Sodium channel protein

Details

Name

Sodium channel protein

Synonyms

Not Available

Gene Name

Not Available

Organism

Pediculus humanus

Amino acid sequence

>lcl|BSEQ0051625|Sodium channel protein
MSDISDFHSEEEQRLFRPFTRESLAAIEQRIAQENEKFKELEKKRADGEIRYDDEDEDEG
PQPDPTLEQGVPIPVRMQGEFPQELASTPLEDIDSYYHNQRTFVVISKGKDIFRFSATNA
MWILDPFNPIRRVAIYILVHPLFSLFIITTILTNCILMIMPTTPAVESTEVIFTGIYTFE
SAVKVMARGFILQPFTYLRDAWNWLDFIVISLAYVTMGIDLGNLAALRTFRVLRALKTVA
IVPGLKTIVGAVIESVKNLRDVIILTMFSLSVFALMGLQIYMGVLTQKCIRNFPMDGSVG
NLTDENWKQFCENTSNWLFNEAKGEYPLCGNSTGAGQCGSNYTCLQGFGPNPDYGYTSFD
SFGWAFLSSFRLMTQDFWENLYQQVLRSAGPWHMLFFIVIIFLGSFYLVNLILAIVAMSY
DELQKKAEEEEAAEEEAMREAEAAAEAKENRAAARAAAAAGRAEAAAAADRGEFVKSPSN
SSWQSYELFVGQEKGNDDNNKERISIQSEGGDSISEQRSRLNATKFRKVSATSLSLPGSP
FNVRRSSRGSHQFTVRNGTGRGRFVGPPTGDRKPLVLSTYLDAQEHLPYADDSNAVTPMS
EENGAMVVPMFYANLGSRHSSYTSHASRMSYTSHGDLLGSFGGNGKGRTKESQLRDRNRA
LRCSQRGLPITEQPTSKFREIEENEDGNCKEKYRRQSDNPFIEPMHNQPTVDMNDVMVLN
DIIEQAGRQSTVSDHGVATYYFPVDEDEEGPSSRDRALALCMKCIDIFCVWDCCWAWLKF
QEFVALLVFDPFVELFITLCIVVNTLFMALDHHDMDKDMDRALKSGNYFFTATFAIEATL
KLIAMSPKFYFQEGWNIFDFIIVALSLLELGLENVQGLSVLRSFRLLRVFKLAKSWPTLN
LLISIMGRTVGALGNLTFVLCIIIFIFAVMGMQLFGKNYTDNVDRFMDKELPRWNFTDFM
HSFMIVFRVLCGEWIQSMWDCMLVGDYSCIPFFLATVVIGNLVVLNLFLALLLSNFGSSS
LSAPTADNDTNKIAEAFNRISRFNAWVKRSILNFLKMLRAKISNQIGDHTGLPDGRDRDT
DLELGDEILVDGMVFRDKKNSKDQLEVAIGDGMEFTIHGDFKEKLRRSKMALNNKNNVIG
NSYAGLNSDNRFESDYITHNEEDTYSNISYGSHRKRIYKDESHKGSIDTFEEDEKGDMSK
EEDEEMDEEEEGESIPEIDVIIDANMEDVMLQDYPSDCCPDHCYKRFPFLAGDDDAPFWQ
GWSNLRLKTFQLIENKYFETAVITMILLSSLALALEDVHLQQRPVLQDILYYMDRIFTVI
FFIEMLIKWLALGFKEYFTNAWCWLDFVIVMVSLINFVASLCGAGGIQAFKTMRTLRALR
PLRAMSRMQGMRVVVNALVQAIPSIFNVLLVCLIFWLIFAIMGVQLFAGKYFKCLDHNKE
VVNHEIIGDSIACAAENYTWENSRMNFDHVGKAYLCLFQVATFKGWIEIMNDAIDSREVG
AQPIRETNIYMYLYFVFFIIFGSFFTLNLFIGVIIDNFNEQKKKAGGSLEMFMTEDQKKY
YNAMKKMGSKKPLKAIPRPKWKPQAIVFEICMNTKFDMIIMLFIGLNMLTMTLDHYKQTE
TFSKVLDTLNLIFIVIFSSECLMKIFALRYHYFVEPWNLFDFVVVILSILGLVLSDIIEK
YFVSPTLLRVVRVAKVGRVLRLVKGAKGIRTLLFALAMSLPALFNICLLLFLVMFIFAIF
GMSFFMHVKPNSGIDDVYNFQTFGQSMILLFQMSTSAGWDGVLNGIINEEDCDVPDNEMG
FPGNCGNSTIGITFLLSYLVISFLIVINMYIAVILENYSQATEDVQEGLTDDDYDMYYEI
WQNFDPDGTRYIRYDQLSEFLDVLEPPLQIHKPNKYKIVSMDIPICKGDKMFCVDILDAL
TKDFFARKGNPIEETVELGEVQARPDEAGYEPVSSTLWRQREEYCARLIQNAWRKHKQQR
VGTDNEEEKPESGSRTPEAGGPGSKDQSPTDSSNARQTEILVESDGFVTKNGHKVVIHSR
SPSIGSKQADV

Number of residues

2051

Molecular Weight

233296.52

Theoretical pI

Not Available

GO Classification

Functions

calcium ion binding / voltage-gated ion channel activity / voltage-gated sodium channel activity

Processes

regulation of ion transmembrane transport

Components

voltage-gated sodium channel complex

General Function

Mediates the voltage-dependent sodium ion permeability of excitable membranes.

Specific Function

Calcium ion binding

Pfam Domain Function

• Ion_trans (PF00520)
• Na_trans_assoc (PF06512)
• Na_trans_cytopl (PF11933)

Transmembrane Regions

133-160 204-226 238-256 262-285 394-416 784-807 828-851 857-881 912-934 954-971 992-1013 1277-1295 1316-1335 1347-1370 1391-1422 1512-1535 1586-1609 1629-1647 1659-1678 1722-1745 1815-1835

Cellular Location

Cell membrane

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	Q86DI9
UniProtKB Entry Name	Q86DI9_9NEOP

General References

Not Available

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB13746	Bioallethrin	approved, experimental	yes	modulator	Details