Mucin-16
Details
- Name
- Mucin-16
- Synonyms
- CA-125
- CA125
- MUC-16
- Ovarian cancer-related tumor marker CA125
- Ovarian carcinoma antigen CA125
- Gene Name
- MUC16
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0049273|Mucin-16 MLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTSP DKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPAT SMVSGLSSPRTRTSSTEGNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPW DTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDL SPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSI FSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQT AETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNT HHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPT RELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETS PSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTT HQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAA GSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKI STSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAAT SPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSL PSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPT MDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSA APQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTT ILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSM SVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPS PDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTS LTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSE SPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWD PTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPA TKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPG EPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS KSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSA TMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIET GPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGT MGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYA EGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTAL GSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLA TDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAE TTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTI EQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDS TISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSA AKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLT SESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIP VNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSL THELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETST VSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMT ASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVE TSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFL KTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTT PTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASF PTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLK TVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLV FSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLT MNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAP PTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRAR MMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKA SSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPS MARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSET PTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNST WPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMET TVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSPPEAWTNLYSGT PGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHV SLSTSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVD EAYSSTSSWSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGG KTSSASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGIST TITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSN LKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSE RTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTD PNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLETMISPATSQLPFSI GHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIP HTAKTPDATFQRQGQTALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSS SSVLRTLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSS EHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDV SPYMDTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLS NFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSK GPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGL GKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYS PIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASS ATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMT ESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVS WTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTS MEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSE PSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNI ILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTT TQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQD EASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVTSS PQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSP NVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSSTETSTVPYKEL TGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGP HGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSP SSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSST SDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTV GDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTIT EVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESAS HSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMS SPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITH ERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLG DTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQAS RTEISSSRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGIL PWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMT SPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTT YKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTSV STSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVI TSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDT SSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHS SLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEAST NTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGS PETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTF MPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATS AGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTL QEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSIN TAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESET TFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMS PDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHG FSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVH LTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTT TSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLK GTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPS LPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTV MNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLV MTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGS QSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQ NASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASP TMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPG DMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDM LHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSAL ADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSA IETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAE SSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPR PSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDAS AEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSE TTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEAN TVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMT ITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPF VKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGT SSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTT STMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGAT TEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTS TLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPAT TSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILAT SEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVST STPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTS SSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDIS TTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSP VSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTV DTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDF FETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTS MSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFW SGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLP ESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIH PSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMT QPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQST ISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAAT HRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSP LRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAV TQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTL TPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTE VITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMT ALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTS GLVKTTELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSS VLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETS SATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRK ESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVS WPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDA SLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFS EPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTET STVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAEI TITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRF VETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKT SSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITI PSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYG VPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQK SSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSS SSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTS VEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSMA ETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSK TDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTH HLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTI AESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVS TLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEA AHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTALKTTSRATLTTSVYT PTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRTTPSV FNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHS ELDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETR TTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQ VTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSL AAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAE SSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSA IPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTV LPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPG VVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTP LVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSR AVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETS AFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRT TSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPES PHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDV PDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKML TSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPV AITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTH PAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSAT DTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTP VSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPT LTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTS SLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLAT SSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTG TTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGS LFTPLTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTSTFSPGISTS SIPSSTAATVPFMVPFTLNFTITNLQYEEDMRHPGSRKFNATERELQGLLKPLFRNSSLE YLYSGCRLASLRPEKDSSATAVDAICTHRPDPEDLGLDRERLYWELSNLTNGIQELGPYT LDRNSLYVNGFTHRSSMPTTSTPGTSTVDVGTSGTPSSSPSPTTAGPLLMPFTLNFTITN LQYEEDMRRTGSRKFNTMESVLQGLLKPLFKNTSVGPLYSGCRLTLLRPEKDGAATGVDA ICTHRLDPKSPGLNREQLYWELSKLTNDIEELGPYTLDRNSLYVNGFTHQSSVSTTSTPG TSTVDLRTSGTPSSLSSPTIMAAGPLLVPFTLNFTITNLQYGEDMGHPGSRKFNTTERVL QGLLGPIFKNTSVGPLYSGCRLTSLRSEKDGAATGVDAICIHHLDPKSPGLNRERLYWEL SQLTNGIKELGPYTLDRNSLYVNGFTHRTSVPTSSTPGTSTVDLGTSGTPFSLPSPATAG PLLVLFTLNFTITNLKYEEDMHRPGSRKFNTTERVLQTLLGPMFKNTSVGLLYSGCRLTL LRSEKDGAATGVDAICTHRLDPKSPGVDREQLYWELSQLTNGIKELGPYTLDRNSLYVNG FTHWIPVPTSSTPGTSTVDLGSGTPSSLPSPTTAGPLLVPFTLNFTITNLKYEEDMHCPG SRKFNTTERVLQSLLGPMFKNTSVGPLYSGCRLTLLRSEKDGAATGVDAICTHRLDPKSP GVDREQLYWELSQLTNGIKELGPYTLDRNSLYVNGFTHQTSAPNTSTPGTSTVDLGTSGT PSSLPSPTSAGPLLVPFTLNFTITNLQYEEDMHHPGSRKFNTTERVLQGLLGPMFKNTSV GLLYSGCRLTLLRPEKNGAATGMDAICSHRLDPKSPGLNREQLYWELSQLTHGIKELGPY TLDRNSLYVNGFTHRSSVAPTSTPGTSTVDLGTSGTPSSLPSPTTAVPLLVPFTLNFTIT NLQYGEDMRHPGSRKFNTTERVLQGLLGPLFKNSSVGPLYSGCRLISLRSEKDGAATGVD AICTHHLNPQSPGLDREQLYWQLSQMTNGIKELGPYTLDRNSLYVNGFTHRSSGLTTSTP WTSTVDLGTSGTPSPVPSPTTTGPLLVPFTLNFTITNLQYEENMGHPGSRKFNITESVLQ GLLKPLFKSTSVGPLYSGCRLTLLRPEKDGVATRVDAICTHRPDPKIPGLDRQQLYWELS QLTHSITELGPYTLDRDSLYVNGFTQRSSVPTTSTPGTFTVQPETSETPSSLPGPTATGP VLLPFTLNFTITNLQYEEDMRRPGSRKFNTTERVLQGLLMPLFKNTSVSSLYSGCRLTLL RPEKDGAATRVDAVCTHRPDPKSPGLDRERLYWKLSQLTHGITELGPYTLDRHSLYVNGF THQSSMTTTRTPDTSTMHLATSRTPASLSGPMTASPLLVLFTINFTITNLRYEENMHHPG SRKFNTTERVLQGLLRPVFKNTSVGPLYSGCRLTLLRPKKDGAATKVDAICTYRPDPKSP GLDREQLYWELSQLTHSITELGPYTLDRDSLYVNGFTQRSSVPTTSIPGTPTVDLGTSGT PVSKPGPSAASPLLVLFTLNFTITNLRYEENMQHPGSRKFNTTERVLQGLLRSLFKSTSV GPLYSGCRLTLLRPEKDGTATGVDAICTHHPDPKSPRLDREQLYWELSQLTHNITELGPY ALDNDSLFVNGFTHRSSVSTTSTPGTPTVYLGASKTPASIFGPSAASHLLILFTLNFTIT NLRYEENMWPGSRKFNTTERVLQGLLRPLFKNTSVGPLYSGCRLTLLRPEKDGEATGVDA ICTHRPDPTGPGLDREQLYLELSQLTHSITELGPYTLDRDSLYVNGFTHRSSVPTTSTGV VSEEPFTLNFTINNLRYMADMGQPGSLKFNITDNVMQHLLSPLFQRSSLGARYTGCRVIA LRSVKNGAETRVDLLCTYLQPLSGPGLPIKQVFHELSQQTHGITRLGPYSLDKDSLYLNG YNEPGPDEPPTTPKPATTFLPPLSEATTAMGYHLKTLTLNFTISNLQYSPDMGKGSATFN STEGVLQHLLRPLFQKSSMGPFYLGCQLISLRPEKDGAATGVDTTCTYHPDPVGPGLDIQ QLYWELSQLTHGVTQLGFYVLDRDSLFINGYAPQNLSIRGEYQINFHIVNWNLSNPDPTS SEYITLLRDIQDKVTTLYKGSQLHDTFRFCLVTNLTMDSVLVTVKALFSSNLDPSLVEQV FLDKTLNASFHWLGSTYQLVDIHVTEMESSVYQPTSSSSTQHFYLNFTITNLPYSQDKAQ PGTTNYQRNKRNIEDALNQLFRNSSIKSYFSDCQVSTFRSVPNRHHTGVDSLCNFSPLAR RVDRVAIYEEFLRMTRNGTQLQNFTLDRSSVLVDGYSPNRNEPLTGNSDLPFWAVILIGL AGLLGVITCLICGVLVTTRRRKKEGEYNVQQQCPGYYQSHLDLEDLQ
- Number of residues
- 14507
- Molecular Weight
- 1519158.08
- Theoretical pI
- 5.89
- GO Classification
- Processescell adhesion / O-glycan processingComponentsextracellular exosome / extracellular space / extrinsic component of membrane / Golgi lumen / integral component of membrane / plasma membrane / vesicle
- General Function
- Not Available
- Specific Function
- Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
- Pfam Domain Function
- SEA (PF01390)
- Transmembrane Regions
- 14452-14472
