Ankyrin repeat and protein kinase domain-containing protein 1
Details
- Name
- Ankyrin repeat and protein kinase domain-containing protein 1
- Synonyms
- 2.7.11.1
- PKK2
- Protein kinase PKK2
- SGK288
- Sugen kinase 288
- X-kinase
- Gene Name
- ANKK1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0051700|Ankyrin repeat and protein kinase domain-containing protein 1 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPE SKALARKVSCKLSLRQPGEVNEDISQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYE NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD ANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL VSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLA AYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGW TPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDV QDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
- Number of residues
- 765
- Molecular Weight
- 84631.68
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / protein serine/threonine kinase activity
- General Function
- Not Available
- Specific Function
- Atp binding
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0051701|Ankyrin repeat and protein kinase domain-containing protein 1 (ANKK1) ATGGCTGCCGACCCCACCGAGCTGCGGCTGGGCAGCCTCCCCGTCTTCACCCGCGACGAC TTCGAGGGCGACTGGCGCCTAGTGGCCAGCGGCGGCTTCAGCCAGGTGTTCCAGGCGCGG CACAGGCGCTGGCGGACGGAGTACGCCATCAAGTGCGCCCCCTGCCTTCCACCCGACGCC GCCAGCTCTGATGTGAATTACCTCATTGAAGAAGCTGCCAAAATGAAGAAGATCAAGTTT CAGCACATCGTGTCTATCTACGGGGTGTGCAAGCAGCCCCTGGGTATTGTGATGGAGTTT ATGGCCAACGGCTCCCTGGAGAAGGTGCTGTCCACCCACAGCCTCTGCTGGAAGCTCAGG TTCCGCATCATCCATGAGACCAGCTTGGCCATGAACTTCCTGCACAGCATTAAGCCGCCT CTGCTCCACCTGGACCTCAAGCCGGGCAACATACTCCTGGACAGCAACATGCATGTCAAA ATTTCAGACTTCGGCCTGTCCAAGTGGATGGAACAGTCCACCCGGATGCAGTACATCGAG AGGTCGGCTCTGCGGGGCATGCTCAGCTACATCCCCCCTGAGATGTTCCTGGAGAGTAAC AAGGCCCCAGGACCTAAATATGATGTGTACAGCTTTGCAATTGTCATCTGGGAGCTACTC ACTCAGAAGAAACCATACTCAGGGTTCAACATGATGATGATTATTATCCGAGTGGCGGCA GGCATGCGGCCCTCCCTACAGCCTGTCTCTGACCAATGGCCAAGCGAGGCCCAGCAGATG GTGGACCTGATGAAACGCTGCTGGGACCAGGACCCCAAGAAGAGGCCATGCTTTCTAGAC ATTACCATCGAGACAGACATACTGCTGTCACTGCTGCAGAGTCGTGTGGCAGTCCCAGAG AGCAAGGCCCTGGCCAGGAAGGTGTCCTGCAAGCTGTCGCTGCGCCAGCCCGGGGAGGTT AATGAGGACATCAGCCAGGAACTGATGGACAGTGACTCAGGAAACTACCTGAAGCGGGCC CTTCAGCTCTCCGACCGTAAGAATTTGGTCCCGAGAGATGAGGAACTGTGTATCTATGAG AACAAGGTCACCCCCCTCCACTTCCTGGTGGCCCAGGGCAGTGTGGAGCAGGTGAGGTTG CTGCTGGCCCACGAGGTAGACGTGGACTGCCAGACGGCCTCTGGATACACGCCCCTCCTG ATCGCCGCCCAGGACCAGCAACCCGACCTCTGTGCCCTGCTTTTGGCACATGGTGCTGAT GCCAACCGAGTGGATGAGGATGGCTGGGCCCCACTGCACTTTGCAGCCCAGAATGGGGAT GACGGCACTGCGCGCCTGCTCCTGGACCACGGGGCCTGTGTGGATGCCCAGGAACGTGAA GGGTGGACCCCTCTTCACCTGGCTGCACAGAATAACTTTGAGAATGTGGCACGGCTTCTG GTCTCCCGTCAGGCTGACCCCAACCTGCATGAGGCTGAGGGCAAGACCCCCCTCCATGTG GCCGCCTACTTTGGCCATGTTAGCCTGGTCAAGCTGCTGACCAGCCAGGGGGCTGAGTTG GATGCTCAGCAGAGAAACCTGAGAACACCACTGCACCTGGCAGTAGAGCGGGGCAAAGTG AGGGCCATCCAACACCTGCTGAAGAGTGGAGCGGTCCCTGATGCCCTTGACCAGAGCGGC TACGGCCCACTGCACACTGCAGCTGCCAGGGGCAAATACCTGATCTGCAAGATGCTGCTC AGGTACGGAGCCAGCCTTGAGCTGCCCACCCACCAGGGCTGGACACCCCTGCATCTAGCA GCCTACAAGGGCCACCTGGAGATCATCCATCTGCTGGCAGAGAGCCACGCAAACATGGGT GCTCTTGGAGCTGTGAACTGGACTCCCCTGCACCTAGCTGCACGCCACGGGGAGGAGGCG GTGGTGTCAGCACTGCTGCAGTGTGGGGCTGACCCCAATGCTGCAGAGCAGTCAGGCTGG ACACCCCTCCACCTGGCGGTCCAGAGGAGCACCTTCCTGAGTGTCATCAACCTCCTAGAA CATCACGCAAATGTCCACGCCCGCAACAAGGTGGGCTGGACACCCGCCCACCTGGCCGCC CTCAAGGGCAACACAGCCATCCTCAAAGTGCTGGTCGAGGCAGGCGCCCAGCTGGACGTC CAGGATGGAGTGAGCTGCACACCCCTGCAACTGGCCCTCCGCAGCCGAAAGCAGGGCATC ATGTCCTTCCTAGAGGGCAAGGAGCCGTCAGTGGCCACTCTGGGTGGTTCTAAGCCAGGA GCCGAGATGGAAATTTAG
- Chromosome Location
- 11
- Locus
- 11q23.2
- External Identifiers
Resource Link UniProtKB ID Q8NFD2 UniProtKB Entry Name ANKK1_HUMAN HGNC ID HGNC:21027 - General References
- Neville MJ, Johnstone EC, Walton RT: Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1. Hum Mutat. 2004 Jun;23(6):540-5. [Article]
- Dubertret C, Gouya L, Hanoun N, Deybach JC, Ades J, Hamon M, Gorwood P: The 3' region of the DRD2 gene is involved in genetic susceptibility to schizophrenia. Schizophr Res. 2004 Mar 1;67(1):75-85. [Article]
- Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S: The protein kinase complement of the human genome. Science. 2002 Dec 6;298(5600):1912-34. [Article]
- Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR: Patterns of somatic mutation in human cancer genomes. Nature. 2007 Mar 8;446(7132):153-8. [Article]