Solute carrier family 22 member 10
Details
- Name
- Solute carrier family 22 member 10
- Synonyms
- OAT5
- Organic anion transporter 5
- Gene Name
- SLC22A10
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0037252|Solute carrier family 22 member 10 MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGS GNETGILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGW VYDQSYFPSTIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCL LQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISNNSLPITEWIRPNSKALVVILSSGA LSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALR KVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKTTVCDLFRNPSMRKRICILVFLRFAN TIPFYGTMVNLQHVGSNIFLLQVLYGAVALIVRCLALLTLNHMGRRISQILFMFLVGLSI LANTFVPKEMQTLRVALACLGIGCSAATFSSVAVHFIELIPTVLRARASGIDLTASRIGA ALAPLLMTLTVFFTTLPWIIYGIFPIIGGLIVFLLPETKNLPLPDTIKDVENQKKNLKEK A
- Number of residues
- 541
- Molecular Weight
- 60256.57
- Theoretical pI
- 8.31
- GO Classification
- Functionsinorganic anion exchanger activity / sodium-independent organic anion transmembrane transporter activityProcessesanion transmembrane transport / sodium-independent organic anion transportComponentsintegral component of plasma membrane
- General Function
- Sodium-independent organic anion transmembrane transporter activity
- Specific Function
- Not Available
- Pfam Domain Function
- Sugar_tr (PF00083)
- Transmembrane Regions
- 16-36 146-166 194-214 231-251 260-280 350-370 378-398 407-427 437-457 473-493 496-516
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0017171|Solute carrier family 22 member 10 (SLC22A10) ATGGCCTTTGAGGAGCTCTTGAGTCAAGTTGGAGGCCTTGGGAGATTTCAGATGCTTCAT CTGGTTTTTATTCTTCCCTCTCTCATGTTATTAATCCCTCATATACTGCTAGAGAACTTT GCTGCAGCCATTCCTGGTCATCGTTGCTGGGTCCACATGCTGGACAATAATACTGGATCT GGTAATGAAACTGGAATCCTCAGTGAAGATGCCCTCTTGAGAATCTCTATCCCACTAGAC TCAAATCTGAGGCCAGAGAAGTGTCGTCGCTTTGTCCATCCCCAGTGGCAGCTTCTTCAC CTGAATGGGACTATCCACAGCACAAGTGAGGCAGACACAGAACCCTGTGTGGATGGCTGG GTATATGATCAAAGCTACTTCCCTTCGACCATTGTGACTAAGTGGGACCTGGTATGTGAT TATCAGTCACTGAAATCAGTGGTTCAATTCCTACTTCTGACTGGAATGCTGGTGGGAGGC ATCATAGGTGGCCATGTCTCAGACAGGTTTGGGCGAAGATTTATTCTCAGATGGTGTTTG CTCCAGCTTGCCATTACTGACACCTGCGCTGCCTTCGCTCCCACCTTCCCTGTTTACTGT GTACTACGCTTCTTGGCAGGTTTTTCTTCCATGATCATTATATCAAATAATTCTTTGCCC ATTACTGAGTGGATAAGGCCCAACTCTAAAGCCCTGGTAGTAATATTGTCATCTGGTGCC CTTAGTATTGGACAGATAATCCTGGGAGGCTTGGCTTATGTCTTCCGAGACTGGCAAACC CTGCACGTGGTGGCGTCTGTACCTTTCTTTGTCTTCTTTCTTCTTTCAAGGTGGCTGGTG GAATCTGCTCGGTGGTTGATAATCACCAATAAACTAGATGAGGGCTTAAAGGCACTTAGA AAAGTTGCACGCACAAATGGAATAAAGAATGCTGAAGAAACCCTGAACATAGAGGTTGTA AGATCCACCATGCAGGAGGAGCTGGATGCAGCACAGACCAAAACTACTGTGTGTGACTTG TTCCGCAACCCCAGTATGCGTAAAAGGATCTGTATCCTGGTATTTTTGAGATTTGCAAAC ACAATACCTTTTTATGGTACCATGGTCAATCTTCAGCATGTGGGGAGCAACATTTTCCTG TTGCAGGTACTTTATGGAGCTGTCGCTCTCATAGTTCGATGTCTTGCTCTTTTGACACTA AATCATATGGGCCGTCGAATAAGCCAGATATTGTTCATGTTCCTGGTGGGCCTTTCCATT TTGGCCAACACGTTTGTGCCCAAAGAAATGCAGACCCTGCGTGTGGCTTTGGCATGTCTG GGAATCGGCTGTTCTGCTGCTACTTTTTCCAGTGTTGCTGTTCACTTCATTGAACTCATC CCCACTGTTCTCAGGGCAAGAGCTTCAGGAATAGATTTAACGGCTAGTAGGATTGGAGCA GCACTGGCTCCCCTCTTGATGACCTTAACGGTATTTTTTACCACTTTGCCATGGATCATT TATGGAATCTTCCCCATCATTGGTGGCCTTATTGTCTTCCTCCTACCAGAAACCAAGAAT CTGCCTTTGCCTGACACCATCAAGGATGTGGAAAATCAAAAAAAAAATCTCAAGGAAAAG GCATAA
- Chromosome Location
- 11
- Locus
- 11q12.3
- External Identifiers
Resource Link UniProtKB ID Q63ZE4 UniProtKB Entry Name S22AA_HUMAN GenBank Protein ID 52078132 GenBank Gene ID BK001421 HGNC ID HGNC:18057 - General References
- Yamada S, Ohira M, Horie H, Ando K, Takayasu H, Suzuki Y, Sugano S, Hirata T, Goto T, Matsunaga T, Hiyama E, Hayashi Y, Ando H, Suita S, Kaneko M, Sasaki F, Hashizume K, Ohnuma N, Nakagawara A: Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. Oncogene. 2004 Aug 5;23(35):5901-11. [Article]
- Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA, Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C, Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y: Human chromosome 11 DNA sequence and analysis including novel gene identification. Nature. 2006 Mar 23;440(7083):497-500. [Article]
- Sun W, Wu RR, van Poelje PD, Erion MD: Isolation of a family of organic anion transporters from human liver and kidney. Biochem Biophys Res Commun. 2001 May 4;283(2):417-22. [Article]
- Eraly SA, Nigam SK: Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters. Biochem Biophys Res Commun. 2002 Oct 11;297(5):1159-66. [Article]