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0049274|Mucin-16 (MUC16) ATGCTGAAACCCTCAGGCCTTCCTGGGTCATCTTCTCCCACCCGCTCCTTGATGACAGGG AGCAGGAGCACTAAAGCCACACCAGAAATGGATTCAGGACTGACAGGAGCCACCTTGTCA CCTAAGACATCTACAGGTGCAATCGTGGTGACAGAACATACTCTGCCCTTTACTTCCCCA GATAAGACCTTGGCCAGTCCTACATCTTCGGTTGTGGGAAGAACCACCCAGTCTTTGGGG GTGATGTCCTCTGCTCTCCCTGAGTCAACCTCTAGAGGAATGACACACTCCGAGCAAAGA ACCAGCCCATCGCTGAGTCCCCAGGTCAATGGAACTCCCTCTAGGAACTACCCTGCTACA AGCATGGTTTCAGGATTGAGTTCCCCAAGGACCAGGACCAGTTCCACAGAAGGAAATTTT ACCAAAGAAGCATCTACATACACACTCACTGTAGAGACCACAAGTGGCCCAGTCACTGAG AAGTACACAGTCCCCACTGAGACCTCAACAACTGAAGGTGACAGCACAGAGACCCCCTGG GACACAAGATATATTCCTGTAAAAATCACATCTCCAATGAAAACATTTGCAGATTCAACT GCATCCAAGGAAAATGCCCCAGTGTCTATGACTCCAGCTGAGACCACAGTTACTGACTCA CATACTCCAGGAAGGACAAACCCATCATTTGGGACACTTTATTCTTCCTTCCTTGACCTA TCACCTAAAGGGACCCCAAATTCCAGAGGTGAAACAAGCCTGGAACTGATTCTATCAACC ACTGGATATCCCTTCTCCTCTCCTGAACCTGGCTCTGCAGGACACAGCAGAATAAGTACC AGTGCGCCTTTGTCATCATCTGCTTCAGTTCTCGATAATAAAATATCAGAGACCAGCATA TTCTCAGGCCAGAGTCTCACCTCCCCTCTGTCTCCTGGGGTGCCCGAGGCCAGAGCCAGC ACAATGCCCAACTCAGCTATCCCTTTTTCCATGACACTAAGCAATGCAGAAACAAGTGCC GAAAGGGTCAGAAGCACAATTTCCTCTCTGGGGACTCCATCAATATCCACAAAGCAGACA GCAGAGACTATCCTTACCTTCCATGCCTTCGCTGAGACCATGGATATACCCAGCACCCAC ATAGCCAAGACTTTGGCTTCAGAATGGTTGGGAAGTCCAGGTACCCTTGGTGGCACCAGC ACTTCAGCGCTGACAACCACATCTCCATCTACCACTTTAGTCTCAGAGGAGACCAACACC CATCACTCCACGAGTGGAAAGGAAACAGAAGGAACTTTGAATACATCTATGACTCCACTT GAGACCTCTGCTCCTGGAGAAGAGTCCGAAATGACTGCCACCTTGGTCCCCACTCTAGGT TTTACAACTCTTGACAGCAAGATCAGAAGTCCATCTCAGGTCTCTTCATCCCACCCAACA AGAGAGCTCAGAACCACAGGCAGCACCTCTGGGAGGCAGAGTTCCAGCACAGCTGCCCAC GGGAGCTCTGACATCCTGAGGGCAACCACTTCCAGCACCTCAAAAGCATCATCATGGACC AGTGAAAGCACAGCTCAGCAATTTAGTGAACCCCAGCACACACAGTGGGTGGAGACAAGT CCTAGCATGAAAACAGAGAGACCCCCAGCATCAACCAGTGTGGCAGCCCCTATCACCACT TCTGTTCCCTCAGTGGTCTCTGGCTTCACCACCCTGAAGACCAGCTCCACAAAAGGGATT TGGCTTGAAGAAACATCTGCAGACACACTCATCGGAGAATCCACAGCTGGCCCAACCACC CATCAGTTTGCTGTTCCCACTGGGATTTCAATGACAGGAGGCAGCAGCACCAGGGGAAGC CAGGGCACAACCCACCTACTCACCAGAGCCACAGCATCATCTGAGACATCCGCAGATTTG ACTCTGGCCACGAACGGTGTCCCAGTCTCCGTGTCTCCAGCAGTGAGCAAGACGGCTGCT GGCTCAAGTCCTCCAGGAGGGACAAAGCCATCATATACAATGGTTTCTTCTGTCATCCCT GAGACATCATCTCTACAGTCCTCAGCTTTCAGGGAAGGAACCAGCCTGGGACTGACTCCA TTAAACACTAGACATCCCTTCTCTTCCCCTGAACCAGACTCTGCAGGACACACCAAGATA AGCACCAGCATTCCTCTGTTGTCATCTGCTTCAGTTCTTGAGGATAAAGTGTCAGCGACC AGCACATTCTCACACCACAAAGCCACCTCATCTATTACCACAGGGACTCCTGAAATCTCA ACAAAGACAAAGCCCAGCTCAGCCGTTCTTTCCTCCATGACCCTAAGCAATGCAGCAACA AGTCCTGAAAGAGTCAGAAATGCAACTTCCCCTCTGACTCATCCATCTCCATCAGGGGAA GAGACAGCAGGGAGTGTCCTCACTCTCAGCACCTCTGCTGAGACTACAGACTCACCTAAC ATCCACCCAACTGGGACACTGACTTCAGAATCGTCAGAGAGTCCTAGCACTCTCAGCCTC CCAAGTGTCTCTGGAGTCAAAACCACATTTTCTTCATCTACTCCTTCCACTCATCTATTT ACTAGTGGAGAAGAAACAGAGGAAACTTCGAATCCATCTGTGTCTCAACCTGAGACTTCT GTTTCCAGAGTAAGGACCACCTTGGCCAGCACCTCTGTCCCTACCCCAGTATTCCCCACC ATGGACACCTGGCCTACACGTTCAGCTCAGTTCTCTTCATCCCACCTAGTGAGTGAGCTC AGAGCTACGAGCAGTACCTCAGTTACAAACTCAACTGGTTCAGCTCTTCCTAAAATATCT CACCTCACTGGGACGGCAACAATGTCACAGACCAATAGAGACACGTTTAATGACTCTGCT GCACCCCAAAGCACAACTTGGCCAGAGACTAGTCCCAGATTCAAGACAGGGTTACCTTCA GCAACAACCACTGTTTCAACCTCTGCCACTTCTCTCTCTGCTACTGTAATGGTCTCTAAA TTCACTTCTCCAGCAACTAGTTCCATGGAAGCAACTTCTATCAGGGAACCATCAACAACC ATCCTCACAACAGAGACCACGAATGGCCCAGGCTCTATGGCTGTGGCTTCTACCAACATC CCAATTGGAAAGGGCTACATTACTGAAGGAAGATTGGACACAAGCCATCTGCCCATTGGA ACCACAGCTTCCTCTGAGACATCTATGGATTTTACCATGGCCAAAGAAAGTGTCTCAATG TCAGTATCTCCATCTCAGTCCATGGATGCTGCTGGCTCAAGCACTCCAGGAAGGACAAGC CAATTCGTTGACACATTTTCTGATGATGTCTATCATTTAACATCCAGAGAAATTACAATA CCTAGAGATGGAACAAGCTCAGCTCTGACTCCACAAATGACTGCAACTCACCCTCCATCT CCTGATCCTGGCTCTGCTAGAAGCACCTGGCTTGGCATCTTGTCCTCATCTCCTTCTTCT CCTACTCCCAAAGTCACAATGAGCTCCACATTTTCAACTCAGAGAGTCACCACAAGCATG ATAATGGACACAGTTGAAACTAGTCGGTGGAACATGCCCAACTTACCTTCCACGACTTCC TTGACACCAAGTAATATTCCAACAAGTGGTGCCATAGGAAAAAGCACCCTGGTTCCCTTG GACACTCCATCTCCAGCCACATCATTGGAGGCATCAGAAGGGGGACTTCCAACCCTCAGC ACCTACCCTGAATCAACAAACACACCCAGCATCCACCTCGGAGCACACGCTAGTTCAGAA AGTCCAAGCACCATCAAACTTACCATGGCTTCAGTAGTAAAACCTGGCTCTTACACACCT CTCACCTTCCCCTCAATAGAGACCCACATTCATGTATCAACAGCCAGAATGGCTTACTCT TCTGGGTCTTCACCTGAGATGACAGCTCCTGGAGAGACTAACACTGGTAGTACCTGGGAC CCCACCACCTACATCACCACTACGGATCCTAAGGATACAAGTTCAGCTCAGGTCTCTACA CCCCACTCAGTGAGGACACTCAGAACCACAGAAAACCATCCAAAGACAGAGTCCGCCACC CCAGCTGCTTACTCTGGAAGTCCTAAAATCTCAAGTTCACCCAATCTCACCAGTCCGGCC ACAAAAGCATGGACCATCACAGACACAACTGAACACTCCACTCAATTACATTACACAAAA TTGGCAGAAAAATCATCTGGATTTGAGACACAGTCAGCTCCAGGACCTGTCTCTGTAGTA ATCCCTACCTCCCCTACCATTGGAAGCAGCACATTGGAACTAACTTCTGATGTCCCAGGG GAACCCCTGGTCCTTGCTCCCAGTGAGCAGACCACAATCACTCTCCCCATGGCAACATGG CTGAGTACCAGTTTGACAGAGGAAATGGCTTCAACAGACCTTGATATTTCAAGTCCAAGT TCACCCATGAGTACATTTGCTATTTTTCCACCTATGTCCACACCTTCTCATGAACTTTCA AAGTCAGAGGCAGATACCAGTGCCATTAGAAATACAGATTCAACAACGTTGGATCAGCAC CTAGGAATCAGGAGTTTGGGCAGAACTGGGGACTTAACAACTGTTCCTATCACCCCACTG ACAACCACGTGGACCAGTGTGATTGAACACTCAACACAAGCACAGGACACCCTTTCTGCA ACGATGAGTCCTACTCACGTGACACAGTCACTCAAAGATCAAACATCTATACCAGCCTCA GCATCCCCTTCCCATCTTACTGAAGTCTACCCTGAGCTCGGGACACAAGGGAGAAGCTCC TCTGAGGCAACCACTTTTTGGAAACCATCTACAGACACACTGTCCAGAGAGATTGAGACT GGCCCAACAAACATTCAATCCACTCCACCCATGGACAACACAACAACAGGGAGCAGTAGT AGTGGAGTCACCCTGGGCATAGCCCACCTTCCCATAGGAACATCCTCCCCAGCTGAGACA TCCACAAACATGGCACTGGAAAGAAGAAGTTCTACAGCCACTGTCTCTATGGCTGGGACA ATGGGACTCCTTGTTACTAGTGCTCCAGGAAGAAGCATCAGCCAGTCATTAGGAAGAGTT TCCTCTGTCCTTTCTGAGTCAACTACTGAAGGAGTCACAGATTCTAGTAAGGGAAGCAGC CCAAGGCTGAACACACAGGGAAATACAGCTCTCTCCTCCTCTCTTGAACCCAGCTATGCT GAAGGAAGCCAGATGAGCACAAGCATCCCTCTAACCTCATCTCCTACAACTCCTGATGTG GAATTCATAGGGGGCAGCACATTTTGGACCAAGGAGGTCACCACAGTTATGACCTCAGAC ATCTCCAAGTCTTCAGCAAGGACAGAGTCCAGCTCAGCTACCCTTATGTCCACAGCTTTG GGAAGCACTGAAAATACAGGAAAAGAAAAACTCAGAACTGCCTCTATGGATCTTCCATCT CCAACTCCATCAATGGAGGTGACACCATGGATTTCTCTCACTCTCAGTAATGCCCCCAAT ACCACAGATTCACTTGACCTCAGCCATGGGGTGCACACCAGCTCTGCAGGGACTTTGGCC ACTGACAGGTCATTGAATACTGGTGTCACTAGAGCCTCCAGATTGGAAAACGGCTCTGAT ACCTCTTCTAAGTCCCTGTCTATGGGAAACAGCACTCACACTTCCATGACTTACACAGAG AAGAGTGAAGTGTCTTCTTCAATCCATCCCCGACCTGAGACCTCAGCTCCTGGAGCAGAG ACCACTTTGACTTCCACTCCTGGAAACAGGGCCATAAGCTTAACATTGCCTTTTTCATCC ATTCCAGTGGAAGAAGTCATTTCTACAGGCATAACCTCAGGACCAGACATCAACTCAGCA CCCATGACACATTCTCCCATCACCCCACCAACAATTGTATGGACCAGTACAGGCACAATT GAACAGTCCACTCAACCACTACATGCAGTTTCTTCAGAAAAAGTTTCTGTGCAGACACAG TCAACTCCATATGTCAACTCTGTGGCAGTGTCTGCTTCCCCTACCCATGAGAATTCAGTC TCTTCTGGAAGCAGCACATCCTCTCCATATTCCTCAGCCTCACTTGAATCCTTGGATTCC ACAATCAGTAGGAGGAATGCAATCACTTCCTGGCTATGGGACCTCACTACATCTCTCCCC ACTACAACTTGGCCAAGTACTAGTTTATCTGAGGCACTGTCCTCAGGCCATTCTGGGGTT TCAAACCCAAGTTCAACTACGACTGAATTTCCACTCTTTTCAGCTGCATCCACATCTGCT GCTAAGCAAAGAAATCCAGAAACAGAGACCCATGGTCCCCAGAATACAGCCGCGAGTACT TTGAACACTGATGCATCCTCGGTCACAGGTCTTTCTGAGACTCCTGTGGGGGCAAGTATC AGCTCTGAAGTCCCTCTTCCAATGGCCATAACTTCTAGATCAGATGTTTCTGGCCTTACA TCTGAGAGTACTGCTAACCCGAGTTTAGGCACAGCCTCTTCAGCAGGGACCAAATTAACT AGGACAATATCCCTGCCCACTTCAGAGTCTTTGGTTTCCTTTAGAATGAACAAGGATCCA TGGACAGTGTCAATCCCTTTGGGGTCCCATCCAACTACTAATACAGAAACAAGCATCCCA GTAAACAGCGCAGGTCCACCTGGCTTGTCCACAGTAGCATCAGATGTAATTGACACACCT TCAGATGGGGCTGAGAGTATTCCCACTGTCTCCTTTTCCCCCTCCCCTGATACTGAAGTG ACAACTATCTCACATTTCCCAGAAAAGACAACTCATTCATTTAGAACCATTTCATCTCTC ACTCATGAGTTGACTTCAAGAGTGACACCTATTCCTGGGGATTGGATGAGTTCAGCTATG TCTACAAAGCCCACAGGAGCCAGTCCCTCCATTACACTGGGAGAGAGAAGGACAATCACC TCTGCTGCTCCAACCACTTCCCCCATAGTTCTCACTGCTAGTTTCACAGAGACCAGCACA GTTTCACTGGATAATGAAACTACAGTAAAAACCTCAGATATCCTTGACGCACGGAAAACA AATGAGCTCCCCTCAGATAGCAGTTCTTCTTCTGATCTGATCAACACCTCCATAGCTTCT TCAACTATGGATGTCACTAAAACAGCCTCCATCAGTCCCACTAGCATCTCAGGAATGACA GCAAGTTCCTCCCCATCTCTCTTCTCTTCAGATAGACCCCAGGTTCCCACATCTACAACA GAGACAAATACAGCCACCTCTCCATCTGTTTCCAGTAACACCTATTCTCTTGATGGGGGC TCCAATGTGGGTGGCACTCCATCCACTTTACCACCCTTTACAATCACCCACCCTGTCGAG ACAAGCTCGGCCCTATTAGCCTGGTCTAGACCAGTAAGAACTTTCAGCACCATGGTCAGC ACTGACACTGCCTCCGGAGAAAATCCTACCTCTAGCAATTCTGTGGTGACTTCTGTTCCA GCACCAGGTACATGGACCAGTGTAGGCAGTACTACTGACTTACCTGCCATGGGCTTTCTC AAGACAAGTCCTGCAGGAGAGGCACACTCACTTCTAGCATCAACTATTGAACCAGCCACT GCCTTCACTCCCCATCTCTCAGCAGCAGTGGTCACTGGATCCAGTGCTACATCAGAAGCC AGTCTTCTCACTACGAGTGAAAGCAAAGCCATTCATTCTTCACCACAGACCCCAACTACA CCCACCTCTGGAGCAAACTGGGAAACTTCAGCTACTCCTGAGAGCCTTTTGGTAGTCACT GAGACTTCAGACACAACACTTACCTCAAAGATTTTGGTCACAGATACCATCTTGTTTTCA ACTGTGTCCACGCCACCTTCTAAATTTCCAAGTACGGGGACTCTGTCTGGAGCTTCCTTC CCTACTTTACTCCCGGACACTCCAGCCATCCCTCTCACTGCCACTGAGCCAACAAGTTCA TTAGCTACATCCTTTGATTCCACCCCACTGGTGACTATAGCTTCGGATAGTCTTGGCACA GTCCCAGAGACTACCCTGACCATGTCAGAGACCTCAAATGGTGATGCACTGGTTCTTAAG