DNA-directed RNA polymerase subunit alpha
Details
- Name
- DNA-directed RNA polymerase subunit alpha
- Synonyms
- 2.7.7.6
- RNA polymerase subunit alpha
- RNAP subunit alpha
- Transcriptase subunit alpha
- Gene Name
- rpoA
- Organism
- Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
- Amino acid sequence
>lcl|BSEQ0019548|DNA-directed RNA polymerase subunit alpha MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIED VLHEFSTIPGVKEDVVEIILNLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADV EIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDRINAIPVDAVFSPVRRVAFQ VEDTRLGQRTDLDKLTLRIWTDGSVTPLEALNQAVEILREHLTYFSNPQAAAVAAPEEAK EPEAPPEQEEELDLPLEELGLSTRVLHSLKEEGIESVRALLALNLKDLKNIPGIGERSLE EIKEALEKKGFTLKE
- Number of residues
- 315
- Molecular Weight
- 35012.91
- Theoretical pI
- 4.64
- GO Classification
- FunctionsDNA binding / DNA-directed RNA polymerase activityProcessesDNA repair / transcription, DNA-templated
- General Function
- Dna-directed rna polymerase activity
- Specific Function
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasmic
- Gene sequence
>lcl|BSEQ0019549|DNA-directed RNA polymerase subunit alpha (rpoA) ATGTTGGATTCCAAGCTCAAGGCCCCGGTCTTCACGGTGCGCACCCAGGGGCGGGAGTAC GGGGAGTTCGTCCTGGAGCCCCTGGAGCGGGGCTTCGGCGTCACCCTGGGAAACCCCCTG CGGCGCATCCTCCTTTCCTCCATCCCTGGGACCGCGGTCACCAGCGTCTACATTGAGGAC GTCCTCCACGAGTTCTCCACCATCCCCGGGGTCAAGGAGGACGTGGTGGAGATCATCCTC AACCTCAAGGAGCTGGTGGTCCGGTTCCTGAACCCCAGCCTCCAGACCGTGACCCTCCTC CTCAAGGCCGAGGGCCCCAAGGAGGTGAAGGCGCGGGACTTCCTTCCCGTGGCCGACGTG GAGATCATGAACCCCGACCTCCACATCGCCACCCTGGAGGAGGGGGGTCGGCTCAACATG GAGGTCCGGGTGGACCGGGGGGTGGGGTACGTCCCGGCGGAGAAGCACGGCATCAAGGAC CGGATCAACGCCATCCCGGTGGACGCCGTCTTCTCCCCGGTGCGCCGCGTGGCCTTCCAG GTGGAGGACACCCGCCTGGGGCAGCGCACCGACCTGGACAAGCTCACCCTCAGGATCTGG ACCGACGGCTCCGTCACCCCCCTCGAGGCCCTGAACCAGGCGGTGGAGATCCTCCGGGAG CACCTCACCTACTTCTCCAACCCCCAGGCGGCCGCCGTGGCGGCCCCCGAGGAGGCCAAG GAGCCCGAGGCGCCGCCAGAGCAGGAGGAGGAGCTGGACCTGCCCTTGGAGGAGCTCGGC CTCTCCACCCGGGTGCTCCACAGCCTCAAGGAGGAGGGCATTGAGTCCGTCCGGGCCCTT CTCGCCCTCAACCTCAAGGACCTGAAGAACATCCCCGGGATTGGGGAGCGGAGCCTGGAG GAGATCAAGGAAGCCCTGGAGAAGAAGGGCTTCACCCTGAAGGAGTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q5SHR6 UniProtKB Entry Name RPOA_THET8 GenBank Protein ID 4519419 GenBank Gene ID AB024328 - General References
- Wada T, Yamazaki T, Kuramitsu S, Kyogoku Y: Cloning of the RNA polymerase alpha subunit gene from Thermus thermophilus HB8 and characterization of the protein. J Biochem. 1999 Jan;125(1):143-50. [Article]