O-GlcNAcase NagJ
Details
- Name
- O-GlcNAcase NagJ
- Synonyms
- 3.2.1.169
- Beta-hexosaminidase
- Beta-N-acetylglucosaminidase
- Beta-N-acetylhexosaminidase
- Hexosaminidase B
- N-acetyl-beta-D-glucosaminidase
- N-acetyl-beta-glucosaminidase
- Gene Name
- nagJ
- Organism
- Clostridium perfringens (strain 13 / Type A)
- Amino acid sequence
>lcl|BSEQ0017074|O-GlcNAcase NagJ MKRKMLKRLLTSAFACMFIANGLITTTVRAVGPKTGEENQVLVPNLNPTPENLEVVGDGF KITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEAL NGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVS ARGIVEGFYGTPWTHKDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPENEMQRMQ ELIDASAENKVDFVFGISPGIDIRFDGEAGEEDFNHLIAKAESLYDMGVRSFAIYWDDIQ DKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRTYTRIFAETVDPS IEVMWTGPGVVTNEIPLSDAQLISGIYNRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLN QYVDFFTVNPMEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFAN HSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLK ANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSS FAVISEKVAQSFIQEALSFDLTLINPRTVKITASSEETSGENAPASFASDGDMNTFWHSK WSSPAHEGPHHLTLELDNVYEINKVKYAPRQDSKNGRITGYKVSVSLDGENFTEVKTGTL EDNAAIKFIEFDSVDAKYVRLDVTDSVSDQANGRGKFATAAEVNVHGKLKEAAEVTGSVS LEALEEVQVGENIEVGVGIDELVNAEAFAYDFTLNYDENAFEYVEAISDDGVFVNAKKIE DGKVRVLVSSLTGEPLPAKEVLAKVVLRAEAKTEGSNLSVTNSSVGDGEGLVHEIAGTEK TVNIIEGTSPEIVVNPVRDFKASEINKKNVTVTWTEPETTEGLEGYILYKDGKKVAEIGK DETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRTAR
- Number of residues
- 1001
- Molecular Weight
- 111107.99
- Theoretical pI
- 4.36
- GO Classification
- Functionsbeta-N-acetylhexosaminidase activity / carbohydrate binding
- General Function
- Carbohydrate binding
- Specific Function
- Binds carbohydrates. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. Can bind and deglycosylate O-glycosylated peptides from mammals. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro).
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0017075|O-GlcNAcase NagJ (nagJ) ATGAAAAGAAAAATGCTTAAAAGACTTTTAACTTCAGCGTTTGCTTGTATGTTTATTGCA AATGGCTTAATAACTACTACTGTAAGAGCTGTAGGACCTAAAACTGGGGAAGAAAACCAG GTTTTAGTTCCAAATTTAAATCCAACACCAGAAAATTTAGAGGTTGTAGGAGATGGATTT AAGATAACTTCTTCTATAAATTTAGTTGGTGAGGAAGAGGCAGATGAGAATGCAGTAAAT GCTTTAAGGGAATTTTTAACTGCAAACAACATAGAAATAAATAGTGAAAATGATCCAAAT TCAACTACCCTTATAATAGGTGAGGTTGATGATGATATTCCTGAGTTAGATGAAGCTTTA AATGGAACTACAGCAGAAAATTTAAAAGAAGAGGGATATGCTTTAGTTTCAAATGATGGG AAAATAGCTATTGAAGGTAAAGATGGAGATGGAACTTTCTATGGAGTTCAAACATTTAAG CAATTAGTTAAGGAATCTAATATACCAGAAGTGAATATAACTGATTATCCAACAGTTAGT GCTAGGGGTATTGTAGAAGGTTTTTATGGAACTCCTTGGACACATAAAGATAGATTAGAT CAGATTAAATTTTATGGAGAAAATAAATTAAACACATATATTTATGCTCCTAAAGATGAT CCATATCACAGAGAAAAATGGAGAGAGCCATATCCAGAAAATGAAATGCAAAGAATGCAA