ACAGTAAGTAACCCAGATAGGAGCATCCCTGGAATCACTATCCAAGGAGTAACAGAAAGT CCACTCCATCCTTCTTCCACTTCCCCCTCTAAGATTGTTGCTCCACGGAATACAACCTAT GAAGGTTCGATCACAGTGGCACTTTCTACTTTGCCTGCGGGAACTACTGGTTCCCTTGTA TTCAGTCAGAGTTCTGAAAACTCAGAGACAACGGCTTTGGTAGACTCATCAGCTGGGCTT GAGAGGGCATCTGTGATGCCACTAACCACAGGAAGCCAGGGTATGGCTAGCTCTGGAGGA ATCAGAAGTGGGTCCACTCACTCAACTGGAACCAAAACATTTTCTTCTCTCCCTCTGACC ATGAACCCAGGTGAGGTTACAGCCATGTCTGAAATCACCACGAACAGACTGACAGCTACT CAATCAACAGCACCCAAAGGGATACCTGTGAAGCCCACCAGTGCTGAGTCAGGCCTCCTA ACACCTGTCTCTGCCTCCTCAAGCCCATCAAAGGCCTTTGCCTCACTGACTACAGCTCCC CCAACTTGGGGGATCCCACAGTCTACCTTGACATTTGAGTTTTCTGAGGTCCCAAGTTTG GATACTAAGTCCGCTTCTTTACCAACTCCTGGACAGTCCCTGAACACCATTCCAGACTCA GATGCAAGCACAGCATCTTCCTCACTGTCCAAGTCTCCAGAAAAAAACCCAAGGGCAAGG ATGATGACTTCCACAAAGGCCATAAGTGCAAGCTCATTTCAATCAACAGGTTTTACTGAA ACCCCTGAGGGATCTGCCTCCCCTTCTATGGCAGGGCATGAACCCAGAGTCCCCACTTCA GGAACAGGGGACCCTAGATATGCCTCAGAGAGCATGTCTTATCCAGACCCAAGCAAGGCA TCATCAGCTATGACATCGACCTCTCTTGCATCAAAACTCACAACTCTCTTCAGCACAGGT CAAGCAGCAAGGTCTGGTTCTAGTTCCTCTCCCATAAGCCTATCCACTGAGAAAGAAACA AGCTTCCTTTCCCCCACTGCATCCACCTCCAGAAAGACTTCACTATTTCTTGGGCCTTCC ATGGCAAGGCAGCCCAACATATTGGTGCATCTTCAGACTTCAGCTCTGACACTTTCTCCA ACATCCACTCTAAATATGTCCCAGGAGGAGCCTCCTGAGTTAACCTCAAGCCAGACCATT GCAGAAGAAGAGGGAACAACAGCTGAAACACAGACGTTAACCTTCACACCATCTGAGACC CCAACATCCTTGTTACCTGTCTCTTCTCCCACAGAACCCACAGCCAGAAGAAAGAGTTCT CCAGAAACATGGGCAAGCTCTATTTCAGTTCCTGCCAAGACCTCCTTGGTTGAAACAACT GATGGAACGCTAGTGACCACCATAAAGATGTCAAGCCAGGCAGCACAAGGAAATTCCACG TGGCCTGCCCCAGCAGAGGAGACGGGGAGCAGTCCAGCAGGCACATCCCCAGGAAGCCCA GAAATGTCTACCACTCTCAAAATCATGAGCTCCAAGGAACCCAGCATCAGCCCAGAGATC AGGTCCACTGTGAGAAATTCTCCTTGGAAGACTCCAGAAACAACTGTTCCCATGGAGACC ACAGTGGAACCAGTCACCCTTCAGTCCACAGCCCTAGGAAGTGGCAGCACCAGCATCTCT CACCTGCCCACAGGAACCACATCACCAACCAAGTCACCAACAGAAAATATGTTGGCTACA GAAAGGGTCTCCCTCTCCCCATCCCCACCTGAGGCTTGGACCAACCTTTATTCTGGAACT CCAGGAGGGACCAGGCAGTCACTGGCCACAATGTCCTCTGTCTCCCTAGAGTCACCAACT GCTAGAAGCATCACAGGGACTGGTCAGCAAAGCAGTCCAGAACTGGTTTCAAAGACAACT GGAATGGAATTCTCTATGTGGCATGGCTCTACTGGAGGGACCACAGGGGACACACATGTC TCTCTGAGCACATCTTCCAATATCCTTGAAGACCCTGTAACCAGCCCAAACTCTGTGAGC TCATTGACAGATAAATCCAAACATAAAACCGAGACATGGGTAAGCACCACAGCCATTCCC TCCACTGTCCTGAATAATAAGATAATGGCAGCTGAACAACAGACAAGTCGATCTGTGGAT GAGGCTTATTCATCAACTAGTTCTTGGTCAGATCAGACATCTGGGAGTGACATCACCCTT GGTGCATCTCCTGATGTCACAAACACATTATACATCACCTCCACAGCACAAACCACCTCA CTAGTGTCTCTGCCCTCTGGAGACCAAGGCATTACAAGCCTCACCAATCCCTCAGGAGGA AAAACAAGCTCTGCGTCATCTGTCACATCTCCTTCAATAGGGCTTGAGACTCTGAGGGCC AATGTAAGTGCAGTGAAAAGTGACATTGCCCCTACTGCTGGGCATCTATCTCAGACTTCA TCTCCTGCGGAAGTGAGCATCCTGGACGTAACCACAGCTCCTACTCCAGGTATCTCCACC ACCATCACCACCATGGGAACCAACTCAATCTCAACTACCACACCCAACCCAGAAGTGGGT ATGAGTACCATGGACAGCACCCCGGCCACAGAGAGGCGCACAACTTCTACAGAACACCCT TCCACCTGGTCTTCCACAGCTGCATCAGATTCCTGGACTGTCACAGACATGACTTCAAAC TTGAAAGTTGCAAGATCTCCTGGAACAATTTCCACAATGCATACAACTTCATTCTTAGCC TCAAGCACTGAATTAGACTCCATGTCTACTCCCCATGGCCGTATAACTGTCATTGGAACC AGCCTGGTCACTCCATCCTCTGATGCTTCAGCTGTAAAGACAGAGACCAGTACAAGTGAA AGAACATTGAGTCCTTCAGACACAACTGCATCTACTCCCATCTCAACTTTTTCTCGTGTC CAGAGGATGAGCATCTCAGTTCCTGACATTTTAAGTACAAGTTGGACTCCCAGTAGTACA GAAGCAGAAGATGTGCCTGTTTCAATGGTTTCTACAGATCATGCTAGTACAAAGACTGAC CCAAATACGCCCCTGTCCACTTTTCTGTTTGATTCTCTGTCCACTCTTGACTGGGACACT GGGAGATCTCTGTCATCAGCCACAGCCACTACCTCAGCTCCTCAGGGGGCCACAACTCCC CAGGAACTCACTTTGGAAACCATGATCAGCCCAGCTACCTCACAGTTGCCCTTCTCTATA GGGCACATTACAAGTGCAGTCACACCAGCTGCAATGGCAAGGAGCTCTGGAGTTACTTTT TCAAGACCAGATCCCACAAGCAAAAAGGCAGAGCAGACTTCCACTCAGCTTCCCACCACC ACTTCTGCACATCCAGGGCAGGTGCCCAGATCAGCAGCAACAACTCTGGATGTGATCCCA CACACAGCAAAAACTCCAGATGCAACTTTTCAGAGACAAGGGCAGACAGCTCTTACAACA GAGGCAAGAGCTACATCTGACTCCTGGAATGAGAAAGAAAAATCAACCCCAAGTGCACCT TGGATCACTGAGATGATGAATTCTGTCTCAGAAGATACCATCAAGGAGGTTACCAGCTCC TCCAGTGTATTAAGGACCCTGAATACGCTGGACATAAACTTGGAATCTGGGACGACTTCA TCCCCAAGTTGGAAAAGCAGCCCATATGAGAGAATTGCCCCTTCTGAGTCCACCACAGAC AAAGAGGCAATTCACCCTTCTACAAACACAGTAGAGACCACAGGCTGGGTCACAAGTTCC GAACATGCTTCTCATTCCACTATCCCAGCCCACTCAGCGTCATCCAAACTCACATCTCCA GTGGTTACAACCTCCACCAGGGAACAAGCAATAGTTTCTATGTCAACAACCACATGGCCA GAGTCTACAAGGGCTAGAACAGAGCCTAATTCCTTCTTGACTATTGAACTGAGGGACGTC AGCCCTTACATGGACACCAGCTCAACCACACAAACAAGTATTATCTCTTCCCCAGGTTCC ACTGCGATCACCAAGGGGCCTAGAACAGAAATTACCTCCTCTAAGAGAATATCCAGCTCA TTCCTTGCCCAGTCTATGAGGTCGTCAGACAGCCCCTCAGAAGCCATCACCAGGCTGTCT AACTTTCCTGCCATGACAGAATCTGGAGGAATGATCCTTGCTATGCAAACAAGTCCACCT GGCGCTACATCACTAAGTGCACCTACTTTGGATACATCAGCCACAGCCTCCTGGACAGGG ACTCCACTGGCTACGACTCAGAGATTTACATACTCAGAGAAGACCACTCTCTTTAGCAAA GGTCCTGAGGATACATCACAGCCAAGCCCTCCCTCTGTGGAAGAAACCAGCTCTTCCTCT TCCCTGGTACCTATCCATGCTACAACCTCGCCTTCCAATATTTTGTTGACATCACAAGGG CACAGTCCCTCCTCTACTCCACCTGTGACCTCAGTTTTCTTGTCTGAGACCTCTGGCCTG GGGAAGACCACAGACATGTCGAGGATAAGCTTGGAACCTGGCACAAGTTTACCTCCCAAT TTGAGCAGTACAGCAGGTGAGGCGTTATCCACTTATGAAGCCTCCAGAGATACAAAGGCA ATTCATCATTCTGCAGACACAGCAGTGACGAATATGGAGGCAACCAGTTCTGAATATTCT CCTATCCCAGGCCATACAAAGCCATCCAAAGCCACATCTCCATTGGTTACCTCCCACATC ATGGGGGACATCACTTCTTCCACATCAGTATTTGGCTCCTCCGAGACCACAGAGATTGAG ACAGTGTCCTCTGTGAACCAGGGACTTCAGGAGAGAAGCACATCCCAGGTGGCCAGCTCT GCTACAGAGACAAGCACTGTCATTACCCATGTGTCTAGTGGTGATGCTACTACTCATGTC ACCAAGACACAAGCCACTTTCTCTAGCGGAACATCCATCTCAAGCCCTCATCAGTTTATA ACTTCTACCAACACATTTACAGATGTGAGCACCAACCCCTCCACCTCTCTGATAATGACA GAATCTTCAGGAGTGACCATCACCACCCAAACAGGTCCTACTGGAGCTGCAACACAGGGT CCATATCTCTTGGACACATCAACCATGCCTTACTTGACAGAGACTCCATTAGCTGTGACT CCAGATTTTATGCAATCAGAGAAGACCACTCTCATAAGCAAAGGTCCCAAGGATGTGTCC TGGACAAGCCCTCCCTCTGTGGCAGAAACCAGCTATCCCTCTTCCCTGACACCTTTCTTG GTCACAACCATACCTCCTGCCACTTCCACGTTACAAGGGCAACATACATCCTCTCCTGTT TCTGCGACTTCAGTTCTTACCTCTGGACTGGTGAAGACCACAGATATGTTGAACACAAGC ATGGAACCTGTGACCAATTCACCTCAAAATTTGAACAATCCATCAAATGAGATACTGGCC ACTTTGGCAGCCACCACAGATATAGAGACTATTCATCCTTCCATAAACAAAGCAGTGACC AATATGGGGACTGCCAGTTCAGCACATGTACTGCATTCCACTCTCCCAGTCAGCTCAGAA CCATCTACAGCCACATCTCCAATGGTTCCTGCCTCCAGCATGGGGGACGCTCTTGCTTCT ATATCAATACCTGGTTCTGAGACCACAGACATTGAGGGAGAGCCAACATCCTCCCTGACT GCTGGACGAAAAGAGAACAGCACCCTCCAGGAGATGAACTCAACTACAGAGTCAAACATC ATCCTCTCCAATGTGTCTGTGGGGGCTATTACTGAAGCCACAAAAATGGAAGTCCCCTCT TTTGATGCAACATTCATACCAACTCCTGCTCAGTCAACAAAGTTCCCAGATATTTTCTCA GTAGCCAGCAGTAGACTTTCAAACTCTCCTCCCATGACAATATCTACCCACATGACCACC ACCCAGACAGGGTCTTCTGGAGCTACATCAAAGATTCCACTTGCCTTAGACACATCAACC TTGGAAACCTCAGCAGGGACTCCATCAGTGGTGACTGAGGGGTTTGCCCACTCAAAAATA ACCACTGCAATGAACAATGATGTCAAGGACGTGTCACAGACAAACCCTCCCTTTCAGGAT GAAGCCAGCTCTCCCTCTTCTCAAGCACCTGTCCTTGTCACAACCTTACCTTCTTCTGTT GCTTTCACACCGCAATGGCACAGTACCTCCTCTCCTGTTTCTATGTCCTCAGTTCTTACT TCTTCACTGGTAAAGACCGCAGGCAAGGTGGATACAAGCTTAGAAACAGTGACCAGTTCA CCTCAAAGTATGAGCAACACTTTGGATGACATATCGGTCACTTCAGCAGCCACCACAGAT ATAGAGACAACGCATCCTTCCATAAACACAGTAGTTACCAATGTGGGGACCACCGGTTCA GCATTTGAATCACATTCTACTGTCTCAGCTTACCCAGAGCCATCTAAAGTCACATCTCCA AATGTTACCACCTCCACCATGGAAGACACCACAATTTCCAGATCAATACCTAAATCCTCT AAGACTACAAGAACTGAGACTGAGACAACTTCCTCCCTGACTCCTAAACTGAGGGAGACC AGCATCTCCCAGGAGATCACCTCGTCCACAGAGACAAGCACTGTTCCTTACAAAGAGCTC ACTGGTGCCACTACCGAGGTATCCAGGACAGATGTCACTTCCTCTAGCAGTACATCCTTC CCTGGCCCTGATCAGTCCACAGTGTCACTAGACATCTCCACAGAAACCAACACCAGGCTG TCTACCTCCCCAATAATGACAGAATCTGCAGAAATAACCATCACCACCCAAACAGGTCCT CATGGGGCTACATCACAGGATACTTTTACCATGGACCCATCAAATACAACCCCCCAGGCA GGGATCCACTCAGCTATGACTCATGGATTTTCACAATTGGATGTGACCACTCTTATGAGC AGAATTCCACAGGATGTATCATGGACAAGTCCTCCCTCTGTGGATAAAACCAGCTCCCCC TCTTCCTTTCTGTCCTCACCTGCAATGACCACACCTTCCCTGATTTCTTCTACCTTACCA GAGGATAAGCTCTCCTCTCCTATGACTTCACTTCTCACCTCTGGCCTAGTGAAGATTACA GACATATTACGTACACGCTTGGAACCTGTGACCAGCTCACTTCCAAATTTCAGCAGCACC TCAGATAAGATACTGGCCACTTCTAAAGACAGTAAAGACACAAAGGAAATTTTTCCTTCT ATAAACACAGAAGAGACCAATGTGAAAGCCAACAACTCTGGACATGAATCCCATTCCCCT GCACTGGCTGACTCAGAGACACCCAAAGCCACAACTCAAATGGTTATCACCACCACTGTG GGAGATCCAGCTCCTTCCACATCAATGCCAGTGCATGGTTCCTCTGAGACTACAAACATT AAGAGAGAGCCAACATATTTCTTGACTCCTAGACTGAGAGAGACCAGTACCTCTCAGGAG TCCAGCTTTCCCACGGACACAAGTTTTCTACTTTCCAAAGTCCCCACTGGTACTATTACT GAGGTCTCCAGTACAGGGGTCAACTCTTCTAGCAAAATTTCCACCCCAGACCATGATAAG