Zinc transporter 9
Details
- Name
- Zinc transporter 9
- Synonyms
- C4orf1
- HUEL
- Human embryonic lung protein
- Solute carrier family 30 member 9
- ZnT-9
- Gene Name
- SLC30A9
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052343|Zinc transporter 9 MLPGLAAAAAHRCSWSSLCRLRLRCRAAACNPSDRQEWQNLVTFGSFSNMVPCSHPYIGT LSQVKLYSTNVQKEGQGSQTLRVEKVPSFETAEGIGTELKAPLKQEPLQVRVKAVLKKRE YGSKYTQNNFITGVRAINEFCLKSSDLEQLRKIRRRSPHEDTESFTVYLRSDVEAKSLEV WGSPEALAREKKLRKEAEIEYRERLFRNQKILREYRDFLGNTKPRSRTASVFFKGPGKVV MVAICINGLNCFFKFLAWIYTGSASMFSEAIHSLSDTCNQGLLALGISKSVQTPDPSHPY GFSNMRYISSLISGVGIFMMGAGLSWYHGVMGLLHPQPIESLLWAYCILAGSLVSEGATL LVAVNELRRNARAKGMSFYKYVMESRDPSTNVILLEDTAAVLGVIIAATCMGLTSITGNP LYDSLGSLGVGTLLGMVSAFLIYTNTEALLGRSIQPEQVQRLTELLENDPSVRAIHDVKA TDLGLGKVRFKAEVDFDGRVVTRSYLEKQDFDQMLQEIQEVKTPEELETFMLKHGENIID TLGAEVDRLEKELKKRNPEVRHVDLEIL
- Number of residues
- 568
- Molecular Weight
- 63514.525
- Theoretical pI
- Not Available
- GO Classification
- Functionscation transmembrane transporter activity / chromatin binding / DNA-binding transcription factor activity / DNA-binding transcription factor activity, RNA polymerase II-specific / nuclear receptor binding / nuclear receptor transcription coactivator activityProcessescellular zinc ion homeostasis / nucleotide-excision repair / positive regulation of transcription by RNA polymerase II / zinc ion transportComponentscell / cytoplasmic vesicle / cytoskeleton / endoplasmic reticulum / integral component of membrane / nucleus
- General Function
- Acts as a zinc transporter involved in intracellular zinc homeostasis (PubMed:28334855). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).
- Specific Function
- Cation transmembrane transporter activity
- Pfam Domain Function
- Cation_efflux (PF01545)
- Transmembrane Regions
- 239-259 314-334 342-362 392-412 424-444
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0052344|Zinc transporter 9 (SLC30A9) ATGTTACCCGGCTTGGCCGCCGCCGCGGCCCACAGATGTAGCTGGTCCTCCCTGTGCCGG CTCCGTCTGCGATGCAGGGCGGCGGCCTGTAATCCCAGCGACCGCCAGGAGTGGCAGAAT TTAGTGACATTTGGAAGCTTTTCAAACATGGTTCCCTGTAGTCATCCATATATTGGTACC CTGAGTCAAGTAAAGTTGTACTCCACAAATGTTCAGAAAGAAGGACAGGGATCACAAACA CTCAGAGTGGAAAAAGTACCATCATTTGAAACAGCAGAAGGTATAGGCACAGAACTCAAA GCTCCACTTAAGCAAGAACCTCTCCAAGTAAGAGTTAAAGCAGTCCTTAAGAAAAGGGAG TATGGCTCAAAGTACACTCAGAATAATTTCATCACTGGAGTCAGAGCGATAAATGAGTTC TGCCTCAAATCCAGTGATCTAGAACAACTTCGAAAAATCAGACGACGAAGTCCCCATGAA GATACTGAGTCTTTTACTGTATACTTGAGATCAGATGTGGAAGCAAAATCTTTGGAAGTT TGGGGAAGCCCTGAAGCTCTTGCCAGAGAGAAAAAATTGCGTAAGGAAGCAGAAATAGAA TACAGAGAAAGGCTATTTAGAAACCAAAAAATATTAAGAGAATACAGAGATTTCTTGGGA AATACCAAGCCACGCTCCAGAACAGCATCAGTGTTTTTTAAGGGACCAGGAAAAGTGGTG ATGGTTGCAATTTGCATCAATGGATTAAACTGCTTCTTTAAATTTCTTGCCTGGATTTAT ACCGGTTCAGCAAGTATGTTCTCAGAAGCTATACACTCATTATCTGATACTTGTAATCAG GGTTTACTAGCATTGGGCATCAGTAAGTCTGTTCAAACACCAGATCCTTCTCATCCGTAC GGATTTTCAAATATGCGCTATATTTCTTCGCTAATTAGTGGTGTTGGTATTTTCATGATG GGTGCAGGACTATCTTGGTACCATGGAGTCATGGGATTGCTTCATCCTCAACCAATAGAA TCCCTTCTATGGGCATATTGTATTTTAGCAGGATCATTAGTATCTGAAGGAGCAACACTT CTTGTTGCTGTAAATGAACTTCGTAGGAATGCTCGGGCTAAAGGAATGTCATTTTACAAG TATGTAATGGAAAGTCGTGATCCTAGTACAAATGTGATATTATTGGAGGATACTGCTGCA GTCTTGGGAGTTATAATAGCAGCCACTTGCATGGGCCTTACTTCTATAACAGGCAATCCA CTGTATGACAGCCTAGGTTCTTTGGGTGTGGGCACCTTATTAGGCATGGTCTCAGCATTC CTCATCTACACTAACACAGAAGCACTCTTAGGGCGGTCCATCCAGCCAGAACAAGTACAA CGGCTCACTGAACTCCTGGAGAATGACCCATCAGTAAGGGCAATTCATGATGTTAAAGCC ACAGATCTGGGATTAGGTAAAGTAAGATTTAAGGCAGAAGTAGATTTTGATGGGCGAGTT GTTACAAGATCATATTTGGAAAAACAAGATTTTGACCAAATGTTACAAGAAATTCAAGAA GTGAAAACTCCTGAAGAACTAGAGACCTTTATGCTTAAACATGGAGAAAATATTATTGAT ACTTTAGGAGCTGAAGTAGATAGACTTGAGAAGGAACTGAAAAAACGAAATCCTGAAGTT CGACATGTAGATTTGGAGATACTGTGA
- Chromosome Location
- 4
- Locus
- 4p13
- External Identifiers
Resource Link UniProtKB ID Q6PML9 UniProtKB Entry Name ZNT9_HUMAN HGNC ID HGNC:1329 - General References
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