GAACTTATAGATGCTTCTGCTGAAAATAAGGTTGATTTTGTTTTCGGTATTTCTCCAGGA ATAGATATAAGATTTGATGGAGAAGCAGGAGAAGAAGATTTTAATCATTTAATAGCTAAA GCAGAATCTTTATATGACATGGGTGTAAGAAGTTTTGCAATCTATTGGGATGATATTCAA GATAAGAGTGCAGCTAAACATGCTCAAGTTTTAAATAGATTTAATGAAGAATTTGTAAAG GCTAAGGGAGATGTAAAACCATTAATAACAGTCCCAACAGAGTATGATACTGGAGCTATG GTAAGTAATGGACAACCTAGAACTTATACTAGAATTTTTGCAGAAACTGTTGATCCTAGT ATAGAAGTTATGTGGACTGGTCCTGGAGTTGTTACAAATGAAATTCCTTTAAGTGATGCA CAACTTATAAGTGGAATATACAATAGAAATATGGCAGTATGGTGGAATTATCCAGTAACA GATTATTTTAAAGGTAAGCTTGCCTTAGGACCAATGCATGGATTAGATAAAGGATTAAAT CAATATGTAGATTTCTTTACTGTAAATCCAATGGAGCATGCTGAGCTTTCAAAAATATCA ATACACACAGCTGCTGACTATAGCTGGAATATGGATAACTATGATTATGATAAGGCTTGG AATAGAGCAATTGATATGCTTTATGGTGATTTAGCAGAAGATATGAAGGTATTTGCAAAC CATTCAACAAGAATGGACAATAAAACTTGGGCTAAATCAGGAAGAGAAGACGCTCCAGAG CTTAGAGCAAAAATGGATGAGTTATGGAATAAGTTATCTTCTAAAGAAGATGCAAGTGCT CTTATAGAAGAGTTATATGGAGAGTTTGCAAGAATGGAAGAAGCTTGTAATAATCTAAAG GCAAATTTACCTGAAGTTGCTTTAGAAGAATGCTCAAGACAACTTGATGAACTTATTACT TTAGCTCAAGGGGATAAGGCTTCATTAGATATGATTGTAGCTCAATTAAATGAAGATACA GAGGCTTATGAAAGTGCTAAAGAAATTGCACAAAATAAATTAAATACAGCCTTAAGTAGC TTTGCAGTTATATCTGAAAAGGTTGCTCAATCATTTATACAAGAAGCTTTAAGTTTTGAT TTAACATTAATAAATCCAAGAACAGTAAAGATAACAGCTTCATCTGAAGAGACTTCAGGG GAAAATGCACCAGCTTCCTTTGCTTCAGATGGTGATATGAATACTTTCTGGCATAGTAAA TGGTCATCACCTGCTCATGAAGGTCCTCATCATTTAACTTTAGAATTAGATAATGTATAT GAAATAAATAAAGTTAAATATGCTCCAAGACAAGATAGTAAAAATGGAAGAATAACAGGG TATAAAGTATCTGTTAGTTTAGATGGAGAAAACTTTACAGAAGTTAAAACTGGAACTTTA GAAGATAATGCAGCTATTAAATTTATAGAATTTGATAGTGTTGATGCTAAATATGTAAGA TTAGATGTTACAGATAGCGTTTCAGATCAAGCAAATGGTAGAGGAAAATTTGCTACTGCT GCAGAGGTTAATGTTCATGGAAAGTTAAAAGAAGCTGCTGAGGTAACAGGAAGTGTATCT CTTGAAGCTTTAGAGGAAGTTCAAGTTGGAGAAAACATAGAAGTTGGAGTAGGTATAGAC GAATTAGTAAATGCAGAAGCTTTTGCTTATGATTTTACACTAAATTATGATGAAAATGCC TTTGAATATGTAGAAGCAATTTCTGATGATGGAGTGTTTGTAAATGCTAAGAAAATAGAA GACGGAAAGGTTAGAGTGCTTGTAAGTTCTTTAACTGGAGAACCATTGCCAGCTAAAGAA GTTTTAGCTAAGGTTGTCCTAAGAGCAGAAGCTAAAACAGAAGGAAGCAATTTAAGCGTA ACCAATTCATCAGTTGGAGATGGAGAAGGGTTAGTTCATGAGATTGCAGGAACTGAAAAA ACAGTTAATATAATAGAAGGAACTAGTCCAGAAATTGTTGTAAATCCAGTAAGAGATTTT AAAGCATCAGAAATAAATAAAAAGAATGTAACTGTAACTTGGACAGAACCAGAAACAACA GAAGGCTTAGAAGGATATATTCTTTATAAGGATGGTAAAAAGGTAGCTGAAATAGGCAAG GATGAAACTTCTTATACATTTAAAAAGTTAAATAGACATACAATCTATAACTTTAAGATT GCAGCTAAATATTCAAATGGGGAAGTTTCAAGTAAAGAAAGCCTAACTTTAAGAACTGCA AGATAG
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q8XL08 UniProtKB Entry Name OGA_CLOPE GenBank Gene ID BA000016 - General References
- Shimizu T, Ohtani K, Hirakawa H, Ohshima K, Yamashita A, Shiba T, Ogasawara N, Hattori M, Kuhara S, Hayashi H: Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater. Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):996-1001. Epub 2002 Jan 15. [Article]