TCCACAGTGCCACCTGACACCTTCACAGGAGAGATCCCCAGGGTCTTCACCTCCTCTATT AAGACAAAATCTGCAGAAATGACGATCACCACCCAAGCAAGTCCTCCTGAGTCTGCATCG CACAGTACCCTTCCCTTGGACACATCAACCACACTTTCCCAGGGAGGGACTCATTCAACT GTGACTCAGGGATTCCCATACTCAGAGGTGACCACTCTCATGGGCATGGGTCCTGGGAAT GTGTCATGGATGACAACTCCCCCTGTGGAAGAAACCAGCTCTGTGTCTTCCCTGATGTCT TCACCTGCCATGACATCCCCTTCTCCTGTTTCCTCCACATCACCACAGAGCATCCCCTCC TCTCCTCTTCCTGTGACTGCACTTCCTACTTCTGTTCTGGTGACAACCACAGATGTGTTG GGCACAACAAGCCCAGAGTCTGTAACCAGTTCACCTCCAAATTTGAGCAGCATCACTCAT GAGAGACCGGCCACTTACAAAGACACTGCACACACAGAAGCCGCCATGCATCATTCCACA AACACCGCAGTGACCAATGTAGGGACTTCCGGGTCTGGACATAAATCACAATCCTCTGTC CTAGCTGACTCAGAGACATCGAAAGCCACACCTCTGATGAGTACCACCTCCACCCTGGGG GACACAAGTGTTTCCACATCAACTCCTAATATCTCTCAGACTAACCAAATTCAAACAGAG CCAACAGCATCCCTGAGCCCTAGACTGAGGGAGAGCAGCACGTCTGAGAAGACCAGCTCA ACAACAGAGACAAATACTGCCTTTTCTTATGTGCCCACAGGTGCTATTACTCAGGCCTCC AGAACAGAAATCTCCTCTAGCAGAACATCCATCTCAGACCTTGATCGGCCCACAATAGCA CCCGACATCTCCACAGGAATGATCACCAGGCTCTTCACCTCCCCCATCATGACAAAATCT GCAGAAATGACCGTCACCACTCAAACAACTACTCCTGGGGCTACATCACAGGGTATCCTT CCCTGGGACACATCAACCACACTTTTCCAGGGAGGGACTCATTCAACCGTGTCTCAGGGA TTCCCACACTCAGAGATAACCACTCTTCGGAGCAGAACCCCTGGAGATGTGTCATGGATG ACAACTCCCCCTGTGGAAGAAACCAGCTCTGGGTTTTCCCTGATGTCACCTTCCATGACA TCCCCTTCTCCTGTTTCCTCCACATCACCAGAGAGCATCCCCTCCTCTCCTCTCCCTGTG ACTGCACTTCTTACTTCTGTTCTGGTGACAACCACAAATGTATTGGGCACAACAAGCCCA GAGCCCGTAACGAGTTCACCTCCAAATTTAAGCAGCCCCACACAGGAGAGACTGACCACT TACAAAGACACTGCGCACACAGAAGCCATGCATGCTTCCATGCATACAAACACTGCAGTG GCCAACGTGGGGACCTCCATTTCTGGACATGAATCACAATCTTCTGTCCCAGCTGATTCA CACACATCCAAAGCCACATCTCCAATGGGTATCACCTTCGCCATGGGGGATACAAGTGTT TCTACATCAACTCCTGCCTTCTTTGAGACTAGAATTCAGACTGAATCAACATCCTCTTTG ATTCCTGGATTAAGGGACACCAGGACGTCTGAGGAGATCAACACTGTGACAGAGACCAGC ACTGTCCTTTCAGAAGTGCCCACTACTACTACTACTGAGGTCTCCAGGACAGAAGTTATC ACTTCCAGCAGAACAACCATCTCAGGGCCTGATCATTCCAAAATGTCACCCTACATCTCC ACAGAAACCATCACCAGGCTCTCCACTTTTCCTTTTGTAACAGGATCCACAGAAATGGCC ATCACCAACCAAACAGGTCCTATAGGGACTATCTCACAGGCTACCCTTACCCTGGACACA TCAAGCACAGCTTCCTGGGAAGGGACTCACTCACCTGTGACTCAGAGATTTCCACACTCA GAGGAGACCACTACTATGAGCAGAAGTACTAAGGGCGTGTCATGGCAAAGCCCTCCCTCT GTGGAAGAAACCAGTTCTCCTTCTTCCCCAGTGCCTTTACCTGCAATAACCTCACATTCA TCTCTTTATTCCGCAGTATCAGGAAGTAGCCCCACTTCTGCTCTCCCTGTGACTTCCCTT CTCACCTCTGGCAGGAGGAAGACCATAGACATGTTGGACACACACTCAGAACTTGTGACC AGCTCCTTACCAAGTGCAAGTAGCTTCTCAGGTGAGATACTCACTTCTGAAGCCTCCACA AATACAGAGACAATTCACTTTTCAGAGAACACAGCAGAAACCAATATGGGGACCACCAAT TCTATGCATAAACTACATTCCTCTGTCTCAATCCACTCCCAGCCATCCGGACACACACCT CCAAAGGTTACTGGATCTATGATGGAGGACGCTATTGTTTCCACATCAACACCTGGTTCT CCTGAGACTAAAAATGTTGACAGAGACTCAACATCCCCTCTGACTCCTGAACTGAAAGAG GACAGCACCGCCCTGGTGATGAACTCAACTACAGAGTCAAACACTGTTTTCTCCAGTGTG TCCCTGGATGCTGCTACTGAGGTCTCCAGGGCAGAAGTCACCTACTATGATCCTACATTC ATGCCAGCTTCTGCTCAGTCAACAAAGTCCCCAGACATTTCACCTGAAGCCAGCAGCAGT CATTCTAACTCTCCTCCCTTGACAATATCTACACACAAGACCATCGCCACACAAACAGGT CCTTCTGGGGTGACATCTCTTGGCCAACTGACCCTGGACACATCAACCATAGCCACCTCA GCAGGAACTCCATCAGCCAGAACTCAGGATTTTGTAGATTCAGAAACAACCAGTGTCATG AACAATGATCTCAATGATGTGTTGAAGACAAGCCCTTTCTCTGCAGAAGAAGCCAACTCT CTCTCTTCTCAGGCACCTCTCCTTGTGACAACCTCACCTTCTCCTGTAACTTCCACATTG CAAGAGCACAGTACCTCCTCTCTTGTTTCTGTGACCTCAGTACCCACCCCTACACTGGCG AAGATCACAGACATGGACACAAACTTAGAACCTGTGACTCGTTCACCTCAAAATTTAAGG AACACCTTGGCCACTTCAGAAGCCACCACAGATACACACACAATGCATCCTTCTATAAAC ACAGCAGTGGCCAATGTGGGGACCACCAGTTCACCAAATGAATTCTATTTTACTGTCTCA CCTGACTCAGACCCATATAAAGCCACATCCGCAGTAGTTATCACTTCCACCTCGGGGGAC TCAATAGTTTCCACATCAATGCCTAGATCCTCTGCGATGAAAAAGATTGAGTCTGAGACA ACTTTCTCCCTGATATTTAGACTGAGGGAGACTAGCACCTCCCAGAAAATTGGCTCATCC TCAGACACAAGCACGGTCTTTGACAAAGCATTCACTGCTGCTACTACTGAGGTCTCCAGA ACAGAACTCACCTCCTCTAGCAGAACATCCATCCAAGGCACTGAAAAGCCCACAATGTCA CCGGACACCTCCACAAGATCTGTCACCATGCTTTCTACTTTTGCTGGCCTGACAAAATCC GAAGAAAGGACCATTGCCACCCAAACAGGTCCTCATAGGGCGACATCACAGGGTACCCTT ACCTGGGACACATCAATCACAACCTCACAGGCAGGGACCCACTCAGCTATGACTCATGGA TTTTCACAATTAGATTTGTCCACTCTTACGAGTAGAGTTCCTGAGTACATATCAGGGACA AGCCCACCCTCTGTGGAAAAAACCAGCTCTTCCTCTTCCCTTCTGTCTTTACCAGCAATA ACCTCACCGTCCCCTGTACCTACTACATTACCAGAAAGTAGGCCGTCTTCTCCTGTTCAT CTGACTTCACTCCCCACCTCTGGCCTAGTGAAGACCACAGATATGCTGGCATCTGTGGCC AGTTTACCTCCAAACTTGGGCAGCACCTCACATAAGATACCGACTACTTCAGAAGACATT AAAGATACAGAGAAAATGTATCCTTCCACAAACATAGCAGTAACCAATGTGGGGACCACC ACTTCTGAAAAGGAATCTTATTCGTCTGTCCCAGCCTACTCAGAACCACCCAAAGTCACC TCTCCAATGGTTACCTCTTTCAACATAAGGGACACCATTGTTTCCACATCCATGCCTGGC TCCTCTGAGATTACAAGGATTGAGATGGAGTCAACATTCTCCCTGGCTCATGGGCTGAAG GGAACCAGCACCTCCCAGGACCCCATCGTATCCACAGAGAAAAGTGCTGTCCTTCACAAG TTGACCACTGGTGCTACTGAGACCTCTAGGACAGAAGTTGCCTCTTCTAGAAGAACATCC ATTCCAGGCCCTGATCATTCCACAGAGTCACCAGACATCTCCACTGAAGTGATCCCCAGC CTGCCTATCTCCCTTGGCATTACAGAATCTTCAAATATGACCATCATCACTCGAACAGGT CCTCCTCTTGGCTCTACATCACAGGGCACATTTACCTTGGACACACCAACTACATCCTCC AGGGCAGGAACACACTCGATGGCGACTCAGGAATTTCCACACTCAGAAATGACCACTGTC ATGAACAAGGACCCTGAGATTCTATCATGGACAATCCCTCCTTCTATAGAGAAAACCAGC TTCTCCTCTTCCCTGATGCCTTCACCAGCCATGACTTCACCTCCTGTTTCCTCAACATTA CCAAAGACCATTCACACCACTCCTTCTCCTATGACCTCACTGCTCACCCCTAGCCTAGTG ATGACCACAGACACATTGGGCACAAGCCCAGAACCTACAACCAGTTCACCTCCAAATTTG AGCAGTACCTCACATGAGATACTGACAACAGATGAAGACACCACAGCTATAGAAGCCATG CATCCTTCCACAAGCACAGCAGCGACTAATGTGGAAACCACCAGTTCTGGACATGGGTCA CAATCCTCTGTCCTAGCTGACTCAGAAAAAACCAAGGCCACAGCTCCAATGGATACCACC TCCACCATGGGGCATACAACTGTTTCCACATCAATGTCTGTTTCCTCTGAGACTACAAAA ATTAAGAGAGAGTCAACATATTCCTTGACTCCTGGACTGAGAGAGACCAGCATTTCCCAA AATGCCAGCTTTTCCACTGACACAAGTATTGTTCTTTCAGAAGTCCCCACTGGTACTACT GCTGAGGTCTCCAGGACAGAAGTCACCTCCTCTGGTAGAACATCCATCCCTGGCCCTTCT CAGTCCACAGTTTTGCCAGAAATATCCACAAGAACAATGACAAGGCTCTTTGCCTCGCCC ACCATGACAGAATCAGCAGAAATGACCATCCCCACTCAAACAGGTCCTTCTGGGTCTACC TCACAGGATACCCTTACCTTGGACACATCCACCACAAAGTCCCAGGCAAAGACTCATTCA ACTTTGACTCAGAGATTTCCACACTCAGAGATGACCACTCTCATGAGCAGAGGTCCTGGA GATATGTCATGGCAAAGCTCTCCCTCTCTGGAAAATCCCAGCTCTCTCCCTTCCCTGCTG TCTTTACCTGCCACAACCTCACCTCCTCCCATTTCCTCCACATTACCAGTGACTATCTCC TCCTCTCCTCTTCCTGTGACTTCACTTCTCACCTCTAGCCCGGTAACGACCACAGACATG TTACACACAAGCCCAGAACTTGTAACCAGTTCACCTCCAAAGCTGAGCCACACTTCAGAT GAGAGACTGACCACTGGCAAGGACACCACAAATACAGAAGCTGTGCATCCTTCCACAAAC ACAGCAGCGTCCAATGTGGAGATTCCCAGCTCTGGACATGAATCCCCTTCCTCTGCCTTA GCTGACTCAGAGACATCCAAAGCCACATCACCAATGTTTATTACCTCCACCCAGGAGGAT ACAACTGTTGCCATATCAACCCCTCACTTCTTGGAGACTAGCAGAATTCAGAAAGAGTCA ATTTCCTCCCTGAGCCCTAAATTGAGGGAGACAGGCAGTTCTGTGGAGACAAGCTCAGCC ATAGAGACAAGTGCTGTCCTTTCTGAAGTGTCCATTGGTGCTACTACTGAGATCTCCAGG ACAGAAGTCACCTCCTCTAGCAGAACATCCATCTCTGGTTCTGCTGAGTCCACAATGTTG CCAGAAATATCCACCACAAGAAAAATCATTAAGTTCCCTACTTCCCCCATCCTGGCAGAA TCATCAGAAATGACCATCAAGACCCAAACAAGTCCTCCTGGGTCTACATCAGAGAGTACC TTTACATTAGACACATCAACCACTCCCTCCTTGGTAATAACCCATTCGACTATGACTCAG AGATTGCCACACTCAGAGATAACCACTCTTGTGAGTAGAGGTGCTGGGGATGTGCCACGG CCCAGCTCTCTCCCTGTGGAAGAAACAAGCCCTCCATCTTCCCAGCTGTCTTTATCTGCC ATGATCTCACCTTCTCCTGTTTCTTCCACATTACCAGCAAGTAGCCACTCCTCTTCTGCT TCTGTGACTTCACTTCTCACACCAGGCCAAGTGAAGACTACTGAGGTGTTGGACGCAAGT GCAGAACCTGAAACCAGTTCACCTCCAAGTTTGAGCAGCACCTCAGTTGAAATACTGGCC ACCTCTGAAGTCACCACAGATACGGAGAAAATTCATCCTTTCTCAAACACGGCAGTAACC AAAGTTGGAACTTCCAGTTCTGGACATGAATCCCCTTCCTCTGTCCTACCTGACTCAGAG ACAACCAAAGCCACATCGGCAATGGGTACCATCTCCATTATGGGGGATACAAGTGTTTCT ACATTAACTCCTGCCTTATCTAACACTAGGAAAATTCAGTCAGAGCCAGCTTCCTCACTG ACCACCAGATTGAGGGAGACCAGCACCTCTGAAGAGACCAGCTTAGCCACAGAAGCAAAC ACTGTTCTTTCTAAAGTGTCCACTGGTGCTACTACTGAGGTCTCCAGGACAGAAGCCATC TCCTTTAGCAGAACATCCATGTCAGGCCCTGAGCAGTCCACAATGTCACAAGACATCTCC ATAGGAACCATCCCCAGGATTTCTGCCTCCTCTGTCCTGACAGAATCTGCAAAAATGACC ATCACAACCCAAACAGGTCCTTCGGAGTCTACACTAGAAAGTACCCTTAATTTGAACACA GCAACCACACCCTCTTGGGTGGAAACCCACTCTATAGTAATTCAGGGATTTCCACACCCA GAGATGACCACTTCCATGGGCAGAGGTCCTGGAGGTGTGTCATGGCCTAGCCCTCCCTTT GTGAAAGAAACCAGCCCTCCATCCTCCCCGCTGTCTTTACCTGCCGTGACCTCACCTCAT CCTGTTTCCACCACATTCCTAGCACATATCCCCCCCTCTCCCCTTCCTGTGACTTCACTT CTCACCTCTGGCCCGGCGACAACCACAGATATCTTGGGTACAAGCACAGAACCTGGAACC AGTTCATCTTCAAGTTTGAGCACCACCTCCCATGAGAGACTGACCACTTACAAAGACACT GCACATACAGAAGCCGTGCATCCTTCCACAAACACAGGAGGGACCAATGTGGCAACCACC AGCTCTGGATATAAATCACAGTCCTCTGTCCTAGCTGACTCATCTCCAATGTGTACCACC