACAGCAGGTAAGGTATTGGAAATTGACGAGACG TTTGTTATGGACAAGCCAACTGACGACACATGCGAATTTACATTCCATTTAGGTGGCGAA TTGGCAGCAACTCCTCCATATACAGTTTATCTTGATGATGTATCCCTTTATGACCCAGAA TATACGAAGCCTGTTGAATATATACTTCCGCAGCCTGATGTACGTGTGAACCAGGTTGGC TACCTGCCGGAGGGCAAGAAAGTTGCCACTGTGGTATGCAATTCAACTCAGCCGGTAAAA TGGCAGCTTAAGAATGCTGCAGGCGTTGTAGTTTTGGAAGGTTATACCGAACCAAAGGGT CTTGACAAAGACTCGCAGGATTATGTACATTGGCTTGATTTTTCCGATTTTGCAACCGAA GGAATTGGTTACTATTTTGAACTTCCGACTGTAAACAGTCCTACAAACTACAGTCATCCA TTTGACATTCGCAAAGACATCTATACTCAGATGAAATATGATGCATTGGCATTCTTCTAT CACAAGAGAAGCGGTATTCCTATTGAAATGCCGTATGCAGGAGGAGAACAGTGGACCAGA CCTGCAGGACATATCGGAATTGAGCCGAACAAGGGAGATACAAATGTTCCTACATGGCCT CAGGATGATGAGTATGCAGGAATACCTCAGAAGAATTATACAAAGGATGTAACCGGTGGA TGGTATGATGCCGGTGACCACGGTAAATATGTTGTAAACGGCGGTATAGCCGTCTGGACA TTAATGAACATGTATGAGAGGGCAAAAATTAGAGGTCTTGACAACTGGGGACCATACAGG GACGGCGGAATGAACATACCGGAGCAGAATAACGGTTATCCGGACATTCTTGATGAAGCA AGATGGGAAATTGAGTTCTTTAAGAAAATGCAGGTAACTGAAAAAGAGGATCCTTCCATA GCCGGAATGGTACACCACAAAATTCACGACTTCAGATGGACTGCTTTGGGTATGTTGCCT CACGAAGATCCCCAGCCACGTTACTTAAGGCCGGTAAGTACGGCTGCGACTTTGAACTTT GCGGCAACTTTGGCACAAAGTGCACGTCTTTGGAAAGATTATGATCCGACTTTTGCTGCT GACTGTTTGGAAAAGGCTGAAATAGCATGGCAGGCGGCATTAAAGCATCCTGATATTTAT GCTGAGTATACTCCCGGTAGCGGTGGTCCCGGAGGCGGACCATACAATGACGACTATGTC GGAGACGAATTCTACTGGGCAGCCTGCGAACTTTATGTAACAACAGGAAAAGACGAATAT AAGAATTACCTGATGAATTCACCTCACTATCTTGAAATGCCTGCAAAGATGGGTGAAAAC GGTGGAGCAAACGGAGAAGACAACGGATTGTGGGGATGCTTCACCTGGGGAACTACTCAA GGATTGGGAACCATTACTCTTGCTTTGGTTGAAAACGGATTGCCTGCTACAGACATTCAA AAGGCAAGAAACAATATAGCTAAAGCTGCTGACAGATGGCTTGAGAATATTGAAGAGCAA GGTTACAGACTGCCGATCAAACGGGCGGAGGATGAGAGAGCCGGTTATCCATGGGGTTCA AACTCCTTGCATTTTGAACCAGATGACCTAGTTATGGGATATGCCTATGACTTTACAGGT GACTCAAATATCTCGATGGAATGTTTGACCGGCATAAGCTACCTGTTGGGAAGAAACGCA ATGGATCAGTCCTATGTAACAGGGTATGGTGAGCGTCCGCTTCAGAATCCTCATGACAGG TTCTGGACGCCGCAGACAAGTAAGAGATTCCCTGCTCCACCTCCGGGTATAATTTCCGGC CGTCCGAACTCCCGTTTCGAGGACCCGACAATAAATGCGGCCGTTAAGAAGGATACACCG CCACAGAAATGTTTTATCGACCATACAGACTCATGGTCAACCAACGAGATAACTGTTAAC