4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Details
- Name
- 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
- Synonyms
- 2.7.1.148
- 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
- CMK
- Gene Name
- ispE
- Organism
- Shigella flexneri
- Amino acid sequence
>lcl|BSEQ0011115|4-diphosphocytidyl-2-C-methyl-D-erythritol kinase MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGV EHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNH LWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIP TPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGT GACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
- Number of residues
- 283
- Molecular Weight
- 30953.11
- Theoretical pI
- 4.91
- GO Classification
- Functions4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity / ATP bindingProcessesisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway / terpenoid biosynthetic process
- General Function
- Atp binding
- Specific Function
- Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0011116|4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (ispE) ATGCGGACACAGTGGCCCTCTCCGGCAAAACTTAATCTGTTTTTATACATTACCGGTCAG CGTGCGGATGGTTACCACACGCTGCAAACGCTGTTTCAGTTTCTTGATTACGGCGACACC ATCAGCATTGAGCTTCGTGACGATGGGGATATTCGTCTGTTAACGCCCGTTGAAGGCGTG GAACATGAAGATAACCTGATCGTTCGCGCAGCGCGGTTGTTGATGAAAACTGCGGCAGAC AGCGGGCGTCTTCCGACGGGAAGCGGTGCGAATATCAGCATTGACAAGCGTTTGCCGATG GGCGGCGGTCTCGGCGGTGGTTCATCCAATGCCGCGACGGTCCTGGTGGCATTAAATCAT CTCTGGCAATGCGGGCTAAGCATGGATGAGCTGGCGGAAATGGGGCTGACGCTGGGCGCA GATGTTCCTGTCTTTGTTCGGGGGCATGCCGCGTTTGCCGAAGGCGTTGGTGAAATACTA ACGCCGGTGGATCCGCCAGAGAAGTGGTATCTGGTGGCGCACCCTGGTGTAAGTATTCCG ACTCCGGTGATTTTTAAAGATCCTGAACTCCCGCGCAATACGCCAAAAAGGTCAATAGAA ACGTTGCTAAAATGTGAATTCAGCAATGATTGCGAGGTTATCGCAAGAAAACGTTTTCGC GAGGTTGATGCGGTGCTTTCCTGGCTGTTAGAATACGCCCCGTCACGCCTGACTGGGACA GGGGCCTGTGTCTTTGCTGAATTTGATACAGAGTCTGAAGCCCGCCAGGTGCTAGAGCAA GCCCCGGAATGGCTCAATGGCTTTGTGGCGAAAGGCGTTAATCTTTCCCCATTGCACAGA GCCATGCTTTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q83LD8 UniProtKB Entry Name ISPE_SHIFL GenBank Protein ID 24051512 GenBank Gene ID AE005674 - General References
- Jin Q, Yuan Z, Xu J, Wang Y, Shen Y, Lu W, Wang J, Liu H, Yang J, Yang F, Zhang X, Zhang J, Yang G, Wu H, Qu D, Dong J, Sun L, Xue Y, Zhao A, Gao Y, Zhu J, Kan B, Ding K, Chen S, Cheng H, Yao Z, He B, Chen R, Ma D, Qiang B, Wen Y, Hou Y, Yu J: Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res. 2002 Oct 15;30(20):4432-41. [Article]
- Wei J, Goldberg MB, Burland V, Venkatesan MM, Deng W, Fournier G, Mayhew GF, Plunkett G 3rd, Rose DJ, Darling A, Mau B, Perna NT, Payne SM, Runyen-Janecky LJ, Zhou S, Schwartz DC, Blattner FR: Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect Immun. 2003 May;71(5):2775-86. [Article]