Choline transporter-like protein 2
Details
- Name
- Choline transporter-like protein 2
- Synonyms
- CTL2
- Solute carrier family 44 member 2
- Gene Name
- SLC44A2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0037173|Choline transporter-like protein 2 MGDERPHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDP RKVIYPTDSRGEFCGQKGTKNENKPYLFYFNIVKCASPLVLLEFQCPTPQICVEKCPDRY LTYLNARSSRDFEYYKQFCVPGFKNNKGVAEVLQDGDCPAVLIPSKPLARRCFPAIHAYK GVLMVGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVSWYWIIIGLV IAMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLG FQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCS LLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKIFDDSPCPFTAKTCNPETFPSSNESR QCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALR KPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYLDQRLKAAENKFAKCL MTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDF LFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIVGSYLIAHGFFSVY GMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTNKKAAES
- Number of residues
- 706
- Molecular Weight
- 80122.695
- Theoretical pI
- 8.71
- GO Classification
- Functionscholine transmembrane transporter activity / signal transducer activityProcessescholine transport / glycerophospholipid biosynthetic process / phosphatidylcholine biosynthetic process / phospholipid metabolic process / positive regulation of I-kappaB kinase/NF-kappaB signaling / signal transduction / small molecule metabolic process / transmembrane transportComponentsextracellular exosome / integral component of membrane / lysosomal membrane / plasma membrane
- General Function
- Signal transducer activity
- Specific Function
- Isoform 1, but not isoform 3, exhibits some choline transporter activity.
- Pfam Domain Function
- Choline_transpo (PF04515)
- Transmembrane Regions
- 34-54 233-253 257-277 316-336 365-385 458-480 505-525 564-584 600-620 639-659
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0011577|Choline transporter-like protein 2 (SLC44A2) ATGGAGGACGAGCGGAAAAACGGAGCCTACGGAACGCCACAGAAGTATGATCCCACTTTC AAAGGACCCATTTACAATAGGGGCTGCACGGATATCATATGCTGTGTGTTCCTGCTCCTG GCCATTGTGGGCTACGTGGCTGTAGGCATCATAGCCTGGACTCATGGAGACCCTCGAAAG GTGATCTACCCCACTGACAGCCGGGGCGAGTTCTGCGGGCAGAAGGGCACAAAAAACGAG AACAAACCCTATCTGTTTTATTTCAACATTGTGAAATGTGCCAGCCCCCTGGTTCTGCTG GAATTCCAATGTCCCACTCCCCAGATCTGCGTGGAAAAATGCCCCGACCGCTACCTCACG TACCTGAATGCTCGCAGCTCCCGGGACTTTGAGTACTATAAGCAGTTCTGTGTTCCTGGC TTCAAGAACAATAAAGGAGTGGCTGAGGTGCTTCAAGATGGTGACTGCCCTGCTGTCCTC ATCCCCAGCAAACCCTTGGCCCGGAGATGCTTCCCCGCTATCCACGCCTACAAGGGTGTC CTGATGGTGGGCAATGAGACGACCTATGAGGATGGGCATGGCTCCCGGAAAAACATCACA GACCTGGTGGAGGGCGCCAAGAAAGCCAATGGAGTCCTAGAGGCGCGGCAACTCGCCATG CGCATATTTGAAGATTACACCGTCTCTTGGTACTGGATTATCATAGGCCTGGTCATTGCC ATGGCGATGAGCCTCCTGTTCATCATCCTGCTTCGCTTCCTGGCTGGTATTATGGTCTGG GTGATGATCATCATGGTGATTCTGGTGCTGGGCTACGGAATATTTCACTGCTACATGGAG TACTCCCGACTGCGTGGTGAGGCCGGCTCTGATGTCTCTTTGGTGGACCTCGGCTTTCAG ACGGATTTCCGGGTGTACCTGCACTTACGGCAGACCTGGTTGGCCTTTATGATCATTCTG AGTATCCTTGAAGTCATTATCATCTTGCTGCTCATCTTTCTCCGGAAGAGAATTCTCATC GCGATTGCACTCATCAAAGAAGCCAGCAGGGCTGTGGGATACGTCATGTGCTCCTTGCTC TACCCACTGGTCACCTTCTTCTTGCTGTGCCTCTGCATCGCCTACTGGGCCAGCACTGCT GTCTTCCTGTCCACTTCCAACGAAGCGGTCTATAAGATCTTTGATGACAGCCCCTGCCCA TTTACTGCGAAAACCTGCAACCCAGAGACCTTCCCCTCCTCCAATGAGTCCCGCCAATGC CCCAATGCCCGTTGCCAGTTCGCCTTCTACGGTGGTGAGTCGGGCTACCACCGGGCCCTG CTGGGCCTGCAGATCTTCAATGCCTTCATGTTCTTCTGGTTGGCCAACTTCGTGCTGGCG CTGGGCCAGGTCACGCTGGCCGGGGCCTTTGCCTCCTACTACTGGGCCCTGCGCAAGCCG GACGACCTGCCGGCCTTCCCGCTCTTCTCTGCCTTTGGCCGGGCGCTCAGGTACCACACA GGCTCCCTGGCCTTTGGCGCGCTCATCCTGGCCATTGTGCAGATCATCCGTGTGATACTC GAGTACCTGGATCAGCGGCTGAAAGCTGCAGAGAACAAGTTTGCCAAGTGCCTCATGACC TGTCTCAAATGCTGCTTCTGGTGCCTGGAGAAGTTCATCAAATTCCTTAATAGGAATGCC TACATCATGATTGCCATCTACGGCACCAATTTCTGCACCTCGGCCAGGAATGCCTTCTTC CTGCTCATGAGAAACATCATCAGAGTGGCTGTCCTGGATAAAGTTACTGACTTCCTCTTC CTGTTGGGCAAACTTCTGATCGTTGGTAGTGTGGGGATCCTGGCTTTCTTCTTCTTCACC CACCGTATCAGGATCGTGCAGGATACAGCACCACCCCTCAATTATTACTGGGTTCCTATA CTGACGGTGATCGTTGGCTCCTACTTGATTGCACACGGTTTCTTCAGCGTCTATGGCATG TGTGTGGACACGCTGTTCCTCTGCTTCTTGGAGGACCTGGAGAGGAATGACGGCTCGGCC GAGAGGCCTTACTTCATGTCTTCCACCCTCAAGAAACTCTTGAACAAGACCAACAAGAAG GCAGCGGAGTCCTGA
- Chromosome Location
- 19
- Locus
- 19p13.1
- External Identifiers
Resource Link UniProtKB ID Q8IWA5 UniProtKB Entry Name CTL2_HUMAN GenBank Protein ID 6996444 GenBank Gene ID AJ245621 GenAtlas ID SLC44A2 HGNC ID HGNC:17292 - General References
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