TGGAATGCTCCGTTTGCATGGGTTACAGCTTATCTTGACGAGCAGTACACAGACAGTGAA ACCGATAAGGTAACTATTGATTCGCCTGTTGCAGGAGAAAGATTTGAAGCGGGTAAAGAC ATTAATATAAGAACTGTTAAATCAAAAACTCCTGTAAGCAAAGTAGAGTTTTACAATGGA GATACGCTTATTTCCAGTGACACAACTGCACCTTACACAGCAAAGATAACAGGAGCCGCT GTCGGAGCATATAACCTTAAAGCGGTTGCAGTGCTGTCTGACGGAAGAAGAATTGAGTCA CCGGTAACTCCTGTACTTGTTAAGGTAATTGTGAAACCTACTGTAAAACTTACTGCACCC AAGTCAAATGTTGTGGCTTATGGAAATGAGTTCCTGAAGATTACAGCAACAGCCAGTGAC TCTGACGGCAAAATCTCCAGGGTTGATTTCCTTGTTGACGGTGAAGTAATCGGTTCAGAC AGGGAAGCACCTTATGAATATGAGTGGAAAGCTGTGGAAGGCAATCACGAAATAAGTGTA ATTGCTTATGATGATGACGATGCGGCTTCAACACCTGATTCCGTAAAAATATTTGTAAAA CAGGCACGGGATGTAAAAGTACAGTATTTGTGCGAAAATACGCAAACATCCACTCAGGAA ATCAAGGGTAAATTCAATATAGTTAACACAGGAAACAGAGATTATTCGCTGAAAGATATA GTATTAAGATACTACTTTACCAAGGAGCACAATTCACAGCTTCAGTTTATCTGCTATTAT ACACCCATAGGCTCCGGAAATCTCATTCCGTCCTTTGGCGGCTCGGGTGACGAGCATTAT CTGCAGCTGGAATTCAAAGATGTCAAGCTGCCTGCCGGCGGTCAGACTGGGGAAATACAG TTTGTTATAAGATATGCAGATAACTCCTTCCATGATCAGTCGAACGACTATTCGTTCGAT CCAACTATAAAAGCGTTCCAGGATTATGGCAAGGTTACCCTGTATAAGAATGGAGAACTT GTTTGGGGAACGCCGCCGGGCGGTACAGAACCTGAAGAACCGGAAGAGCCTGAAGAACCG GAAGAGCCTGCGATAGTTTACGGCGACTGTAATGATGACGGCAAAGTAAATTCAACAGAC GTCGCAGTAATGAAGAGATATTTAAAGAAAGAAAATGTTAATATTAATCTTGACAATGCA GATGTGAATGCGGACGGCAAAGTTAACTCAACAGACTTCTCAATACTTAAGAGATATGTT ATGAAGAACATAGAAGAATTGCCATATCGATAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q59325 UniProtKB Entry Name Q59325_CLOTM GenBank Gene ID X80993 - General References
- Schubot FD, Kataeva IA, Chang J, Shah AK, Ljungdahl LG, Rose JP, Wang BC: Structural basis for the exocellulase activity of the cellobiohydrolase CbhA from Clostridium thermocellum. Biochemistry. 2004 Feb 10;43(5):1163-70. [Article]
- Yaniv O, Petkun S, Shimon LJ, Bayer EA, Lamed R, Frolow F: A single mutation reforms the binding activity of an adhesion-deficient family 3 carbohydrate-binding module. Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):819-28. doi: 10.1107/S0907444912013133. Epub 2012 Jun 15. [Article]