TCCACCATGGGGGATACAAGTGTTCTCACATCAACTCCTGCCTTCCTTGAGACTAGGAGG ATTCAGACAGAGCTAGCTTCCTCCCTGACCCCTGGATTGAGGGAGTCCAGCGGCTCTGAA GGGACCAGCTCAGGCACCAAGATGAGCACTGTCCTCTCTAAAGTGCCCACTGGTGCTACT ACTGAGATCTCCAAGGAAGACGTCACCTCCATCCCAGGTCCCGCTCAATCCACAATATCA CCAGACATCTCCACAAGAACCGTCAGCTGGTTCTCTACATCCCCTGTCATGACAGAATCA GCAGAAATAACCATGAACACCCATACAAGTCCTTTAGGGGCCACAACACAAGGCACCAGT ACTTTGGACACGTCAAGCACAACCTCTTTGACAATGACACACTCAACTATATCTCAAGGA TTTTCACACTCACAGATGAGCACTCTTATGAGGAGGGGTCCTGAGGATGTATCATGGATG AGCCCTCCCCTTCTGGAAAAAACTAGACCTTCCTTTTCTCTGATGTCTTCACCAGCCACA ACTTCACCTTCTCCTGTTTCCTCCACATTACCAGAGAGCATCTCTTCCTCTCCTCTTCCT GTGACTTCACTCCTCACGTCTGGCTTGGCAAAAACTACAGATATGTTGCACAAAAGCTCA GAACCTGTAACCAACTCACCTGCAAATTTGAGCAGCACCTCAGTTGAAATACTGGCCACC TCTGAAGTCACCACAGATACAGAGAAAACTCATCCTTCTTCAAACAGAACAGTGACCGAT GTGGGGACCTCCAGTTCTGGACATGAATCCACTTCCTTTGTCCTAGCTGACTCACAGACA TCCAAAGTCACATCTCCAATGGTTATTACCTCCACCATGGAGGATACGAGTGTCTCCACA TCAACTCCTGGCTTTTTTGAGACTAGCAGAATTCAGACAGAACCAACATCCTCCCTGACC CTTGGACTGAGAAAGACCAGCAGCTCTGAGGGGACCAGCTTAGCCACAGAGATGAGCACT GTCCTTTCTGGAGTGCCCACTGGTGCCACTGCTGAAGTCTCCAGGACAGAAGTCACCTCC TCTAGCAGAACATCCATCTCAGGCTTTGCTCAGCTCACAGTGTCACCAGAGACTTCCACA GAAACCATCACCAGACTCCCTACCTCCAGCATAATGACAGAATCAGCAGAAATGATGATC AAGACACAAACAGATCCTCCTGGGTCTACACCAGAGAGTACTCATACTGTGGACATATCA ACAACACCCAACTGGGTAGAAACCCACTCGACTGTGACTCAGAGATTTTCACACTCAGAG ATGACCACTCTTGTGAGCAGAAGCCCTGGTGATATGTTATGGCCTAGTCAATCCTCTGTG GAAGAAACCAGCTCTGCCTCTTCCCTGCTGTCTCTGCCTGCCACGACCTCACCTTCTCCT GTTTCCTCTACATTAGTAGAGGATTTCCCTTCCGCTTCTCTTCCTGTGACTTCTCTTCTC AACCCTGGCCTGGTGATAACCACAGACAGGATGGGCATAAGCAGAGAACCTGGAACCAGT TCCACTTCAAATTTGAGCAGCACCTCCCATGAGAGACTGACCACTTTGGAAGACACTGTA GATACAGAAGACATGCAGCCTTCCACACACACAGCAGTGACCAACGTGAGGACCTCCATT TCTGGACATGAATCACAATCTTCTGTCCTATCTGACTCAGAGACACCCAAAGCCACATCT CCAATGGGTACCACCTACACCATGGGGGAAACGAGTGTTTCCATATCCACTTCTGACTTC TTTGAGACCAGCAGAATTCAGATAGAACCAACATCCTCCCTGACTTCTGGATTGAGGGAG ACCAGCAGCTCTGAGAGGATCAGCTCAGCCACAGAGGGAAGCACTGTCCTTTCTGAAGTG CCCAGTGGTGCTACCACTGAGGTCTCCAGGACAGAAGTGATATCCTCTAGGGGAACATCC ATGTCAGGGCCTGATCAGTTCACCATATCACCAGACATCTCTACTGAAGCGATCACCAGG CTTTCTACTTCCCCCATTATGACAGAATCAGCAGAAAGTGCCATCACTATTGAGACAGGT TCTCCTGGGGCTACATCAGAGGGTACCCTCACCTTGGACACCTCAACAACAACCTTTTGG TCAGGGACCCACTCAACTGCATCTCCAGGATTTTCACACTCAGAGATGACCACTCTTATG AGTAGAACTCCTGGAGATGTGCCATGGCCGAGCCTTCCCTCTGTGGAAGAAGCCAGCTCT GTCTCTTCCTCACTGTCTTCACCTGCCATGACCTCAACTTCTTTTTTCTCCACATTACCA GAGAGCATCTCCTCCTCTCCTCATCCTGTGACTGCACTTCTCACCCTTGGCCCAGTGAAG ACCACAGACATGTTGCGCACAAGCTCAGAACCTGAAACCAGTTCACCTCCAAATTTGAGC AGCACCTCAGCTGAAATATTAGCCACGTCTGAAGTCACCAAAGATAGAGAGAAAATTCAT CCCTCCTCAAACACACCTGTAGTCAATGTAGGGACTGTGATTTATAAACATCTATCCCCT TCCTCTGTTTTGGCTGACTTAGTGACAACAAAACCCACATCTCCAATGGCTACCACCTCC ACTCTGGGGAATACAAGTGTTTCCACATCAACTCCTGCCTTCCCAGAAACTATGATGACA CAGCCAACTTCCTCCCTGACTTCTGGATTAAGGGAGATCAGTACCTCTCAAGAGACCAGC TCAGCAACAGAGAGAAGTGCTTCTCTTTCTGGAATGCCCACTGGTGCTACTACTAAGGTC TCCAGAACAGAAGCCCTCTCCTTAGGCAGAACATCCACCCCAGGTCCTGCTCAATCCACA ATATCACCAGAAATCTCCACGGAAACCATCACTAGAATTTCTACTCCCCTCACCACGACA GGATCAGCAGAAATGACCATCACCCCCAAAACAGGTCATTCTGGGGCATCCTCACAAGGT ACCTTTACCTTGGACACATCAAGCAGAGCCTCCTGGCCAGGAACTCACTCAGCTGCAACT CACAGATCTCCACACTCAGGGATGACCACTCCTATGAGCAGAGGTCCTGAGGATGTGTCA TGGCCAAGCCGCCCATCAGTGGAAAAAACTAGCCCTCCATCTTCCCTGGTGTCTTTATCT GCAGTAACCTCACCTTCGCCACTTTATTCCACACCATCTGAGAGTAGCCACTCATCTCCT CTCCGGGTGACTTCTCTTTTCACCCCTGTCATGATGAAGACCACAGACATGTTGGACACA AGCTTGGAACCTGTGACCACTTCACCTCCCAGTATGAATATCACCTCAGATGAGAGTCTG GCCACTTCTAAAGCCACCATGGAGACAGAGGCAATTCAGCTTTCAGAAAACACAGCTGTG ACTCAGATGGGCACCATCAGCGCTAGACAAGAATTCTATTCCTCTTATCCAGGCCTCCCA GAGCCATCCAAAGTGACATCTCCAGTGGTCACCTCTTCCACCATAAAAGACATTGTTTCT ACAACCATACCTGCTTCCTCTGAGATAACAAGAATTGAGATGGAGTCAACATCCACCCTG ACCCCCACACCAAGGGAGACCAGCACCTCCCAGGAGATCCACTCAGCCACAAAGCCAAGC ACTGTTCCTTACAAGGCACTCACTAGTGCCACGATTGAGGACTCCATGACACAAGTCATG TCCTCTAGCAGAGGACCTAGCCCTGATCAGTCCACAATGTCACAAGACATATCCACTGAA GTGATCACCAGGCTCTCTACCTCCCCCATCAAGACAGAATCTACAGAAATGACCATTACC ACCCAAACAGGTTCTCCTGGGGCTACATCAAGGGGTACCCTTACCTTGGACACTTCAACA ACTTTTATGTCAGGGACCCACTCAACTGCATCTCAAGGATTTTCACACTCACAGATGACC GCTCTTATGAGTAGAACTCCTGGAGATGTGCCATGGCTAAGCCATCCCTCTGTGGAAGAA GCCAGCTCTGCCTCTTTCTCACTGTCTTCACCTGTCATGACCTCATCTTCTCCCGTTTCT TCCACATTACCAGACAGCATCCACTCTTCTTCGCTTCCTGTGACATCACTTCTCACCTCA GGGCTGGTGAAGACCACAGAGCTGTTGGGCACAAGCTCAGAACCTGAAACCAGTTCACCC CCAAATTTGAGCAGCACCTCAGCTGAAATACTGGCCATCACTGAAGTCACTACAGATACA GAGAAACTGGAGATGACCAATGTGGTAACCTCAGGTTATACACATGAATCTCCTTCCTCT GTCCTAGCTGACTCAGTGACAACAAAGGCCACATCTTCAATGGGTATCACCTACCCCACA GGAGATACAAATGTTCTCACATCAACCCCTGCCTTCTCTGACACCAGTAGGATTCAAACA AAGTCAAAGCTCTCACTGACTCCTGGGTTGATGGAGACCAGCATCTCTGAAGAGACCAGC TCTGCCACAGAAAAAAGCACTGTCCTTTCTAGTGTGCCCACTGGTGCTACTACTGAGGTC TCCAGGACAGAAGCCATCTCTTCTAGCAGAACATCCATCCCAGGCCCTGCTCAATCCACA ATGTCATCAGACACCTCCATGGAAACCATCACTAGAATTTCTACCCCCCTCACAAGGAAA GAATCAACAGACATGGCCATCACCCCCAAAACAGGTCCTTCTGGGGCTACCTCGCAGGGT ACCTTTACCTTGGACTCATCAAGCACAGCCTCCTGGCCAGGAACTCACTCAGCTACAACT CAGAGATTTCCACAGTCAGTGGTGACAACTCCTATGAGCAGAGGTCCTGAGGATGTGTCA TGGCCAAGCCCGCTGTCTGTGGAAAAAAACAGCCCTCCATCTTCCCTGGTATCTTCATCT TCAGTAACCTCACCTTCGCCACTTTATTCCACACCATCTGGGAGTAGCCACTCCTCTCCT GTCCCTGTCACTTCTCTTTTCACCTCTATCATGATGAAGGCCACAGACATGTTGGATGCA AGTTTGGAACCTGAGACCACTTCAGCTCCCAATATGAATATCACCTCAGATGAGAGTCTG GCCGCTTCTAAAGCCACCACGGAGACAGAGGCAATTCACGTTTTTGAAAATACAGCAGCG TCCCATGTGGAAACCACCAGTGCTACAGAGGAACTCTATTCCTCTTCCCCAGGCTTCTCA GAGCCAACAAAAGTGATATCTCCAGTGGTCACCTCTTCCTCTATAAGAGACAACATGGTT TCCACAACAATGCCTGGCTCCTCTGGCATTACAAGGATTGAGATAGAGTCAATGTCATCT CTGACCCCTGGACTGAGGGAGACCAGAACCTCCCAGGACATCACCTCATCCACAGAGACA AGCACTGTCCTTTACAAGATGCCCTCTGGTGCCACTCCTGAGGTCTCCAGGACAGAAGTT ATGCCCTCTAGCAGAACATCCATTCCTGGCCCTGCTCAGTCCACAATGTCACTAGACATC TCCGATGAAGTTGTCACCAGGCTGTCTACCTCTCCCATCATGACAGAATCTGCAGAAATA ACCATCACCACCCAAACAGGTTATTCTCTGGCTACATCCCAGGTTACCCTTCCCTTGGGC ACCTCAATGACCTTTTTGTCAGGGACCCACTCAACTATGTCTCAAGGACTTTCACACTCA GAGATGACCAATCTTATGAGCAGGGGTCCTGAAAGTCTGTCATGGACGAGCCCTCGCTTT GTGGAAACAACTAGATCTTCCTCTTCTCTGACATCATTACCTCTCACGACCTCACTTTCT CCTGTGTCCTCCACATTACTAGACAGTAGCCCCTCCTCTCCTCTTCCTGTGACTTCACTT ATCCTCCCAGGCCTGGTGAAGACTACAGAAGTGTTGGATACAAGCTCAGAGCCTAAAACC AGTTCATCTCCAAATTTGAGCAGCACCTCAGTTGAAATACCGGCCACCTCTGAAATCATG ACAGATACAGAGAAAATTCATCCTTCCTCAAACACAGCGGTGGCCAAAGTGAGGACCTCC AGTTCTGTTCATGAATCTCATTCCTCTGTCCTAGCTGACTCAGAAACAACCATAACCATA CCTTCAATGGGTATCACCTCCGCTGTGGACGATACCACTGTTTTCACATCAAATCCTGCC TTCTCTGAGACTAGGAGGATTCCGACAGAGCCAACATTCTCATTGACTCCTGGATTCAGG GAGACTAGCACCTCTGAAGAGACCACCTCAATCACAGAAACAAGTGCAGTCCTTTATGGA GTGCCCACTAGTGCTACTACTGAAGTCTCCATGACAGAAATCATGTCCTCTAATAGAATA CACATCCCTGACTCTGATCAGTCCACGATGTCTCCAGACATCATCACTGAAGTGATCACC AGGCTCTCTTCCTCATCCATGATGTCAGAATCAACACAAATGACCATCACCACCCAAAAA AGTTCTCCTGGGGCTACAGCACAGAGTACTCTTACCTTGGCCACAACAACAGCCCCCTTG GCAAGGACCCACTCAACTGTTCCTCCTAGATTTTTACACTCAGAGATGACAACTCTTATG AGTAGGAGTCCTGAAAATCCATCATGGAAGAGCTCTCTCTTTGTGGAAAAAACTAGCTCT TCATCTTCTCTGTTGTCCTTACCTGTCACGACCTCACCTTCTGTTTCTTCCACATTACCG CAGAGTATCCCTTCCTCCTCTTTTTCTGTGACTTCACTCCTCACCCCAGGCATGGTGAAG ACTACAGACACAAGCACAGAACCTGGAACCAGTTTATCTCCAAATCTGAGTGGCACCTCA GTTGAAATACTGGCTGCCTCTGAAGTCACCACAGATACAGAGAAAATTCATCCTTCTTCA AGCATGGCAGTGACCAATGTGGGAACCACCAGTTCTGGACATGAACTATATTCCTCTGTT TCAATCCACTCGGAGCCATCCAAGGCTACATACCCAGTGGGTACTCCCTCTTCCATGGCT GAAACCTCTATTTCCACATCAATGCCTGCTAATTTTGAGACCACAGGATTTGAGGCTGAG CCATTTTCTCATTTGACTTCTGGATTTAGGAAGACAAACATGTCCCTGGACACCAGCTCA GTCACACCAACAAATACACCTTCTTCTCCTGGGTCCACTCACCTTTTACAGAGTTCCAAG ACTGATTTCACCTCTTCTGCAAAAACATCATCCCCAGACTGGCCTCCAGCCTCACAGTAT ACTGAAATTCCAGTGGACATAATCACCCCCTTTAATGCTTCTCCATCTATTACGGAGTCC ACTGGGATAACCTCCTTCCCAGAATCCAGGTTTACTATGTCTGTAACAGAAAGTACTCAT CATCTGAGTACAGATTTGCTGCCTTCAGCTGAGACTATTTCCACTGGCACAGTGATGCCT TCTCTATCAGAGGCCATGACTTCATTTGCCACCACTGGAGTTCCACGAGCCATCTCAGGT TCAGGTAGTCCATTCTCTAGGACAGAGTCAGGCCCTGGGGATGCTACTCTGTCCACCATT GCAGAGAGCCTGCCTTCATCCACTCCTGTGCCATTCTCCTCTTCAACCTTCACTACCACT GATTCTTCAACCATCCCAGCCCTCCATGAGATAACTTCCTCTTCAGCTACCCCATATAGA