3-mercaptopyruvate sulfurtransferase
Details
- Name
- 3-mercaptopyruvate sulfurtransferase
- Synonyms
- Mercaptopyruvate sulfurtransferase
- Gene Name
- MST
- Organism
- Leishmania major
- Amino acid sequence
>lcl|BSEQ0016771|3-mercaptopyruvate sulfurtransferase MSAPAAAPKHPGKVFLDPSEVKDHLAEYRIVDCRYSLKIKDHGSIQYAKEHVKSAIRADV DTNLSKLVPTSTARHPLPPCAEFIDWCMANGMAGELPVLCYDDECGAMGGCRLWWMLNSL GADAYVINGGFQACKAAGLEMESGEPSSLPRPATHWPFKTAFQHHYLVDEIPPNAIITDA RSADRFASTVRPYAADKMPGHIEGARNLPYTSHLVTRGDGKVLRSEEEIRHNIMTVVQGA GDAADLSSFVFSCGSGVTACINIALVHHLGLGHPYLYCGSWSEYSGLFRPPIMRSIIDDY GMCMQMQTPSLGDNPKANLDTMTLKVDGAPCERPDAEVQSAATHLHAGEAATVYFKSGRV VTIEVPAVPN
- Number of residues
- 370
- Molecular Weight
- 40154.325
- Theoretical pI
- 6.29
- GO Classification
- Functions3-mercaptopyruvate sulfurtransferase activityProcessescyanide metabolic process / cysteine biosynthetic process via cystathionineComponentscytosol
- General Function
- 3-mercaptopyruvate sulfurtransferase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0016772|3-mercaptopyruvate sulfurtransferase (MST) ATGTCTGCTCCTGCTGCTGCGCCGAAACACCCGGGCAAGGTGTTCCTGGACCCGAGCGAG GTAAAGGACCACCTTGCTGAGTACCGCATCGTGGACTGCCGGTACAGCTTGAAGATAAAG GACCACGGCAGCATCCAGTACGCGAAGGAGCACGTGAAGAGCGCCATCCGCGCCGATGTG GATACGAACCTCTCTAAGTTGGTGCCCACCAGCACCGCCCGGCATCCGCTACCGCCCTGT GCTGAGTTTATCGACTGGTGCATGGCGAACGGGATGGCGGGAGAGCTGCCAGTGCTCTGC TACGATGACGAGTGCGGCGCCATGGGTGGATGCCGCCTGTGGTGGATGCTGAACTCTCTT GGCGCCGACGCGTACGTGATCAACGGCGGCTTTCAGGCCTGCAAGGCTGCGGGGCTGGAG ATGGAGTCCGGCGAGCCCTCGTCGCTGCCAAGACCCGCAACGCACTGGCCCTTCAAGACG GCCTTTCAGCATCACTACCTTGTGGATGAAATCCCGCCCAACGCAATCATCACCGACGCG CGCTCCGCCGACCGCTTCGCCTCGACAGTACGACCTTACGCCGCAGACAAGATGCCAGGC CACATCGAAGGTGCGCGTAACCTCCCCTACACGTCGCACCTCGTGACACGCGGTGACGGC AAGGTGCTGCGCAGTGAGGAAGAGATCCGCCACAACATCATGACCGTCGTGCAAGGCGCG GGTGACGCGGCTGATCTATCGAGCTTCGTCTTCTCCTGCGGCAGCGGCGTCACCGCCTGC ATCAATATCGCCCTGGTGCACCACCTCGGCCTGGGCCATCCGTACCTCTACTGTGGCTCC TGGTCTGAGTACAGCGGCCTCTTCCGCCCCCCCATAATGCGCAGCATCATCGACGACTAC GGCATGTGCATGCAAATGCAGACCCCTAGCCTCGGCGACAACCCGAAGGCAAACCTCGAC ACCATGACGCTGAAGGTCGACGGCGCGCCCTGCGAGAGACCCGATGCGGAGGTGCAGAGC GCCGCAACCCACCTCCACGCTGGCGAGGCCGCTACCGTGTACTTCAAGAGCGGCCGCGTC GTCACGATCGAGGTGCCGGCAGTGCCCAACTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q7K9G0 UniProtKB Entry Name Q7K9G0_LEIMA GenBank Gene ID AJ313201 - General References
- Alphey MS, Williams RA, Mottram JC, Coombs GH, Hunter WN: The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase. A three-domain architecture with a serine protease-like triad at the active site. J Biol Chem. 2003 Nov 28;278(48):48219-27. Epub 2003 Sep 1. [Article]
- Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, Berriman M, Sisk E, Rajandream MA, Adlem E, Aert R, Anupama A, Apostolou Z, Attipoe P, Bason N, Bauser C, Beck A, Beverley SM, Bianchettin G, Borzym K, Bothe G, Bruschi CV, Collins M, Cadag E, Ciarloni L, Clayton C, Coulson RM, Cronin A, Cruz AK, Davies RM, De Gaudenzi J, Dobson DE, Duesterhoeft A, Fazelina G, Fosker N, Frasch AC, Fraser A, Fuchs M, Gabel C, Goble A, Goffeau A, Harris D, Hertz-Fowler C, Hilbert H, Horn D, Huang Y, Klages S, Knights A, Kube M, Larke N, Litvin L, Lord A, Louie T, Marra M, Masuy D, Matthews K, Michaeli S, Mottram JC, Muller-Auer S, Munden H, Nelson S, Norbertczak H, Oliver K, O'neil S, Pentony M, Pohl TM, Price C, Purnelle B, Quail MA, Rabbinowitsch E, Reinhardt R, Rieger M, Rinta J, Robben J, Robertson L, Ruiz JC, Rutter S, Saunders D, Schafer M, Schein J, Schwartz DC, Seeger K, Seyler A, Sharp S, Shin H, Sivam D, Squares R, Squares S, Tosato V, Vogt C, Volckaert G, Wambutt R, Warren T, Wedler H, Woodward J, Zhou S, Zimmermann W, Smith DF, Blackwell JM, Stuart KD, Barrell B, Myler PJ: The genome of the kinetoplastid parasite, Leishmania major. Science. 2005 Jul 15;309(5733):436-42. [Article]
- Rogers MB, Hilley JD, Dickens NJ, Wilkes J, Bates PA, Depledge DP, Harris D, Her Y, Herzyk P, Imamura H, Otto TD, Sanders M, Seeger K, Dujardin JC, Berriman M, Smith DF, Hertz-Fowler C, Mottram JC: Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Genome Res. 2011 Dec;21(12):2129-42. doi: 10.1101/gr.122945.111. Epub 2011 Oct 28. [Article]