GTGGACACCAGTCTTGGGACAGAGAGCAGCACTACTGAAGGACGCTTGGTTATGGTCAGT ACTTTGGACACTTCAAGCCAACCAGGCAGGACATCTTCATCACCCATTTTGGATACCAGA ATGACAGAGAGCGTTGAGCTGGGAACAGTGACAAGTGCTTATCAAGTTCCTTCACTCTCA ACACGGTTGACAAGAACTGATGGCATTATGGAACACATCACAAAAATACCCAATGAAGCA GCACACAGAGGTACCATAAGACCAGTCAAAGGCCCTCAGACATCCACTTCGCCTGCCAGT CCTAAAGGACTACACACAGGAGGGACAAAAAGAATGGAGACCACCACCACAGCTCTGAAG ACCACCACCACAGCTCTGAAGACCACTTCCAGAGCCACCTTGACCACCAGTGTCTATACT CCCACTTTGGGAACACTGACTCCCCTCAATGCATCAATGCAAATGGCCAGCACAATCCCC ACAGAAATGATGATCACAACCCCATATGTTTTCCCTGATGTTCCAGAAACGACATCCTCA TTGGCTACCAGCCTGGGAGCAGAAACCAGCACAGCTCTTCCCAGGACAACCCCATCTGTT TTCAATAGAGAATCAGAGACCACAGCCTCACTGGTCTCTCGTTCTGGGGCAGAGAGAAGT CCGGTTATTCAAACTCTAGATGTTTCTTCTAGTGAGCCAGATACAACAGCTTCATGGGTT ATCCATCCTGCAGAGACCATCCCAACTGTTTCCAAGACAACCCCCAATTTTTTCCACAGT GAATTAGACACTGTATCTTCCACAGCCACCAGTCATGGGGCAGACGTCAGCTCAGCCATT CCAACAAATATCTCACCTAGTGAACTAGATGCACTGACCCCACTGGTCACTATTTCGGGG ACAGATACTAGTACAACATTCCCAACACTGACTAAGTCCCCACATGAAACAGAGACAAGA ACCACATGGCTCACTCATCCTGCAGAGACCAGCTCAACTATTCCCAGAACAATCCCCAAT TTTTCTCATCATGAATCAGATGCCACACCTTCAATAGCCACCAGTCCTGGGGCAGAAACC AGTTCAGCTATTCCAATTATGACTGTCTCACCTGGTGCAGAAGATCTGGTGACCTCACAG GTCACTAGTTCTGGGACAGACAGAAATATGACTATTCCAACTTTGACTCTTTCTCCTGGT GAACCAAAGACGATAGCCTCATTAGTCACCCATCCTGAAGCACAGACAAGTTCGGCCATT CCAACTTCAACTATCTCGCCTGCTGTATCACGGTTGGTGACCTCAATGGTCACCAGTTTG GCGGCAAAGACAAGTACAACTAATCGAGCTCTGACAAACTCCCCTGGTGAACCAGCTACA ACAGTTTCATTGGTCACGCATCCTGCACAGACCAGCCCAACAGTTCCCTGGACAACTTCC ATTTTTTTCCATAGTAAATCAGACACCACACCTTCAATGACCACCAGTCATGGGGCAGAA TCCAGTTCAGCTGTTCCAACTCCAACTGTTTCAACTGAGGTACCAGGAGTAGTGACCCCT TTGGTCACCAGTTCTAGGGCAGTGATCAGTACAACTATTCCAATTCTGACTCTTTCTCCT GGTGAACCAGAGACCACACCTTCAATGGCCACCAGTCATGGGGAAGAAGCCAGTTCTGCT ATTCCAACTCCAACTGTTTCACCTGGGGTACCAGGAGTGGTGACCTCTCTGGTCACTAGT TCTAGGGCAGTGACTAGTACAACTATTCCAATTCTGACTTTTTCTCTTGGTGAACCAGAG ACCACACCTTCAATGGCCACCAGTCATGGGACAGAAGCTGGCTCAGCTGTTCCAACTGTT TTACCTGAGGTACCAGGAATGGTGACCTCTCTGGTTGCTAGTTCTAGGGCAGTAACCAGT ACAACTCTTCCAACTCTGACTCTTTCTCCTGGTGAACCAGAGACCACACCTTCAATGGCC ACCAGTCATGGGGCAGAAGCCAGCTCAACTGTTCCAACTGTTTCACCTGAGGTACCAGGA GTGGTGACCTCTCTGGTCACTAGTTCTAGTGGAGTAAACAGTACAAGTATTCCAACTCTG ATTCTTTCTCCTGGTGAACTAGAAACCACACCTTCAATGGCCACCAGTCATGGGGCAGAA GCCAGCTCAGCTGTTCCAACTCCAACTGTTTCACCTGGGGTATCAGGAGTGGTGACCCCT CTGGTCACTAGTTCCAGGGCAGTGACCAGTACAACTATTCCAATTCTAACTCTTTCTTCT AGTGAGCCAGAGACCACACCTTCAATGGCCACCAGTCATGGGGTAGAAGCCAGCTCAGCT GTTCTAACTGTTTCACCTGAGGTACCAGGAATGGTGACCTCTCTGGTCACTAGTTCTAGA GCAGTAACCAGTACAACTATTCCAACTCTGACTATTTCTTCTGATGAACCAGAGACCACA ACTTCATTGGTCACCCATTCTGAGGCAAAGATGATTTCAGCCATTCCAACTTTAGCTGTC TCCCCTACTGTACAAGGGCTGGTGACTTCACTGGTCACTAGTTCTGGGTCAGAGACCAGT GCGTTTTCAAATCTAACTGTTGCCTCAAGTCAACCAGAGACCATAGACTCATGGGTCGCT CATCCTGGGACAGAAGCAAGTTCTGTTGTTCCAACTTTGACTGTCTCCACTGGTGAGCCG TTTACAAATATCTCATTGGTCACCCATCCTGCAGAGAGTAGCTCAACTCTTCCCAGGACA ACCTCAAGGTTTTCCCACAGTGAATTAGACACTATGCCTTCTACAGTCACCAGTCCTGAG GCAGAATCCAGCTCAGCCATTTCAACAACTATTTCACCTGGTATACCAGGTGTGCTGACA TCACTGGTCACTAGCTCTGGGAGAGACATCAGTGCAACTTTTCCAACAGTGCCTGAGTCC CCACATGAATCAGAGGCAACAGCCTCATGGGTTACTCATCCTGCAGTCACCAGCACAACA GTTCCCAGGACAACCCCTAATTATTCTCATAGTGAACCAGACACCACACCATCAATAGCC ACCAGTCCTGGGGCAGAAGCCACTTCAGATTTTCCAACAATAACTGTCTCACCTGATGTA CCAGATATGGTAACCTCACAGGTCACTAGTTCTGGGACAGACACCAGTATAACTATTCCA ACTCTGACTCTTTCTTCTGGTGAGCCAGAGACCACAACCTCATTTATCACCTATTCTGAG ACACACACAAGTTCAGCCATTCCAACTCTCCCTGTCTCCCCTGGTGCATCAAAGATGCTG ACCTCACTGGTCATCAGTTCTGGGACAGACAGCACTACAACTTTCCCAACACTGACGGAG ACCCCATATGAACCAGAGACAACAGCCATACAGCTCATTCATCCTGCAGAGACCAACACA ATGGTTCCCAGGACAACTCCCAAGTTTTCCCATAGTAAGTCAGACACCACACTCCCAGTA GCCATCACCAGTCCTGGGCCAGAAGCCAGTTCAGCTGTTTCAACGACAACTATCTCACCT GATATGTCAGATCTGGTGACCTCACTGGTCCCTAGTTCTGGGACAGACACCAGTACAACC TTCCCAACATTGAGTGAGACCCCATATGAACCAGAGACTACAGCCACGTGGCTCACTCAT CCTGCAGAAACCAGCACAACGGTTTCTGGGACAATTCCCAACTTTTCCCATAGGGGATCA GACACTGCACCCTCAATGGTCACCAGTCCTGGAGTAGACACGAGGTCAGGTGTTCCAACT ACAACCATCCCACCCAGTATACCAGGGGTAGTGACCTCACAGGTCACTAGTTCTGCAACA GACACTAGTACAGCTATTCCAACTTTGACTCCTTCTCCTGGTGAACCAGAGACCACAGCC TCATCAGCTACCCATCCTGGGACACAGACTGGCTTCACTGTTCCAATTCGGACTGTTCCC TCTAGTGAGCCAGATACAATGGCTTCCTGGGTCACTCATCCTCCACAGACCAGCACACCT GTTTCCAGAACAACCTCCAGTTTTTCCCATAGTAGTCCAGATGCCACACCTGTAATGGCC ACCAGTCCTAGGACAGAAGCCAGTTCAGCTGTACTGACAACAATCTCACCTGGTGCACCA GAGATGGTGACTTCACAGATCACTAGTTCTGGGGCAGCAACCAGTACAACTGTTCCAACT TTGACTCATTCTCCTGGTATGCCAGAGACCACAGCCTTATTGAGCACCCATCCCAGAACA GAGACAAGTAAAACATTTCCTGCTTCAACTGTGTTTCCTCAAGTATCAGAGACCACAGCC TCACTCACCATTAGACCTGGTGCAGAGACTAGCACAGCTCTCCCAACTCAGACAACATCC TCTCTCTTCACCCTACTTGTAACTGGAACCAGCAGAGTTGATCTAAGTCCAACTGCTTCA CCTGGTGTTTCTGCAAAAACAGCCCCACTTTCCACCCATCCAGGGACAGAAACCAGCACA ATGATTCCAACTTCAACTCTTTCCCTTGGTTTACTAGAGACTACAGGCTTACTGGCCACC AGCTCTTCAGCAGAGACCAGCACGAGTACTCTAACTCTGACTGTTTCCCCTGCTGTCTCT GGGCTTTCCAGTGCCTCTATAACAACTGATAAGCCCCAAACTGTGACCTCCTGGAACACA GAAACCTCACCATCTGTAACTTCAGTTGGACCCCCAGAATTTTCCAGGACTGTCACAGGC ACCACTATGACCTTGATACCATCAGAGATGCCAACACCACCTAAAACCAGTCATGGAGAA GGAGTGAGTCCAACCACTATCTTGAGAACTACAATGGTTGAAGCCACTAATTTAGCTACC ACAGGTTCCAGTCCCACTGTGGCCAAGACAACAACCACCTTCAATACACTGGCTGGAAGC CTCTTTACTCCTCTGACCACACCTGGGATGTCCACCTTGGCCTCTGAGAGTGTGACCTCA AGAACAAGTTATAACCATCGGTCCTGGATCTCCACCACCAGCAGTTATAACCGTCGGTAC TGGACCCCTGCCACCAGCACTCCAGTGACTTCTACATTCTCCCCAGGGATTTCCACATCC TCCATCCCCAGCTCCACAGCAGCCACAGTCCCATTCATGGTGCCATTCACCCTCAACTTC ACCATCACCAACCTGCAGTACGAGGAGGACATGCGGCACCCTGGTTCCAGGAAGTTCAAC GCCACAGAGAGAGAACTGCAGGGTCTGCTCAAACCCTTGTTCAGGAATAGCAGTCTGGAA TACCTCTATTCAGGCTGCAGACTAGCCTCACTCAGGCCAGAGAAGGATAGCTCAGCCACG GCAGTGGATGCCATCTGCACACATCGCCCTGACCCTGAAGACCTCGGACTGGACAGAGAG CGACTGTACTGGGAGCTGAGCAATCTGACAAATGGCATCCAGGAGCTGGGCCCCTACACC CTGGACCGGAACAGTCTCTATGTCAATGGTTTCACCCATCGAAGCTCTATGCCCACCACC AGCACTCCTGGGACCTCCACAGTGGATGTGGGAACCTCAGGGACTCCATCCTCCAGCCCC AGCCCCACGACTGCTGGCCCTCTCCTGATGCCGTTCACCCTCAACTTCACCATCACCAAC CTGCAGTACGAGGAGGACATGCGTCGCACTGGCTCCAGGAAGTTCAACACCATGGAGAGT GTCCTGCAGGGTCTGCTCAAGCCCTTGTTCAAGAACACCAGTGTTGGCCCTCTGTACTCT GGCTGCAGATTGACCTTGCTCAGGCCCGAGAAAGATGGGGCAGCCACTGGAGTGGATGCC ATCTGCACCCACCGCCTTGACCCCAAAAGCCCTGGACTCAACAGGGAGCAGCTGTACTGG GAGCTAAGCAAACTGACCAATGACATTGAAGAGCTGGGCCCCTACACCCTGGACAGGAAC AGTCTCTATGTCAATGGTTTCACCCATCAGAGCTCTGTGTCCACCACCAGCACTCCTGGG ACCTCCACAGTGGATCTCAGAACCTCAGGGACTCCATCCTCCCTCTCCAGCCCCACAATT ATGGCTGCTGGCCCTCTCCTGGTACCATTCACCCTCAACTTCACCATCACCAACCTGCAG TATGGGGAGGACATGGGTCACCCTGGCTCCAGGAAGTTCAACACCACAGAGAGGGTCCTG CAGGGTCTGCTTGGTCCCATATTCAAGAACACCAGTGTTGGCCCTCTGTACTCTGGCTGC AGACTGACCTCTCTCAGGTCTGAGAAGGATGGAGCAGCCACTGGAGTGGATGCCATCTGC ATCCATCATCTTGACCCCAAAAGCCCTGGACTCAACAGAGAGCGGCTGTACTGGGAGCTG AGCCAACTGACCAATGGCATCAAAGAGCTGGGCCCCTACACCCTGGACAGGAACAGTCTC TATGTCAATGGTTTCACCCATCGGACCTCTGTGCCCACCAGCAGCACTCCTGGGACCTCC ACAGTGGACCTTGGAACCTCAGGGACTCCATTCTCCCTCCCAAGCCCCGCAACTGCTGGC CCTCTCCTGGTGCTGTTCACCCTCAACTTCACCATCACCAACCTGAAGTATGAGGAGGAC ATGCATCGCCCTGGCTCCAGGAAGTTCAACACCACTGAGAGGGTCCTGCAGACTCTGCTT GGTCCTATGTTCAAGAACACCAGTGTTGGCCTTCTGTACTCTGGCTGCAGACTGACCTTG CTCAGGTCCGAGAAGGATGGAGCAGCCACTGGAGTGGATGCCATCTGCACCCACCGTCTT GACCCCAAAAGCCCTGGAGTGGACAGGGAGCAGCTATACTGGGAGCTGAGCCAGCTGACC AATGGCATCAAAGAGCTGGGCCCCTACACCCTGGACAGGAACAGTCTCTATGTCAATGGT TTCACCCATTGGATCCCTGTGCCCACCAGCAGCACTCCTGGGACCTCCACAGTGGACCTT GGGTCAGGGACTCCATCCTCCCTCCCCAGCCCCACAACTGCTGGCCCTCTCCTGGTGCCG TTCACCCTCAACTTCACCATCACCAACCTGAAGTACGAGGAGGACATGCATTGCCCTGGC TCCAGGAAGTTCAACACCACAGAGAGAGTCCTGCAGAGTCTGCTTGGTCCCATGTTCAAG AACACCAGTGTTGGCCCTCTGTACTCTGGCTGCAGACTGACCTTGCTCAGGTCCGAGAAG GATGGAGCAGCCACTGGAGTGGATGCCATCTGCACCCACCGTCTTGACCCCAAAAGCCCT GGAGTGGACAGGGAGCAGCTATACTGGGAGCTGAGCCAGCTGACCAATGGCATCAAAGAG CTGGGTCCCTACACCCTGGACAGAAACAGTCTCTATGTCAATGGTTTCACCCATCAGACC TCTGCGCCCAACACCAGCACTCCTGGGACCTCCACAGTGGACCTTGGGACCTCAGGGACT CCATCCTCCCTCCCCAGCCCTACATCTGCTGGCCCTCTCCTGGTGCCATTCACCCTCAAC TTCACCATCACCAACCTGCAGTACGAGGAGGACATGCATCACCCAGGCTCCAGGAAGTTC AACACCACGGAGCGGGTCCTGCAGGGTCTGCTTGGTCCCATGTTCAAGAACACCAGTGTC GGCCTTCTGTACTCTGGCTGCAGACTGACCTTGCTCAGGCCTGAGAAGAATGGGGCAGCC ACTGGAATGGATGCCATCTGCAGCCACCGTCTTGACCCCAAAAGCCCTGGACTCAACAGA GAGCAGCTGTACTGGGAGCTGAGCCAGCTGACCCATGGCATCAAAGAGCTGGGCCCCTAC ACCCTGGACAGGAACAGTCTCTATGTCAATGGTTTCACCCATCGGAGCTCTGTGGCCCCC ACCAGCACTCCTGGGACCTCCACAGTGGACCTTGGGACCTCAGGGACTCCATCCTCCCTC CCCAGCCCCACAACAGCTGTTCCTCTCCTGGTGCCGTTCACCCTCAACTTTACCATCACC AATCTGCAGTATGGGGAGGACATGCGTCACCCTGGCTCCAGGAAGTTCAACACCACAGAG AGGGTCCTGCAGGGTCTGCTTGGTCCCTTGTTCAAGAACTCCAGTGTCGGCCCTCTGTAC TCTGGCTGCAGACTGATCTCTCTCAGGTCTGAGAAGGATGGGGCAGCCACTGGAGTGGAT GCCATCTGCACCCACCACCTTAACCCTCAAAGCCCTGGACTGGACAGGGAGCAGCTGTAC TGGCAGCTGAGCCAGATGACCAATGGCATCAAAGAGCTGGGCCCCTACACCCTGGACCGG AACAGTCTCTACGTCAATGGTTTCACCCATCGGAGCTCTGGGCTCACCACCAGCACTCCT TGGACTTCCACAGTTGACCTTGGAACCTCAGGGACTCCATCCCCCGTCCCCAGCCCCACA ACCACCGGCCCTCTCCTGGTGCCATTCACACTCAACTTCACCATCACTAACCTACAGTAT GAGGAGAACATGGGTCACCCTGGCTCCAGGAAGTTCAACATCACGGAGAGTGTTCTGCAG GGTCTGCTCAAGCCCTTGTTCAAGAGCACCAGTGTTGGCCCTCTGTATTCTGGCTGCAGA CTGACCTTGCTCAGGCCTGAGAAGGATGGAGTAGCCACCAGAGTGGACGCCATCTGCACC CACCGCCCTGACCCCAAAATCCCTGGGCTAGACAGACAGCAGCTATACTGGGAGCTGAGC CAGCTGACCCACAGCATCACTGAGCTGGGACCCTACACCCTGGATAGGGACAGTCTCTAT GTCAATGGTTTCACCCAGCGGAGCTCTGTGCCCACCACCAGCACTCCTGGGACTTTCACA GTACAGCCGGAAACCTCTGAGACTCCATCATCCCTCCCTGGCCCCACAGCCACTGGCCCT GTCCTGCTGCCATTCACCCTCAATTTTACCATCACTAACCTGCAGTATGAGGAGGACATG CGTCGCCCTGGCTCCAGGAAGTTCAACACCACGGAGAGGGTCCTTCAGGGTCTGCTTATG CCCTTGTTCAAGAACACCAGTGTCAGCTCTCTGTACTCTGGTTGCAGACTGACCTTGCTC AGGCCTGAGAAGGATGGGGCAGCCACCAGAGTGGATGCTGTCTGCACCCATCGTCCTGAC CCCAAAAGCCCTGGACTGGACAGAGAGCGGCTGTACTGGAAGCTGAGCCAGCTGACCCAC GGCATCACTGAGCTGGGCCCCTACACCCTGGACAGGCACAGTCTCTATGTCAATGGTTTC ACCCATCAGAGCTCTATGACGACCACCAGAACTCCTGATACCTCCACAATGCACCTGGCA ACCTCGAGAACTCCAGCCTCCCTGTCTGGACCCATGACCGCCAGCCCTCTCCTGGTGCTA TTCACAATTAACTTCACCATCACTAACCTGCGGTATGAGGAGAACATGCATCACCCTGGC TCTAGAAAGTTTAACACCACGGAGAGAGTCCTTCAGGGTCTGCTCAGGCCTGTGTTCAAG AACACCAGTGTTGGCCCTCTGTACTCTGGCTGCAGACTGACCTTGCTCAGGCCCAAGAAG GATGGGGCAGCCACCAAAGTGGATGCCATCTGCACCTACCGCCCTGATCCCAAAAGCCCT GGACTGGACAGAGAGCAGCTATACTGGGAGCTGAGCCAGCTGACCCACAGCATCACTGAG CTGGGCCCCTACACCCTGGACAGGGACAGTCTCTATGTCAATGGTTTCACACAGCGGAGC TCTGTGCCCACCACTAGCATTCCTGGGACCCCCACAGTGGACCTGGGAACATCTGGGACT CCAGTTTCTAAACCTGGTCCCTCGGCTGCCAGCCCTCTCCTGGTGCTATTCACTCTCAAC TTCACCATCACCAACCTGCGGTATGAGGAGAACATGCAGCACCCTGGCTCCAGGAAGTTC AACACCACGGAGAGGGTCCTTCAGGGCCTGCTCAGGTCCCTGTTCAAGAGCACCAGTGTT GGCCCTCTGTACTCTGGCTGCAGACTGACTTTGCTCAGGCCTGAAAAGGATGGGACAGCC ACTGGAGTGGATGCCATCTGCACCCACCACCCTGACCCCAAAAGCCCTAGGCTGGACAGA GAGCAGCTGTATTGGGAGCTGAGCCAGCTGACCCACAATATCACTGAGCTGGGCCCCTAT GCCCTGGACAACGACAGCCTCTTTGTCAATGGTTTCACTCATCGGAGCTCTGTGTCCACC ACCAGCACTCCTGGGACCCCCACAGTGTATCTGGGAGCATCTAAGACTCCAGCCTCGATA TTTGGCCCTTCAGCTGCCAGCCATCTCCTGATACTATTCACCCTCAACTTCACCATCACT AACCTGCGGTATGAGGAGAACATGTGGCCTGGCTCCAGGAAGTTCAACACTACAGAGAGG GTCCTTCAGGGCCTGCTAAGGCCCTTGTTCAAGAACACCAGTGTTGGCCCTCTGTACTCT GGCTGCAGGCTGACCTTGCTCAGGCCAGAGAAAGATGGGGAAGCCACCGGAGTGGATGCC ATCTGCACCCACCGCCCTGACCCCACAGGCCCTGGGCTGGACAGAGAGCAGCTGTATTTG GAGCTGAGCCAGCTGACCCACAGCATCACTGAGCTGGGCCCCTACACACTGGACAGGGAC AGTCTCTATGTCAATGGTTTCACCCATCGGAGCTCTGTACCCACCACCAGCACCGGGGTG GTCAGCGAGGAGCCATTCACACTGAACTTCACCATCAACAACCTGCGCTACATGGCGGAC ATGGGCCAACCCGGCTCCCTCAAGTTCAACATCACAGACAACGTCATGCAGCACCTGCTC AGTCCTTTGTTCCAGAGGAGCAGCCTGGGTGCACGGTACACAGGCTGCAGGGTCATCGCA CTAAGGTCTGTGAAGAACGGTGCTGAGACACGGGTGGACCTCCTCTGCACCTACCTGCAG CCCCTCAGCGGCCCAGGTCTGCCTATCAAGCAGGTGTTCCATGAGCTGAGCCAGCAGACC CATGGCATCACCCGGCTGGGCCCCTACTCTCTGGACAAAGACAGCCTCTACCTTAACGGT TACAATGAACCTGGTCCAGATGAGCCTCCTACAACTCCCAAGCCAGCCACCACATTCCTG CCTCCTCTGTCAGAAGCCACAACAGCCATGGGGTACCACCTGAAGACCCTCACACTCAAC TTCACCATCTCCAATCTCCAGTATTCACCAGATATGGGCAAGGGCTCAGCTACATTCAAC TCCACCGAGGGGGTCCTTCAGCACCTGCTCAGACCCTTGTTCCAGAAGAGCAGCATGGGC CCCTTCTACTTGGGTTGCCAACTGATCTCCCTCAGGCCTGAGAAGGATGGGGCAGCCACT GGTGTGGACACCACCTGCACCTACCACCCTGACCCTGTGGGCCCCGGGCTGGACATACAG CAGCTTTACTGGGAGCTGAGTCAGCTGACCCATGGTGTCACCCAACTGGGCTTCTATGTC CTGGACAGGGATAGCCTCTTCATCAATGGCTATGCACCCCAGAATTTATCAATCCGGGGC GAGTACCAGATAAATTTCCACATTGTCAACTGGAACCTCAGTAATCCAGACCCCACATCC TCAGAGTACATCACCCTGCTGAGGGACATCCAGGACAAGGTCACCACACTCTACAAAGGC AGTCAACTACATGACACATTCCGCTTCTGCCTGGTCACCAACTTGACGATGGACTCCGTG TTGGTCACTGTCAAGGCATTGTTCTCCTCCAATTTGGACCCCAGCCTGGTGGAGCAAGTC TTTCTAGATAAGACCCTGAATGCCTCATTCCATTGGCTGGGCTCCACCTACCAGTTGGTG GACATCCATGTGACAGAAATGGAGTCATCAGTTTATCAACCAACAAGCAGCTCCAGCACC CAGCACTTCTACCTGAATTTCACCATCACCAACCTACCATATTCCCAGGACAAAGCCCAG CCAGGCACCACCAATTACCAGAGGAACAAAAGGAATATTGAGGATGCGCTCAACCAACTC TTCCGAAACAGCAGCATCAAGAGTTATTTTTCTGACTGTCAAGTTTCAACATTCAGGTCT GTCCCCAACAGGCACCACACCGGGGTGGACTCCCTGTGTAACTTCTCGCCACTGGCTCGG AGAGTAGACAGAGTTGCCATCTATGAGGAATTTCTGCGGATGACCCGGAATGGTACCCAG CTGCAGAACTTCACCCTGGACAGGAGCAGTGTCCTTGTGGATGGGTATTCTCCCAACAGA AATGAGCCCTTAACTGGGAATTCTGACCTTCCCTTCTGGGCTGTCATCCTCATCGGCTTG GCAGGACTCCTGGGAGTCATCACATGCCTGATCTGCGGTGTCCTGGTGACCACCCGCCGG CGGAAGAAGGAAGGAGAATACAACGTCCAGCAACAGTGCCCAGGCTACTACCAGTCACAC CTAGACCTGGAGGATCTGCAATGA
- Chromosome Location
- 19
- Locus
- 19p13.2
- External Identifiers
Resource Link UniProtKB ID Q8WXI7 UniProtKB Entry Name MUC16_HUMAN GenBank Gene ID AF414442 GenAtlas ID MUC16 HGNC ID HGNC:15582 - General References
- Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, Hellsten U, Goodstein D, Couronne O, Tran-Gyamfi M, Aerts A, Altherr M, Ashworth L, Bajorek E, Black S, Branscomb E, Caenepeel S, Carrano A, Caoile C, Chan YM, Christensen M, Cleland CA, Copeland A, Dalin E, Dehal P, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Garcia C, Georgescu AM, Glavina T, Gomez M, Gonzales E, Groza M, Hammon N, Hawkins T, Haydu L, Ho I, Huang W, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Larionov V, Leem SH, Lopez F, Lou Y, Lowry S, Malfatti S, Martinez D, McCready P, Medina C, Morgan J, Nelson K, Nolan M, Ovcharenko I, Pitluck S, Pollard M, Popkie AP, Predki P, Quan G, Ramirez L, Rash S, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, She X, Smith D, Slezak T, Solovyev V, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wagner M, Wheeler J, Wu K, Xie G, Yang J, Dubchak I, Furey TS, DeJong P, Dickson M, Gordon D, Eichler EE, Pennacchio LA, Richardson P, Stubbs L, Rokhsar DS, Myers RM, Rubin EM, Lucas SM: The DNA sequence and biology of human chromosome 19. Nature. 2004 Apr 1;428(6982):529-35. [Article]
- O'Brien TJ, Beard JB, Underwood LJ, Shigemasa K: The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure. Tumour Biol. 2002 May-Jun;23(3):154-69. [Article]
- O'Brien TJ, Beard JB, Underwood LJ, Dennis RA, Santin AD, York L: The CA 125 gene: an extracellular superstructure dominated by repeat sequences. Tumour Biol. 2001 Nov-Dec;22(6):348-66. [Article]
- Yin BW, Lloyd KO: Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16. J Biol Chem. 2001 Jul 20;276(29):27371-5. Epub 2001 May 21. [Article]
- Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [Article]
- Fendrick JL, Konishi I, Geary SM, Parmley TH, Quirk JG Jr, O'Brien TJ: CA125 phosphorylation is associated with its secretion from the WISH human amnion cell line. Tumour Biol. 1997;18(5):278-89. [Article]
- Kui Wong N, Easton RL, Panico M, Sutton-Smith M, Morrison JC, Lattanzio FA, Morris HR, Clark GF, Dell A, Patankar MS: Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125. J Biol Chem. 2003 Aug 1;278(31):28619-34. Epub 2003 May 6. [Article]
- Rump A, Morikawa Y, Tanaka M, Minami S, Umesaki N, Takeuchi M, Miyajima A: Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion. J Biol Chem. 2004 Mar 5;279(10):9190-8. Epub 2003 Dec 15. [Article]
- McLemore MR, Aouizerat B: Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer. Biol Res Nurs. 2005 Apr;6(4):262-7. [Article]
- Argueso P, Tisdale A, Spurr-Michaud S, Sumiyoshi M, Gipson IK: Mucin characteristics of human corneal-limbal epithelial cells that exclude the rose bengal anionic dye. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):113-9. [Article]